Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Lanxia Meng"'
Autor:
Xingyu Zhang, Li Tang, Jiaolong Yang, Lanxia Meng, Jiehui Chen, Lingyan Zhou, Jiangyu Wang, Min Xiong, Zhentao Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane protein that is predominantly expressed by microglia in the brain. The proteolytic shedding of TREM2 results in the release of soluble TREM2 (sTREM2), which is incre
Externí odkaz:
https://doaj.org/article/90e9fd820b654888b94f4b2a49a105f3
Autor:
Xingyu Zhang, Li Zou, Li Tang, Min Xiong, Xiao-Xin Yan, Lanxia Meng, Guiqin Chen, Jing Xiong, Shuke Nie, Zhaohui Zhang, Qiang Chen, Zhentao Zhang
Publikováno v:
PLoS Biology, Vol 22, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/e0ff0fbafbd9416aa99275a70842e6fc
Autor:
Lanxia Meng, Congcong Liu, Miao Liu, Jiehui Chen, Chaoyang Liu, Zhaohui Zhang, Guiqin Chen, Zhentao Zhang
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113342- (2023)
Summary: The molecular mechanisms that trigger Tau aggregation in Alzheimer’s disease (AD) remain elusive. Fungi, especially Saccharomyces cerevisiae (S. cerevisiae), can be found in brain samples from patients with AD. Here, we show that the yeast
Externí odkaz:
https://doaj.org/article/2264be41c1ec4abf855ba5e5e79ac784
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundTau phosphorylation is a pathological hallmark of Alzheimer’s disease (AD). Previously, we reported that the γ-adducin 1–357 fragment is present in the brains of AD patients. However, it remains unknown how γ-adducin regulates tau pho
Externí odkaz:
https://doaj.org/article/d3f8254559dc4cc69f0c8c8a3772f75e
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-18 (2022)
Abstract Background The pathologic accumulation and aggregation of tau is a hallmark of tauopathies including Alzheimer’s disease (AD). However, the molecular mechanisms mediating tau aggregation in AD remain elusive. The incidence of AD is increas
Externí odkaz:
https://doaj.org/article/b0ea55631f1845e98156fa31325dd5fb
Autor:
Chaoyang Liu, Zehua Liu, Yanyan Fang, Zizhuo Liao, Zhibing Zhang, Xin Yuan, Ting Yu, Yunying Yang, Min Xiong, Xingyu Zhang, Guoxin Zhang, Lanxia Meng, Zhentao Zhang
Publikováno v:
Environment International, Vol 171, Iss , Pp 107696- (2023)
Maneb, a widely-used dithiocarbamate fungicide, remains in the environment and exerts adverse health effects. Epidemiological evidence shows that maneb exposure is associated with a higher risk of Parkinson’s disease (PD), one of the most common ne
Externí odkaz:
https://doaj.org/article/893b5d5af8e14ad6bb2ef95d7929f483
Autor:
Ye Tian, Lina Pan, Xin Yuan, Min Xiong, Zhaohui Zhang, Lanxia Meng, Yongfa Zheng, Lihong Bu, Ximing Xu, Zhentao Zhang
Publikováno v:
Neurobiology of Disease, Vol 169, Iss , Pp 105736- (2022)
Parkinson's disease (PD) is the most common motor-associated neurodegenerative disease. Although the pathogenesis of PD is still wrapped in the mist, accumulating evidence indicates that mitochondrial dysfunction contributes to the onset and progress
Externí odkaz:
https://doaj.org/article/0e68e82b8ff64f5a944de12a76760015
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is a receptor mainly expressed on the surface of microglia. It mediates multiple pathophysiological processes in various diseases. Recently, TREM2 has been found to play a role in the
Externí odkaz:
https://doaj.org/article/c82aedcc2dee4ffca339915c00f63f1a
Autor:
Zhixiang Tan, Zhiguo Yu, Xiaobo Xu, Lanxia Meng, Mosheng Yu, Rui Tao, Yingliang Wu, Zhanyong Zhu
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Scorpion peptides have good therapeutic effect on chronic ulcer of diabetic foot, but the related pharmacological mechanism has remained unclear. The different proteins and bacteria present in ulcer exudates from chronic diabetic foot patients, treat
Externí odkaz:
https://doaj.org/article/a2f1afcd991e49b88d46e067796f433c
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Silica nanoparticles (SiO2 NPs) are increasingly investigated for their potential in drug delivery systems. However, the neurotoxicity of SiO2 NPs remains to be fully clarified. Previously SiO2 NPs have been reported to be detected in the central ner
Externí odkaz:
https://doaj.org/article/6a2b750dda5448d6a024de91b6dd726f