Zobrazeno 1 - 10
of 1 042
pro vyhledávání: '"Lapachol"'
Autor:
Sued Eustaquio Mendes Miranda, Janaina de Alcantara Lemos, Flaviano Melo Ottoni, Geovanni Dantas Cassali, Danyelle M. Townsend, Carolina de Aguiar Ferreira, Ricardo Jose Alves, Lucas Antonio Miranda Ferreira, Andre Luis Branco de Barros
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116054- (2024)
Breast cancer prevails as the most common cancer in women, underscoring an urgent need for more effective therapies. This study explores the potential of our newly developed nanoemulsion containing a novel fucoside derivative of lapachol (NE-F-LapA)
Externí odkaz:
https://doaj.org/article/4fb50a2dc4654d829e31b29e7d94a4bc
Autor:
Abdur Rauf, Taghrid S. AlOmar, Sehrish Sarfaraz, Khurshid Ayub, Fahad Hussain, Umer Rashid, Najla Almasoud, Abdulaziz S. AlOmar, Gauhar Rehman, Zubair Ahmad, Naveed Muhammad, Zafar Ali Shah, Dorota Formanowicz
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22575- (2023)
Medicinal plants are the main source of active chemical constituents responsible for curing or mitigating various ailments. To discover new, safe, and effective drug candidates the isolation and screening of natural products are essential. In the cur
Externí odkaz:
https://doaj.org/article/8a181f4ce276478dbc367fad4e60b472
Akademický článek
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Autor:
Felipe Revoredo Benatti, Keoma Keyson Lima Cavalcante, Alexandre Orsato, Carla Cristina Perez
Publikováno v:
Orbital: The Electronic Journal of Chemistry, Vol 12, Iss 4, Pp 282-290 (2020)
Malaria is a disease that still plagues many tropical countries, affecting around 228 million people and with approximately 430 thousand deaths worldwide. The resistance of the causative protozoan against the existing antimalarials has been increasin
Externí odkaz:
https://doaj.org/article/05ec76b1348d4fa2b7386d640b5690dc
Autor:
Amanda A. Borges, Michele P. de Souza, Anna Carolina C. da Fonseca, Guilherme F. Wermelinger, Ruan C. B. Ribeiro, Adriane A. P. Amaral, Cláudio José C. de Carvalho, Lucas S. Abreu, Lucas Nicolau de Queiroz, Elan C. P. de Almeida, Vitor W. Rabelo, Paula A. Abreu, Bruno Pontes, Vitor F. Ferreira, Fernando de C. da Silva, Luana da S. M. Forezi, Bruno K. Robbs
Publikováno v:
Molecules, Vol 28, Iss 1, p 309 (2022)
Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, accounting for approximately 90% of all oral cancers, and is the eighth most common cancer in men. Cisplatin and carboplatin are the main chemotherapy drugs used in the clinic.
Externí odkaz:
https://doaj.org/article/91cc9dcabd21467cb4e362422dc6a0af
Autor:
Rone A. De Grandis, Katia M. Oliveira, Adriana P. M. Guedes, Patrick W. S. dos Santos, Alexandre F. Aissa, Alzir A. Batista, Fernando R. Pavan
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Lapachol is a well-studied natural product that has been receiving great interest due to its anticancer properties that target oxidative stress. In the present work, two novel lapachol-containing ruthenium(II) complexes [Ru(Lap)(dppm)(bipy)]PF6 (1) a
Externí odkaz:
https://doaj.org/article/7181f5e8a1484fe8bc75eda9a6edd6a1
Autor:
Miguel A. Martínez-Cabrera, Mario A. Macías, Francisco Ferreira, Enrique Pandolfi, Javier Barúa, Leopoldo Suescun
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 75, Iss 9, Pp 1362-1366 (2019)
Lapachol acetate [systematic name: 3-(3-methylbut-2-enyl)-1,4-dioxonaphthalen-2-yl acetate], C17H16O4, was prepared using a modified high-yield procedure and its crystal structure is reported for the first time 80 years after its first synthesis. The
Externí odkaz:
https://doaj.org/article/18f2c51554554982a1d927fa8bd2d80c
Akademický článek
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Autor:
Maycon Renan Santos Lima, Katieli da Silva Souza Campanholi, Elza Aparecida da Silva, Flávia Amanda Pedroso de Morais, Évelin Lemos de Oliveira, Expedito Leite Silva, Wilker Caetano
Publikováno v:
Colloquium Exactarum, Vol 13, Iss 1 (2021)
Este artigo contempla aspectos relacionados a capacidade de interação e monomerização do fármaco lapachol com os sistemas nanoestruturados micelares F127 e P123. Para isso, estudos prévios de agregação foram conduzidos para descrição da din
Externí odkaz:
https://doaj.org/article/c48972cc565649b8a522305721a1a43b