Gamma delta T cells activation in cancers

Autor: Laplagne, Chloé

Publikováno v: Cancer. Université Paul Sabatier-Toulouse III, 2020. Français. ⟨NNT : 2020TOU30109⟩

Gamma delta T lymphocytes (TL) exhibit structural and functional heterogeneity and form a bridge between innate and adaptive immunity. They include in particular Vgamma9Vdelta2 TL, which represent 1 to 5% of circulating TL, a proportion which can qui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d61a2796c08de4ea67866124d6ed6540
https://theses.hal.science/tel-03124407/document

Vγ9Vδ2 T Cells Activation Through Phosphoantigens Can Be Impaired by a RHOB Rerouting in Lung Cancer

Autor: Laplagne, Chloé, Meddour, Sarah, Figarol, Sarah, Michelas, Marie, Calvayrac, Olivier, Favre, Gilles, Laurent, Camille, Fournié, Jean-Jacques, Cabantous, Stéphanie, Poupot, Mary

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2020, 11, ⟨10.3389/fimmu.2020.01396⟩
Frontiers in Immunology, 2020, 11, ⟨10.3389/fimmu.2020.01396⟩

International audience; Vγ9Vδ2 T cells are known to be efficient anti-tumor effectors activated through phosphoantigens (PAg) that are naturally expressed by tumor cells or induced by amino bisphosphonates treatment. This PAg-activation which is TC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0319cfb2f3b50ae45d613a44d8b93695
https://hal.archives-ouvertes.fr/hal-03025949

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