Výsledky vyhledávání - "Lanhua, Tang"

Akademický článek

Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study

Autor: Yiwen Long, Lanhua Tang, Yangying Zhou, Shushan Zhao, Hong Zhu

Publikováno v: BMC Medicine, Vol 21, Iss 1, Pp 1-14 (2023)

Abstract Background Evidence from observational studies and clinical trials suggests that the gut microbiota is associated with cancer. However, the causal association between gut microbiota and cancer remains to be determined. Methods We first ident

Externí odkaz: https://doaj.org/article/b65770e5532547fca04179bbd0fb2386

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Akademický článek

Tumor buster - where will the CAR-T cell therapy ‘missile’ go?

Autor: Chunrun Qu, Hao Zhang, Hui Cao, Lanhua Tang, Haoyang Mo, Fangkun Liu, Liyang Zhang, Zhenjie Yi, Lifu Long, Luzhe Yan, Zeyu Wang, Nan Zhang, Peng Luo, Jian Zhang, Zaoqu Liu, Weijie Ye, Zhixiong Liu, Quan Cheng

Publikováno v: Molecular Cancer, Vol 21, Iss 1, Pp 1-53 (2022)

Abstract Chimeric antigen receptor (CAR) T cell (CAR-T cell) therapy based on gene editing technology represents a significant breakthrough in personalized immunotherapy for human cancer. This strategy uses genetic modification to enable T cells to t

Externí odkaz: https://doaj.org/article/4780ca53858f4650a1d0e913fa4dbb5b

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Akademický článek

Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts

Autor: Yuchen Wang, Hao Zhang, Chao Liu, Zeyu Wang, Wantao Wu, Nan Zhang, Longbo Zhang, Jason Hu, Peng Luo, Jian Zhang, Zaoqu Liu, Yun Peng, Zhixiong Liu, Lanhua Tang, Quan Cheng

Publikováno v: Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-53 (2022)

Abstract The discovery of immune checkpoint inhibitors (ICIs) has now been universally acknowledged as a significant breakthrough in tumor therapy after the targeted treatment of checkpoint molecules: anti-programmed cell death protein 1/programmed c

Externí odkaz: https://doaj.org/article/e021c2f81b4048af8e62739308714416

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Akademický článek

Association between long non-coding RNA (lncRNA) GAS5 polymorphism rs145204276 and cancer risk

Autor: Shushan Zhao, Ping Liu, Zhe Ruan, Jianhuang Li, Shan Zeng, Meizuo Zhong, Lanhua Tang

Publikováno v: Journal of International Medical Research, Vol 49 (2021)

Objective The long non-coding RNA (lncRNA) growth arrest‑specific transcript 5 (GAS5) plays an important role in various tumors, and an increasing number of studies have explored the association of the GAS5 rs145204276 polymorphism with cancer risk

Externí odkaz: https://doaj.org/article/2e3ca9a76d604eeaa3d1b33dd419af72

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Akademický článek

Cost-Effectiveness Analysis of First-Line FOLFIRI Combined With Cetuximab or Bevacizumab in Patients With RAS Wild-Type Left-Sided Metastatic Colorectal Cancer

Autor: Jiaqi Han MD, Desheng Xiao PhD, Chongqing Tan PhD, Xiaohui Zeng MD, Huabin Hu MD, Shan Zeng PhD, MD, Qin Jiang MD, Longjiang She MD, Linli Yao MD, Li Li MD, Lanhua Tang PhD, Jian Ma PhD, MD, Jin Huang PhD, MD, Liangfang Shen PhD, MD

Publikováno v: Cancer Control, Vol 27 (2020)

Background: The FIRE-3 phase III clinical trial demonstrated the marked advantage of prolonging the median overall survival of patients with final RAS wild-type (WT) left-sided metastatic colorectal cancer (mCRC) by 38.3 months after treatment with i

Externí odkaz: https://doaj.org/article/86f087976bbc451ea2f0a58444abe768

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Akademický článek

miR-302b inhibits tumorigenesis by targeting EphA2 via Wnt/ β-catenin/EMT signaling cascade in gastric cancer

Autor: Jin Huang, Yijing He, Howard L. Mcleod, Yanchun Xie, Desheng Xiao, Huabin Hu, Pan Chen, Liangfang Shen, Shan Zeng, Xianli Yin, Jie Ge, Li Li, Lanhua Tang, Jian Ma, Zihua Chen

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)

Abstract Background EphA2 is a crucial oncogene in gastric cancer (GC) development and metastasis, this study aims to identify microRNAs that target it and serve as key regulators of gastric carcinogenesis. Methods We identified several potential mic

Externí odkaz: https://doaj.org/article/9da76b4f3d594ce991c85165da7d5fc9

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Construction of Molecular Subtypes and Related Prognostic and Immune Response Models Based on M2 Macrophages in Glioblastoma

Autor: Kai Xiao, Shushan Zhao, Jian Yuan, Yimin Pan, Ya Song, Lanhua Tang

Publikováno v: International Journal of General Medicine

Kai Xiao,1 Shushan Zhao,2 Jian Yuan,1 Yimin Pan,1 Ya Song,2 Lanhua Tang3,4 1Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Peopleâs Republic of China; 2Department of Orthopedics, Xiangya Hospital, Central South

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e483832dbb3fc2663ac98651bbcb4f
http://europepmc.org/articles/PMC8801375

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Atezolizumab versus Pembrolizumab for First-line Treatment in Non-small-cell Lung Cancer with High PD-L1 Expression: A Network Meta-analysis and Cost-effectiveness Analysis from Chinese Perspectives

Autor: Shuqiao Cheng, Jianhuang Li, Bin Li, Lanhua Tang, Tao Yin, Shao Liu

Background: Atezolizumab and pembrolizumab have been approved for treating metastatic non-small-cell lung cancer (NSCLC) patients with high programmed cell death - ligand 1(PD-L1) expression in the first-line setting. This study aimed to compare the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65c15bcec8c2fcf81fe954ebfe411612
https://doi.org/10.21203/rs.3.rs-2457024/v1