Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Lanlan Zhou"'
Autor:
Hang Lyu, Haotong Tang, Yunlong Feng, Shuyan Hu, Yuyu Wang, Lanlan Zhou, Shanzi Huang, Jiarun Li, Huamei Zhu, Xi He, Weiming Tang, Yi Zhou, Lei Zhang
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundMen who have sex with men (MSM) face significant risks of Chlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) infection. Nevertheless, only limited studies have looked into the site-specific infection and clearance of CT/NG. In ord
Externí odkaz:
https://doaj.org/article/82a284668d514ef38229c4fa9fb4b93e
Autor:
Tej Tummala, Ashley Sanchez Sevilla Uruchurtu, Arielle De La Cruz, Kelsey E. Huntington, Andrew George, Nicholas R. Liguori, Leiqing Zhang, Lanlan Zhou, Abbas E. Abbas, Christopher G. Azzoli, Wafik S. El-Deiry
Publikováno v:
Current Oncology, Vol 30, Iss 11, Pp 9611-9626 (2023)
Pancreatic cancer is a devastating disease with a poor prognosis. Novel chemotherapeutics in pancreatic cancer have shown limited success, illustrating the urgent need for new treatments. Lurbinectedin (PM01183; LY-01017) received FDA approval in 202
Externí odkaz:
https://doaj.org/article/baef67e61ff84cad80cfd50ebbb42934
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0292571 (2024)
User-generated content (UGC) is developing rapidly as an emerging platform form, however, the problem of indirect copyright infringement by algorithms is becoming more and more prominent, and infringement governance has become a key act in the develo
Externí odkaz:
https://doaj.org/article/a5bf780627f148c2983554b88a8e9c77
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115101- (2023)
Itching and pain are distinct unpleasant sensations. The transient receptor potential cation channel subfamily V member 4 (TRPV4) pathway is regarded as a shared pathway that mediates pain and itching. Vitexin (Mujingsu, MJS), a C-glycosylflavonoid,
Externí odkaz:
https://doaj.org/article/f4b09693b6534dcaa7692d77871e81ff
Autor:
Andrew Hsu, Kelsey E. Huntington, Andre De Souza, Lanlan Zhou, Adam J. Olszewski, Nirav P. Makwana, Diana O. Treaba, Ludimila Cavalcante, Francis J. Giles, Howard Safran, Wafik S. El-Deiry, Benedito A. Carneiro
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 417-423 (2022)
GSK-3β is a serine/threonine kinase implicated in tumorigenesis and chemotherapy resistance. GSK-3β blockade downregulates the NF-κB pathway, modulates immune cell PD-1 and tumor cell PD-L1 expression, and increases CD8 + T cell and NK cell functi
Externí odkaz:
https://doaj.org/article/92cb5ee1490243b8bd245afdd67c0799
Autor:
Lanlan Zhou, Zebing Guan, Chaolun Chen, Qiuhua Zhu, Shiqiu Qiu, Yanan Liu, Mingjie Li, Wenbin Zeng, Hong Wang, Yanmin Gao, Yuemei Yuan, Hanling Zhang, Guanqiao Ruan, Xueyi Pan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
IntroductionEnterocytozoon bieneusi (E. bieneusi) Microsporidia can cause opportunistic infections in immunocompromised patients and is also an emerging disease in these individuals. Its clinical manifestations are chronic diarrhea and severe wasting
Externí odkaz:
https://doaj.org/article/39f6d87e955843cfb57d9ec978608b47
Autor:
Lisi Deng, Chunna Li, Ping Chen, Xiaoqing Luo, Xinchun Zheng, Lanlan Zhou, Yi Zhou, Jinyu Xia, Zhongsi Hong
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Concerns regarding potential toxicity and drug-drug interactions during long-term treatment with three-drug active antiretroviral therapy (ART) regimens have been attracting increasing attention. We aimed to evaluate the efficacy
Externí odkaz:
https://doaj.org/article/ba9a46bbaebe448daadc2a64102300aa
Autor:
Kelsey E. Huntington, Anna D. Louie, Praveen R. Srinivasan, Christoph Schorl, Shaolei Lu, David Silverberg, Daniel Newhouse, Zhijin Wu, Lanlan Zhou, Brittany A. Borden, Francis J. Giles, Mark Dooner, Benedito A. Carneiro, Wafik S. El-Deiry
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10870 (2023)
Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that has been implicated in numerous oncogenic processes. GSK-3 inhibitor elraglusib (9-ING-41) has shown promising preclinical and clinical antitumor activity across multiple tumor type
Externí odkaz:
https://doaj.org/article/5b4bc7b6e2544d4e950318211b22c22c
Autor:
Qi Wang, Nan Che, Chengyin Lu, Xiaoxuan Sun, Yanyan Wang, Qiang Wang, Wenfeng Tan, Lanlan Zhou, Xiaojun Zhang, Dong Xu, Lei Gu, Miaojia Zhang
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Introduction Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease which has focal lymphocytic infiltration including a majority of CD4+ T cells. This study was to investigate the correlation of peripheral granzyme B (
Externí odkaz:
https://doaj.org/article/898b152f5b3c450a8e126fd0dfb8f70d
Autor:
Shuai Zhao, Lanlan Zhou, David T. Dicker, Avital Lev, Shengliang Zhang, Eric Ross, Wafik S. El-Deiry
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract A prevalent characteristic of solid tumors is intra-tumoral hypoxia. Hypoxia-inducible factor 1α (HIF1α) predominantly mediates the adaptive response to O2 oscillation and is linked to multiple malignant hallmarks. Here we describe a strat
Externí odkaz:
https://doaj.org/article/30ce6652e7b0462592db9d8531d60dcb