Single-cell transcriptomics of alloreactive CD4+ T cells over time reveals divergent fates during gut graft-versus-host disease.

Autor: Engel JA; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Lee HJ; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Williams CG; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Kuns R; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Olver S; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Lansink LI; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Soon MS; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia., Andersen SB; Institute for Molecular Bioscience, University of Queensland, St. Lucia, Queensland, Australia., Powell JE; Garvan-Weizmann Centre for Cellular Genomics, Sydney, New South Wales, Australia.; UNSW Cellular Genomics Futures Institute, University of New South Wales, Sydney, New South Wales, Australia., Svensson V; Flagship Labs 60 Inc., Cambridge, Massachusetts, USA., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom., Hill GR; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Division of Medical Oncology, University of Washington, Seattle, Washington, USA., Varelias A; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.; Faculty of Medicine, University of Queensland, St. Lucia, Queensland, Australia., Koyama M; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Haque A; QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.; Department of Microbiology and Immunology, University of Melbourne, located at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

Publikováno v: JCI insight [JCI Insight] 2020 Jul 09; Vol. 5 (13). Date of Electronic Publication: 2020 Jul 09.