Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Lanxi Song"'
Autor:
Takeshi Yoshida, Lanxi Song, Yun Bai, Fumi Kinose, Jiannong Li, Kim C Ohaegbulam, Teresita Muñoz-Antonia, Xiaotao Qu, Steven Eschrich, Hidetaka Uramoto, Fumihiro Tanaka, Patrick Nasarre, Robert M Gemmill, Joëlle Roche, Harry A Drabkin, Eric B Haura
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147344 (2016)
Epithelial-mesenchymal transition (EMT) is one mechanism of acquired resistance to inhibitors of the epidermal growth factor receptor-tyrosine kinases (EGFR-TKIs) in non-small cell lung cancer (NSCLC). The precise mechanisms of EMT-related acquired r
Externí odkaz:
https://doaj.org/article/3c458785300d4584b84ebdf4b59582e9
Autor:
Jiannong Li, Keiryn Bennett, Alexey Stukalov, Bin Fang, Guolin Zhang, Takeshi Yoshida, Isamu Okamoto, Jae‐Young Kim, Lanxi Song, Yun Bai, Xiaoning Qian, Bhupendra Rawal, Michael Schell, Florian Grebien, Georg Winter, Uwe Rix, Steven Eschrich, Jacques Colinge, John Koomen, Giulio Superti‐Furga, Eric B Haura
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
We hypothesized that elucidating the interactome of epidermal growth factor receptor (EGFR) forms that are mutated in lung cancer, via global analysis of protein–protein interactions, phosphorylation, and systematically perturbing the ensuing netwo
Externí odkaz:
https://doaj.org/article/bc792efbcc2c4d1ebd85fd51a06f5c26
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
Table S1. Mutational status of all specimens regarding KRAS and EGFR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0558ee243093eb10b379e99d8337928b
https://doi.org/10.1158/1535-7163.22501750
https://doi.org/10.1158/1535-7163.22501750
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
Legends for Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad27c05d4ad01847a6b6a1f6db2d6b8c
https://doi.org/10.1158/1535-7163.22501753.v1
https://doi.org/10.1158/1535-7163.22501753.v1
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
Figure S1. Cross-docking of sunitinib and dasatinib in NQO2 and PDXK.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83313c2b1d59069df2bbc1af23aae775
https://doi.org/10.1158/1535-7163.22501759
https://doi.org/10.1158/1535-7163.22501759
Autor:
Uwe Rix, Keiryn L. Bennett, Giulio Superti-Furga, Jarrod A. Marto, Eric B. Haura, Jacques Colinge, Katja Parapatics, Lanxi Song, Florian P. Breitwieser, Scott B. Ficarro, Manuela Gridling
A growing number of gene mutations, which are recognized as cancer drivers, can be successfully targeted with drugs. The redundant and dynamic nature of oncogenic signaling networks and complex interactions between cancer cells and the microenvironme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69de964373b89e60639ecede13aca671
https://doi.org/10.1158/1535-7163.c.6536884.v1
https://doi.org/10.1158/1535-7163.c.6536884.v1
Autor:
Eric B. Haura, Uwe Rix, Yian Ann Chen, Kate Fisher, Jamie K. Teer, John M. Koomen, Lanxi Song, Fumi Kinose, Bin Fang, January M. Watters, Jae-Young Kim, Yun Bai
Supplementary Methods. Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeda1cc841be685536403f9b5f149a0
https://doi.org/10.1158/0008-5472.22405002.v1
https://doi.org/10.1158/0008-5472.22405002.v1
Autor:
Eric B. Haura, Uwe Rix, Yian Ann Chen, Kate Fisher, Jamie K. Teer, John M. Koomen, Lanxi Song, Fumi Kinose, Bin Fang, January M. Watters, Jae-Young Kim, Yun Bai
Supplementary Table S5. Bliss analysis summary of drug combinations with dasatinib in DDR2-mutant squamous cell carcinoma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fbfde43b37d38a1aa66175f22a68e9
https://doi.org/10.1158/0008-5472.22404987.v1
https://doi.org/10.1158/0008-5472.22404987.v1
Mutations of the epidermal growth factor receptor (EGFR) selectively activate Akt and signal transducer and activator of transcription (STAT) pathways that are important in lung cancer cell survival. Src family kinases can cooperate with receptor tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048531c23a568b6d95d15bfe129bb72b
https://doi.org/10.1158/0008-5472.c.6494058.v1
https://doi.org/10.1158/0008-5472.c.6494058.v1
Autor:
Eric B. Haura, Uwe Rix, Yian Ann Chen, Kate Fisher, Jamie K. Teer, John M. Koomen, Lanxi Song, Fumi Kinose, Bin Fang, January M. Watters, Jae-Young Kim, Yun Bai
Supplementary Figures S1-S5. Quantification of Western blotting bands (S1); LC-MRM analysis of IGF-1R and EGFR tyrosine phosphorylation (S2); Validation of drug effect (S3); Dasatinib-based drug combinations in DDR2-mutant squamous cell lung carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631a228f0c8cf0b70fe47224a03a23a2
https://doi.org/10.1158/0008-5472.22405005.v1
https://doi.org/10.1158/0008-5472.22405005.v1