No benefit from TMZ treatment in glioblastoma with truly unmethylated MGMT promoter: Reanalysis of the CE.6 and the pooled Nordic/NOA-08 trials in elderly glioblastoma patients.

Autor: Hegi ME; Neurosurgery & Neuroscience Research Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Oppong FB; European Organisation for Research and Treatment of Cancer (EORTC) Headquarters, Brussels, Belgium., Perry JR; Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Wick W; DKTK and Clinical Cooperation Unit Neurooncology, DKFZ, Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Henriksson R; Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden., Laperriere NJ; Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Gorlia T; European Organisation for Research and Treatment of Cancer (EORTC) Headquarters, Brussels, Belgium., Malmström A; Department of Advanced Home Care in Linköping, and Division of Cellbiology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden., Weller M; Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland.

Publikováno v: Neuro-oncology [Neuro Oncol] 2024 Oct 03; Vol. 26 (10), pp. 1867-1875.

Corrigendum to: Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG 08.02) randomized clinical trial.

Autor: Song AJ; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Ding K; Department of Public Health Sciences, Canadian Cancer Trials Group, Queen's University, Kingston, Ontario, Canada., Alnahhas I; Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Laperriere NJ; Department of Radiation Oncology, Princess Margaret Cancer Center, Toronto, Ontario, Canada., Perry J; Department of Medicine, Division of Neurology, University of Toronto, Toronto, Ontario, Canada., Mason WP; Department of Medicine, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Winch C; Department of Public Health Sciences, Canadian Cancer Trials Group, Queen's University, Kingston, Ontario, Canada., O'Callaghan CJ; Department of Public Health Sciences, Canadian Cancer Trials Group, Queen's University, Kingston, Ontario, Canada., Menten JJ; Department of Experimental Radiation Oncology, University Hospitals Leuven, Leuven, Belgium., Brandes AA; Department of Medical oncology, IRCCS Istituto Scienze Neurologiche - Bologna, Italy., Phillips C; Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia., Fay MF; Genesis Cancer Care, Newcastle, NSW, Australia., Nishikawa R; Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Hidaka, Japan., Osoba D; QOL Consulting, West Vancouver, British Columbia, Canada., Cairncross JG; Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada., Roa W; Division of Radiation Oncology, Cross Cancer Institute, Edmonton, Alberta, Canada., Wick W; Division of Neurology, Heidelberg University Medical Center, Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Heidelberg, Germany., Shi W; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Publikováno v: Neuro-oncology advances [Neurooncol Adv] 2022 Jan 27; Vol. 4 (1), pp. vdac011. Date of Electronic Publication: 2022 Jan 27 (Print Publication: 2022).

Correlation between Cranial Nerve Microstructural Characteristics and Vestibular Schwannoma Tumor Volume.

Autor: Halawani AM; From the Division of Brain Imaging, and Behaviour-Systems Neuroscience (A.M.H., S.T., P.S.-P.H., D.J.M., M.H.), Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.; Department of Medical Imaging (A.M.H., D.J.M.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neuroradiology (A.M.H., D.J.M.), Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Tohyama S; From the Division of Brain Imaging, and Behaviour-Systems Neuroscience (A.M.H., S.T., P.S.-P.H., D.J.M., M.H.), Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.; Institute of Medical Science, (S.T., P.S.-P.H., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Hung PS; From the Division of Brain Imaging, and Behaviour-Systems Neuroscience (A.M.H., S.T., P.S.-P.H., D.J.M., M.H.), Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.; Institute of Medical Science, (S.T., P.S.-P.H., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Behan B; Ontario Brain Institute (B.B.), Toronto, Ontario, Canada., Bernstein M; Department of Surgery (M.B., S.K., G.Z., M.C., F.G., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery (M.B., S.K., F.G., M.H.), Krembil Neuroscience Centre, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Kalia S; Department of Surgery (M.B., S.K., G.Z., M.C., F.G., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery (M.B., S.K., F.G., M.H.), Krembil Neuroscience Centre, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Zadeh G; Department of Surgery (M.B., S.K., G.Z., M.C., F.G., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; The Arthur and Sonia Labatt Brain Tumor Research Centre (G.Z.), Hospital for Sick Children, Toronto, Ontario, Canada., Cusimano M; Department of Surgery (M.B., S.K., G.Z., M.C., F.G., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery (M.C.), Saint Michael's Hospital, Toronto, Ontario, Canada., Schwartz M; Division of Neurosurgery (M.S.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Gentili F; Department of Surgery (M.B., S.K., G.Z., M.C., F.G., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery (M.B., S.K., F.G., M.H.), Krembil Neuroscience Centre, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Mikulis DJ; From the Division of Brain Imaging, and Behaviour-Systems Neuroscience (A.M.H., S.T., P.S.-P.H., D.J.M., M.H.), Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.; Department of Medical Imaging (A.M.H., D.J.M.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neuroradiology (A.M.H., D.J.M.), Joint Department of Medical Imaging, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Laperriere NJ; Department of Radiation Oncology (N.J.L.), University of Toronto, Toronto, Ontario, Canada.; Division of Radiation Oncology (N.J.L.), Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Hodaie M; From the Division of Brain Imaging, and Behaviour-Systems Neuroscience (A.M.H., S.T., P.S.-P.H., D.J.M., M.H.), Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada mojgan.hodaie@uhn.ca.; Institute of Medical Science, (S.T., P.S.-P.H., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Department of Surgery (M.B., S.K., G.Z., M.C., F.G., M.H.), Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; Division of Neurosurgery (M.B., S.K., F.G., M.H.), Krembil Neuroscience Centre, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.

Publikováno v: AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] 2021 Oct; Vol. 42 (10), pp. 1853-1858.

Meningioma Screening With MRI in Childhood Leukemia Survivors Treated With Cranial Radiation.

Autor: Co JL; Radiation Medicine Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Swain M; Radiation Oncology, Tata Memorial Hospital, Mumbai, India., Murray LJ; Radiotherapy Research Group, St James's University Hospital and University of Leeds, Leeds, UK., Ahmed S; Radiation Medicine Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Laperriere NJ; Radiation Medicine Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Tsang DS; Radiation Medicine Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Yu E; Radiology and Medical Imaging, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Pintilie M; Biostatistics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Weiss J; Biostatistics, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada., Hodgson DC; Radiation Medicine Program, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada; Pediatric Oncology Group of Ontario (POGO), Toronto, Ontario, Canada. Electronic address: david.hodgson@rmp.uhn.ca.

Publikováno v: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2019 Jul 01; Vol. 104 (3), pp. 640-643. Date of Electronic Publication: 2019 Mar 14.

MGMT promoter methylation status testing to guide therapy for glioblastoma: refining the approach based on emerging evidence and current challenges.

Autor: Mansouri A; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada., Hachem LD; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada., Mansouri S; MacFeeters Hamilton Centre for Neuro-Oncology Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Nassiri F; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; MacFeeters Hamilton Centre for Neuro-Oncology Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Laperriere NJ; Department of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Xia D; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada., Lindeman NI; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Wen PY; Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA., Chakravarti A; Radiation Oncology, The Ohio State University College of Medicine, Columbus, Ohio, USA., Mehta MP; Department of Radiation Oncology, Miami Cancer Institute, Miami, Florida, USA., Hegi ME; Department of Clinical Neurosciences, Lausanne University Hospital, Lausanne, Switzerland., Stupp R; Malnati Brain Tumor Institute of the Lurie Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Aldape KD; Department of Laboratory Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA., Zadeh G; Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.; MacFeeters Hamilton Centre for Neuro-Oncology Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.; Division of Neurosurgery, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.

Publikováno v: Neuro-oncology [Neuro Oncol] 2019 Feb 14; Vol. 21 (2), pp. 167-178.