Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Lankupalle D. Jayanthi"'
Autor:
Durairaj Ragu Varman, Padmanabhan Mannangatti, Mark A. Subler, Jolene J. Windle, Sammanda Ramamoorthy, Lankupalle D. Jayanthi
Publikováno v:
Journal of Molecular Neuroscience. 72:1965-1976
Publikováno v:
Pharmacology
Background: Amphetamine (AMPH) and other psychostimulants act on the norepinephrine (NE) transporter (NET) and the dopamine (DA) transporter (DAT) and enhance NE and DA signaling. Both NET and DAT share anatomical and functional characteristics and a
Publikováno v:
J Neurochem
Serotonin (5-HT) transporter (SERT) plays a crucial role in serotonergic transmission in the central nervous system, and any aberration causes serious mental illnesses. Nevertheless, the cellular mechanisms that regulate SERT function and trafficking
Publikováno v:
Handbook of experimental pharmacology. 271
Dynorphin (DYN) is an endogenous neurosecretory peptide which exerts its activity by binding to the family of G protein-coupled receptors, namely the kappa opioid receptor (KOR). Opioids are associated with pain, analgesia, and drug abuse, which play
Autor:
Lankupalle D. Jayanthi, Durairaj Ragu Varman, Jolene J. Windle, Sammanda Ramamoorthy, Mark A. Subler
Publikováno v:
Behav Brain Res
Dopamine (DA) transporter (DAT) is dynamically regulated by several protein kinases and the Thr53 phosphorylation of DAT (pT53-DAT) is documented in heterologous cell models and in rat brain. However, the role of endogenous pT53-DAT in living animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2685f8ba6c2f360caa905650c090ef
https://europepmc.org/articles/PMC8117066/
https://europepmc.org/articles/PMC8117066/
Publikováno v:
The Kappa Opioid Receptor ISBN: 9783030890735
Dynorphin (DYN) is an endogenous neurosecretory peptide which exerts its activity by binding to the family of G protein-coupled receptors, namely the kappa opioid receptor (KOR). Opioids are associated with pain, analgesia, and drug abuse, which play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4c475cadce8bf4a8d812b691c82a85b
https://doi.org/10.1007/164_2021_499
https://doi.org/10.1007/164_2021_499
Autor:
Santhanalakshmi Sundaramurthy, Lankupalle D. Jayanthi, Balasubramaniam Annamalai, Sammanda Ramamoorthy, Devadoss J. Samuvel, Toni S. Shippenberg
Publikováno v:
Neuropharmacology. 113:281-292
Kappa opioid receptor (KOR) agonists produce dysphoria and psychotomimesis. While KOR agonists produce pro-depressant-like effects, KOR antagonists produce anti-depressant-like effects in rodent models. The cellular mechanisms and downstream effector
Publikováno v:
Neuropharmacology. 128
Amphetamine (AMPH)-mediated norepinephrine transporter (NET) downregulation requires NET-T258/S259 trafficking motif. The present study utilizes cell permeable NET-T258/S259 motif interfering peptide, which blocks AMPH-induced NET downregulation, to
Publikováno v:
Journal of Biological Chemistry. 288:28599-28610
Background: Neurokinin-1 receptor (NK1R) activation down-regulates norepinephrine transporter (NET). Results: NET, NK1R, and protein kinase Cα exist in a physical complex and membrane microdomain-specific NET/NK1R/PKCα interaction is coupled to NK1
Autor:
Padmanabhan Mannangatti, Lankupalle D. Jayanthi, Santhanalakshmi Sundaramurthy, Sammanda Ramamoorthy
Publikováno v:
Psychopharmacology. 234(4)
Neurokinin-1 receptor (NK1R) signaling modulates behaviors associated with psychostimulants and opioids. Psychostimulants, such as amphetamine (AMPH) and cocaine, bind to monoamine transporters and alter their functions. Both dopamine and norepinephr