Zobrazeno 1 - 10
of 931
pro vyhledávání: '"Lanzer P"'
Autor:
Candice N. Baker, Debra Duso, Nagarama Kothapalli, Tricia Hart, Sean Casey, Tres Cookenham, Larry Kummer, Janine Hvizdos, Kathleen Lanzer, Purva Vats, Priya Shanbhag, Isaac Bell, Mike Tighe, Kelsey Travis, Frank Szaba, Jeffrey M. Harder, Olivia Bedard, Natalie Oberding, Jerrold M. Ward, Mark D. Adams, Cathleen Lutz, Shelton S. Bradrick, William W. Reiley, Nadia A. Rosenthal
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Mutations in SARS-CoV-2 variants of concern (VOCs) have expanded the viral host range beyond primates, and a few other mammals, to mice, affording the opportunity to exploit genetically diverse mouse panels to model the broad spectrum of res
Externí odkaz:
https://doaj.org/article/2c9c9826453141688a649f8f972e01a2
Autor:
Elizabeth J. Martinez, William C. Chang, Wei-Hung Chen, Agnes Hajduczki, Paul V. Thomas, Jaime L. Jensen, Misook Choe, Rajeshwer S. Sankhala, Caroline E. Peterson, Phyllis A. Rees, Jordan Kimner, Sandrine Soman, Caitlin Kuklis, Letzibeth Mendez-Rivera, Vincent Dussupt, Jocelyn King, Courtney Corbett, Sandra V. Mayer, Aldon Fernandes, Kripa Murzello, Tres Cookenham, Janine Hvizdos, Larry Kummer, Tricia Hart, Kathleen Lanzer, Julian Gambacurta, Matthew Reagan, Debbie Duso, Sandhya Vasan, Natalie D. Collins, Nelson L. Michael, Shelly J. Krebs, Gregory D. Gromowski, Kayvon Modjarrad, John Kaundinya, M. Gordon Joyce
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110624- (2024)
Summary: The rapid emergence of SARS-CoV-2 variants of concern (VoC) and the threat of future zoonotic sarbecovirus spillover emphasizes the need for broadly protective next-generation vaccines and therapeutics. We utilized SARS-CoV-2 spike ferritin
Externí odkaz:
https://doaj.org/article/d044a7b730b34c81a3817a63324aa1dd
Autor:
In-Jeong Kim, Olga Gonzalez, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Kelsey L. Travis, Timothy C. Low-Beer, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Corinna N. Ross, Stephanie D. Mdaki, Kathleen M. Brasky, Donna Layne-Colon, Suzette D. Tardif, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman, Jean L. Patterson
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Zika virus (ZIKV) infection during pregnancy poses significant threats to maternal and fetal health, leading to intrauterine fetal demise and severe developmental malformations that constitute congenital Zika syndrome (CZS). As such, the dev
Externí odkaz:
https://doaj.org/article/b9add105d8704c0d82513d7770efca3f
Autor:
In-Jeong Kim, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Amanda A. Schneck, Jerrold Ward, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Zika virus (ZIKV) is a significant threat to pregnant women and their fetuses as it can cause severe birth defects and congenital neurodevelopmental disorders, referred to as congenital Zika syndrome (CZS). Thus, a safe and effective ZIKV va
Externí odkaz:
https://doaj.org/article/dbc43c97314347e0a2f015da2e56b4ce
Autor:
Martin Borlich, Uwe Zeymer, Harm Wienbergen, Hans-Peter Hobbach, Alessandro Cuneo, Raffi Bekeredjian, Oliver Ritter, Birgit Hailer, Klaus Hertting, Marcus Hennersdorf, Werner Scholtz, Peter Lanzer, Harald Mudra, Markus Schwefer, Peter-Lothar Schwimmbeck, Christoph Liebetrau, Holger Thiele, Christoph Claas, Thomas Riemer, Ralf Zahn, Leon Iden, Gert Richardt, Ralph Toelg
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 1, Pp 89-101 (2023)
Abstract Introduction The preference for using transradial access (TRA) over transfemoral access (TFA) in patients requiring percutaneous coronary intervention (PCI) is based on evidence suggesting that TRA is associated with less bleeding and fewer
Externí odkaz:
https://doaj.org/article/f9664d75a011444aa006c451e76fe60d
Autor:
Micha Rosenkranz, Kristin Fürle, Julia Hibbert, Anne Ulmer, Arin Ali, Thomas Giese, Antje Blank, Walter E. Haefeli, Ernst Böhnlein, Michael Lanzer, Richard Thomson-Luque
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Radical control of malaria likely requires a vaccine that targets both the asymptomatic liver stages and the disease-causing blood stages of the human malaria parasite Plasmodium falciparum. While substantial progress has been made towards l
Externí odkaz:
https://doaj.org/article/8a2370c07fb045ea9013c090061948cc
A network medicine approach to study comorbidities in heart failure with preserved ejection fraction
Autor:
Jan D. Lanzer, Alberto Valdeolivas, Mark Pepin, Hauke Hund, Johannes Backs, Norbert Frey, Hans-Christoph Friederich, Jobst-Hendrik Schultz, Julio Saez-Rodriguez, Rebecca T. Levinson
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background Comorbidities are expected to impact the pathophysiology of heart failure (HF) with preserved ejection fraction (HFpEF). However, comorbidity profiles are usually reduced to a few comorbid disorders. Systems medicine approaches ca
Externí odkaz:
https://doaj.org/article/954624ff61ec4154835d0ef6cd653c9e
Autor:
Fiona Berger, Guillermo M. Gomez, Cecilia P. Sanchez, Britta Posch, Gabrielle Planelles, Farzin Sohraby, Ariane Nunes-Alves, Michael Lanzer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The chloroquine resistance transporter, PfCRT, of the human malaria parasite Plasmodium falciparum is sensitive to acidic pH. Consequently, PfCRT operates at 60% of its maximal drug transport activity at the pH of 5.2 of the digestive vacuol
Externí odkaz:
https://doaj.org/article/4481fd0850c543e2a8b0bb81ca74a0e9
Autor:
Fabian Kalt, Martin Hüllner, Moritz C. Wurnig, Gregoire B. Morand, Martina A. Broglie, Paul Stolzmann, Martin Lanzer
Publikováno v:
Advances in Oral and Maxillofacial Surgery, Vol 13, Iss , Pp 100464- (2024)
Background: Human papilloma virus (HPV) infection is an important risk factor in oropharyngeal cancer. Several studies have analyzed the association of tumoral HPV status and different imaging parameters in FDG-PET/CT and magnetic resonance (MR) diff
Externí odkaz:
https://doaj.org/article/9c47a1984e1d49f9a1e0733784fb5d1a
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