The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis

Autor: Kobayashi, Hiroki, Gieniec, Krystyna A., Lannagan, Tamsin R.M., Wang, Tongtong, Asai, Naoya, Mizutani, Yasuyuki, Iida, Tadashi, Ando, Ryota, Thomas, Elaine M., Sakai, Akihiro, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A., Vrbanac, Laura, Ng, Jia Q., Goyne, Jarrad, Radford, Georgette, Lawrence, Matthew J., Sammour, Tarik, Hayakawa, Yoku, Klebe, Sonja, Shin, Alice E., Asfaha, Samuel, Bettington, Mark L., Rieder, Florian, Arpaia, Nicholas, Danino, Tal, Butler, Lisa M., Burt, Alastair D., Leedham, Simon J., Rustgi, Anil K., Mukherjee, Siddhartha, Takahashi, Masahide, Wang, Timothy C., Enomoto, Atsushi, Woods, Susan L., Worthley, Daniel L.

Publikováno v: In Gastroenterology March 2022 162(3):890-906

Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer

Autor: Corry, Shania M., McCorry, Amy M.B., Lannagan, Tamsin R.M., Leonard, Niamh A., Fisher, Natalie C., Byrne, Ryan M., Tsantoulis, Petros, Cortes-Lavaud, Xabier, Amirkhah, Raheleh, Redmond, Keara L., McCooey, Aoife J., Malla, Sudhir B., Rogan, Emily, Sakhnevych, Svetlana, Gillespie, Michael A., White, Mark, Richman, Susan D., Jackstadt, Rene-Filip, Campbell, Andrew D., Maguire, Sarah, McDade, Simon S., Longley, Daniel B., Loughrey, Maurice B., Coleman, Helen G., Kerr, Emma M., Tejpar, Sabine, Maughan, Timothy, Leedham, Simon J., Small, Donna M., Ryan, Aideen E., Sansom, Owen J., Lawler, Mark, Dunne, Philip D.

Publikováno v: Corry, S M, McCorry, A MB, Lannagan, T R M, Leonard, N A, Fisher, N C, Byrne, R M, Tsantoulis, P, Cortes-Lavaud, X, Amirkhah, R, Redmond, K L, McCooey, A J, Malla, S B, Rogan, E, Sakhnevych, S, Gillespie, M, White, M, Richman, S, Jackstadt, R, Campbell, C A, Maguire, S, McDade, S S, Longley, D B, Loughrey, M B, Coleman, H G, Kerr, E M, Tejpar, S, Maughan, T, Leedham, S, Small, D M, Ryan, A, Sansom, O J, Lawler, M & Dunne, P D 2022, ' Activation of innate-adaptive immune machinery by Poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer ', Gut, vol. 71, no. 12, pp. 2502–2517 . https://doi.org/10.1136/gutjnl-2021-326183

ObjectiveStroma-rich tumours represent a poor prognostic subtype in stage II/III colon cancer (CC), with high relapse rates and limited response to standard adjuvant chemotherapy.DesignTo address the lack of efficacious therapeutic options for patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875eeb666f186d25f2b8bf1f45cb4d85
https://eprints.gla.ac.uk/270354/1/270354.pdf

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia

Autor: Gil Vazquez, Ester, Nasreddin, Nadia, Valbuena, Gabriel N., Mulholland, Eoghan J., Belnoue-Davis, Hayley L., Eggington, Holly R., Schenck, Ryan O., Wouters, Valérie M., Wirapati, Pratyaksha, Gilroy, Kathryn, Lannagan, Tamsin R.M., Flanagan, Dustin J., Najumudeen, Arafath K., Omwenga, Sulochana, McCorry, Amy M.B., Easton, Alistair, Koelzer, Viktor H., East, James E., Morton, Dion, Trusolino, Livio, Maughan, Timothy, Campbell, Andrew D., Loughrey, Maurice B., Dunne, Philip D., Tsantoulis, Petros, Huels, David J., Tejpar, Sabine, Sansom, Owen J., Leedham, Simon J.

Publikováno v: Cell Stem Cell; November 2022, Vol. 29 Issue: 11 p1612-1612, 1p

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Autor: Li, Jun¹, Woods, Susan L.², Healey, Sue¹, Beesley, Jonathan¹, Chen, Xiaoqing¹, Lee, Jason S.¹, Sivakumaran, Haran¹, Wayte, Nicci¹, Nones, Katia¹, Waterfall, Joshua J.³, Pearson, John^1,4, Patch, Anne-Marie¹, Senz, Janine⁵, Ferreira, Manuel A.¹, Kaurah, Pardeep⁶, Mackenzie, Robertson⁷, Heravi-Moussavi, Alireza⁸, Hansford, Samantha⁵, Lannagan, Tamsin R.M.², Spurdle, Amanda B.¹

Publikováno v: American Journal of Human Genetics. May2016, Vol. 98 Issue 5, p830-842. 13p.