Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lanling Zou"'
As antibiotic resistance increases and the rate of antibiotic development slows, it is becoming more urgent to develop novel approaches to prevent and mitigate serious bacterial and fungal infections. Healthcare-associated infections (HAIs), includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4f8834a3db6ad2150c3737ef57fcb9
https://europepmc.org/articles/PMC5006206/
https://europepmc.org/articles/PMC5006206/
Autor:
Louis H. Miller, Harry M. Meade, Anthony W. Stowers, Lanling Zou, Lynn Lambert, Michael C. Kennedy, Allan Saul, Li-How Chen, David C. Kaslow, Carole A. Long, Yanling Zhang, Timothy J. Rice
Publikováno v:
Proceedings of the National Academy of Sciences. 99:339-344
Two strains of transgenic mice have been generated that secrete into their milk a malaria vaccine candidate, the 42-kDa C-terminal portion of Plasmodium falciparum merozoite surface protein 1 (MSP1 42 ). One strain secretes an MSP1 42 with an amino a
Autor:
James R. Goss, Scot D. Styren, Lanling Zou, Steven T. DeKosky, Mark E. O'Malley, Patrick M. Kochanek
Publikováno v:
Experimental Neurology. 149:301-309
Previous studies from our group have demonstrated an upregulation in nerve growth factor (NGF) RNA and protein in the cortex 24 h following traumatic brain injury (TBI) in a rat model. This increase in NGF is suppressed if rats are subjected to 4 h o
Publikováno v:
Endocrinology. 138:1771-1774
The biological actions of growth hormone (GH) are mediated through the growth hormone receptor (GHR). The GHR gene is expressed in a tissue specific manner and multiple variants (V1 to V8) of GHR mRNA have been detected in human tissues. To understan
Autor:
Ram K. Menon, Lanling Zou
Publikováno v:
Endocrinology. 136:5236-5239
Deletional analysis by transient transfection of COS-7 cells with the murine growth hormone (GH) receptor gene promoter for the L1 transcript identified a 16-bp enhancer element located approximately 3.0 kb upstream of the major transcription start s
Publikováno v:
Journal of Biological Chemistry. 270:8851-8859
The growth hormone (GH) receptor is essential for the actions of GH on postnatal growth and metabolism. To identify DNA sequences involved in the regulation of transcription of the murine GH receptor gene, a 17-kilobase genomic clone containing the 5
Publikováno v:
Journal of Biological Chemistry. 269:13346-13352
In a previous study, we have shown that in vivo expression of the cerebellar Purkinje cell-specific gene Pcp-2 is regulated by thyroid hormone (T3) during neonatal development. In addition, transient cotransfection studies using thyroid hormone recep
Publikováno v:
Metabolism: clinical and experimental. 46(1)
Adipose tissue is a growth hormone (GH)-responsive tissue in which GH regulates energy metabolism. GH exerts its effect by interacting with its specific GH receptor (GHR). In rodents, alternative splicing of the nascent transcript from the GHR gene p
Phase 1 Study of Two Merozoite Surface Protein 1 (MSP142) Vaccines for Plasmodium falciparum Malaria
Autor:
Eveline L. Tierney, Elissa Malkin, Andrew C. Orcutt, Anthony W. Stowers, Michael P. Fay, Louis H. Miller, Siddhartha Mahanty, Laura B. Martin, Olga Muratova, Aaron P. Miles, Nicholas J. MacDonald, Carole A. Long, Sanjay Singh, Samuel E. Moretz, David L. Narum, Hong Zhou, Philip T. Leese, Lanling Zou, Ababacar Diouf, Allan Saul
Publikováno v:
PLoS Clinical Trials
Objectives: To assess the safety and immunogenicity of two vaccines, MSP142-FVO/Alhydrogel and MSP142-3D7/Alhydrogel, targeting blood-stage Plasmodium falciparum parasites. Design: A Phase 1 open-label, dose-escalating study. Setting: Quintiles Phase
Publikováno v:
Pediatric Research. 39:93-93
The GHR is essential for the actions of growth hormone on postnatal growth and metabolism. The control of the murine GHR gene expression is complex; at least two 5′-untranslated exons have been identified. These exons, named L1 and L2, are differen