Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lankai Guo"'
Autor:
ElenaAbbie DaleMaguire, Lankai Guo, Michael Byrne, Megan Cannon, Kris Taborn, Priyanka Shiva Prakasha, Kenneth Longo, Naoki Iwamoto, Pachamuthu Kandasamy, Mamoru Shimizu, Pochi Shum, Ashwini Ranade, Raghuvaran Iyer, Keith Bowman, Hailin Yang, Yuan Benny Yin, Fangjun Liu, Susovan Mohapatra, Lilia Macovei, Saurabh Patil, Janice Lansita, Xiao Shelley Hu, Karen Smith, Jaya Goyal, Padma Narayanan, Ken Rhodes, Michael Panzara, Chandra Vargeese
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Michael, Byrne, Vinod, Vathipadiekal, Luciano, Apponi, Naoki, Iwamoto, Pachamuthu, Kandasamy, Kenneth, Longo, Fangjun, Liu, Richard, Looby, Lauren, Norwood, Anee, Shah, Juili Dilip, Shelke, Chikdu, Shivalila, Hailin, Yang, Yuan, Yin, Lankai, Guo, Keith, Bowman, Chandra, Vargeese
Publikováno v:
Translational Vision Science & Technology
Purpose Antisense oligonucleotides have been under investigation as potential therapeutics for many diseases, including inherited retinal diseases. Chemical modifications, such as chiral phosphorothioate (PS) backbone modification, are often used to
Autor:
Yichun Guan1,2, Lankai Guo2, Zukerberg, Lawrence3, Rueda, Bo R.2,4 brueda@mgh.harvard.edu, Styer, Aaron K.2,4 astyer@mgh.harvard.edu
Publikováno v:
Reproductive Biology & Endocrinology. 8/17/2016, Vol. 14, p1-10. 10p.
Autor:
Juili Dilip Shelke, Michael Byrne, Hailin Yang, Pachamuthu Kandasamy, Keith Bowman, Lauren Norwood, Luciano H. Apponi, Kenneth Longo, Yuan Yin, Lankai Guo, Anee Shah, Chandra Vargeese, Vinod Vathipadiekal, Naoki Iwamoto, Chikdu Shakti Shivalila, Fangjun Liu, Richard Looby
Publikováno v:
Translational Vision Science & Technology. 10:23
Purpose Antisense oligonucleotides have been under investigation as potential therapeutics for many diseases, including inherited retinal diseases. Chemical modifications, such as chiral phosphorothioate (PS) backbone modification, are often used to
Autor:
Eli Rothenberg, Lankai Guo, Stephanie V. Blank, Lily Wu, Savvas C. Pavlides, Kuang-Tzu Huang, Bo R. Rueda, Leslie I. Gold, Dylan A. Reid, Khushbakhat Mittal, Timothy Cardozo
Publikováno v:
Endocrinology. 154:4030-4045
In many human cancers, the tumor suppressor, p27kip1 (p27), a cyclin-dependent kinase inhibitor critical to cell cycle arrest, undergoes perpetual ubiquitin-mediated proteasomal degradation by the E3 ligase complex SCF-Skp2/Cks1 and/or cytoplasmic mi
Autor:
David Engler, Michael J. Birrer, Petra A. Sergent, Gayatry Mohapatra, Lei He, Sandra Orsulic, Vinod Vathipadiekal, Lankai Guo, Bo R. Rueda, Whitfield B. Growdon
Publikováno v:
Oncogene. 33:4226-4235
Ovarian cancers are thought to result from the accumulation of multiple genetic aberrations that transform ovarian and/or fallopian tube surface epithelial cells, allowing for their abnormal growth, proliferation and metastasis. In the report present
Autor:
Deepika Nehra, Scott J. Rodig, Bo R. Rueda, Amy Pan, Jonathan L. Tilly, Mark Puder, Lankai Guo, Yvonne A.R. White, Sarah J. Carlson, Hau D. Le, Dori C. Woods, Erica M. Fallon
Publikováno v:
Aging Cell. 11:1046-1054
Women approaching advanced maternal age have extremely poor outcomes with both natural and assisted fertility. Moreover, the incidence of chromosomal abnormalities and birth defects increases with age. As of yet, there is no effective and practical s
Publikováno v:
Reproductive Biology and Endocrinology : RB&E
Background Human uterine leiomyoma (fibroids; LYO) are the most common benign neoplasms in reproductive-aged women. Dysregulated extracellular matrix and irregular LYO reversion-inducing cysteine-rich protein with Kazal motifs (RECK) expression are t
Autor:
Mark Puder, Bo R. Rueda, Lankai Guo, Paul Mitchell, Deepika Nehra, Arthur Nedder, Hau D. Le, Erica M. Fallon
Publikováno v:
Fertility and Sterility. 98:496-502
Objective To determine the effect of sunitinib (Sutent; SU11248; Pfizer), a US Food and Drug Administration-approved receptor tyrosine kinase inhibitor previously shown to reduce de novo pelvic adhesion formation, on reproductive function after surgi
Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress
Publikováno v:
EMBO Reports
Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress Cables1 interacts with TAp63 to protect it from ubiquitin-mediated degradation after exposure to genotoxic stress. Oocytes lacking Cables1 accumulate