Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Laphalle Fuller"'
Autor:
Manuel Carreno, Rolando Garcia-Morales, Robert Cirocco, Violet Esquenazi, Anne Rosen, Gary Kleiner, Joshua Miller, Laphalle Fuller, Gaetano Ciancio, Bonnie B. Blomberg, Camillo Ricordi, Jeffrey J. Gaynor, George W. Burke, James M. Mathew
Publikováno v:
Transplantation. 83:1611-1619
Background. We update more favorable 10-year deceased donor kidney transplant survival in 63 recipients infused perioperatively with donor vertebral body bone marrow (DBMC-i) vs. 219 noninfused controls having equivalent immunosuppression and demogra
Autor:
George W. Burke, Anne Rosen, Joshua Miller, Robert Cirocco, Ana Hernandez, Yide Jin, Violet Esquenazi, Laphalle Fuller, Gaetano Ciancio
Publikováno v:
Human Immunology. 68:350-361
Renal transplant rejection and graft versus host reactions between HLA genetically-identical sibling (HLAgi) donor/recipient (D/R) pairs are thought to result from minor histocompatibility antigen (mHAg) disparities. We have compared two methods of m
Autor:
Laphalle Fuller, Gaetano Ciancio, Andreas G. Tzakis, Yide Jin, Joshua Miller, Violet Esquenazi, Bonnie B. Blomberg, Camillo Ricordi, George W. Burke
Publikováno v:
Immunological Investigations. 36:213-232
We have shown in ex vivo studies in donor bone marrow-infused kidney transplant recipients, that chimeric cells of either donor or recipient origin taken from the recipient's bone marrow down-regulated the recipient's cellular immune responses. In th
Autor:
Yide Jin, Joshua Miller, Anne Rosen, Violet Esquenazi, George W. Burke, Camillo Ricordi, Andreas G. Tzakis, Laphalle Fuller, Gaetano Ciancio
Publikováno v:
Human Immunology. 66:637-643
We have previously reported in laboratory volunteers ( in vitro ) and renal transplant recipients ( ex vivo ) that bone marrow cells (BMC) are potent downregulators of the immune response. Also, the use of alemtuzumab (Campath-1H, C1H) for immunodepl
Autor:
Violet Esquenazi, Rolando Garcia-Morales, Robert Cirocco, Manuel Carreno, Yide Jin, James M. Mathew, Bonnie B. Blomberg, Camillo Ricordi, Laphalle Fuller, Gaetano Ciancio, Joshua Miller, George W. Burke, Andreas G. Tzakis
Publikováno v:
Transplant Immunology. 11:307-321
Infusions of donor bone marrow derived cells (DBMC) continue to be tested in clinical protocols intended to induce specific immunologic tolerance of solid organ transplants based on the observations that donor-specific tolerance is induced this way i
Autor:
Laphalle Fuller, Gaetano Ciancio, Camillo Ricordi, Violet Esquenazi, Norma S. Kenyon, Bonnie B. Blomberg, Andreas G. Tzakis, Joshua Miller, George W. Burke, James M. Mathew
Publikováno v:
Journal of Immunological Methods. 272:67-80
Since cell-mediated lympholysis (CML), the most commonly used in vitro experimental cytotoxic method for the evaluation of regulatory cells, requires large numbers of cells that are often the limiting factor, we have developed a new micro-cell-mediat
Autor:
Joshua Miller, Laphalle Fuller, Gaetano Ciancio, Manuel Carreno, James M. Mathew, Andreas G. Tzakis, George W. Burke, Camillo Ricordi, Violet Esquenazi
Publikováno v:
Human Immunology. 64:21-30
We have reported a beneficial effect of donor vertebral body bone marrow cells (DBMC) infusions in cadaver renal allograft recipients in a 6-year follow-up, but with a transient increase in early (6 month) postoperative CMV infections and concomitant
Autor:
Yu Tao Wei, Manuel Carreno, Violet Esquenazi, Yide Jin, Bonnie B. Blomberg, Laphalle Fuller, Gaetano Ciancio, Joshua Miller, George W. Burke, Andreas G. Tzakis, Camillo Ricordi
Publikováno v:
Human Immunology. 63:567-575
We have previously demonstrated that bone marrow cells (BMC) inhibit the generation of autologous Epstein-Barr virus (EBV) -specific cytotoxic T lymphocytes (CTL). It was also observed that CD3 + cells obtained after 7 days of culture in the presence
Autor:
Anne Rosen, George W. Burke, Manuel Carreno, David Roth, Camillo Ricordi, Laphalle Fuller, Violet Esquenazi, Gaetano Ciancio, Warren Kupin, Joshua Miller, Andreas G. Tzakis, Rolando Garcia-Morales
Publikováno v:
Transplantation. 71:827-835
Background. To date, several single- and multicenter clinical trials have attempted to induce specific immunological unresponsiveness using donor bone marrow cell infusions to augment solid organ transplantation, but the outcomes have not been defini
Autor:
Rolando Garcia-Morales, Andreas G. Tzakis, Joshua Miller, Manuel Carreno, Laphalle Fuller, George W. Burke, James M. Mathew, Violet Esquenazi, Camillo Ricordi
Publikováno v:
Transplantation. 70:1752-1760
Background The identity of the cells in the human bone marrow that function as effective regulators of in vitro and possibly in vivo cellular immune responses is not well established. Methods. Cell subpopulations were isolated from cadaver donor vert