Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Autor: Ceyzériat, Kelly, Ben Haim, Lucile, Denizot, Audrey, Pommier, Dylan, Matos, Marco, Guillemaud, Océane, Palomares, Marie-Ange, Abjean, Laurene, Petit, Fanny, Gipchtein, Pauline, Gaillard, Marie-Claude, Guillermier, Martine, Bernier, Sueva, Gaudin, Mylène, Auregan, Gwenaëlle, Joséphine, Charlène, Dechamps, Nathalie, Veran, Julien, Langlais, Valentin, Cambon, Karine, Bemelmans, Alexis-Pierre, Baijer, Jan, Bonvento, Gilles, Dhenain, Marc, Deleuze, Jean-François, Oliet, Stéphane, Brouillet, Emmanuel, Hantraye, Philippe, Carrillo-de Sauvage, Maria-Angeles, Olaso, Robert, Panatier, Aude, Escartin, Carole

Publikováno v: Acta Neuropathologica Communications
Acta Neuropathologica Communications, BioMed Central part of Springer Science, 2018, 6 (1), ⟨10.1186/s40478-018-0606-1⟩
Acta Neuropathologica Communications, 2018, 6 (1), pp.1047. ⟨10.1186/s40478-018-0606-1⟩
Acta Neuropathologica Communications, BioMed Central part of Springer Science, 2018, 6 (1), pp.1047. ⟨10.1186/s40478-018-0606-1⟩
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-23 (2018)

Astrocyte reactivity and neuroinflammation are hallmarks of CNS pathological conditions such as Alzheimer’s disease. However, the specific role of reactive astrocytes is still debated. This controversy may stem from the fact that most strategies us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f890fe6c6c79132b3c80f86d55bc067d
https://hal.archives-ouvertes.fr/hal-02346781

Additional file 5: of Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer’s disease

Autor: Ceyzériat, Kelly, Haim, Lucile Ben, Denizot, Audrey, Pommier, Dylan, Matos, Marco, Guillemaud, Océane, Marie-Ange Palomares, Laurene Abjean, Petit, Fanny, Gipchtein, Pauline, Marie-Claude Gaillard, Guillermier, Martine, Sueva Bernier, Gaudin, Mylène, Aurégan, Gwenaëlle, Joséphine, Charlène, Déchamps, Nathalie, Veran, Julien, Langlais, Valentin, Cambon, Karine, Bemelmans, Alexis, Baijer, Jan, Bonvento, Gilles, Dhenain, Marc, Jean-François Deleuze, Oliet, Stéphane, Brouillet, Emmanuel, Hantraye, Philippe, Maria-Angeles Carrillo-De Sauvage, Olaso, Robert, Panatier, Aude, Escartin, Carole

Table S2. WGCNA: Top 20 most connected genes regulated by SOCS3 in APP astrocytes. Three of the top 20 hub genes, highlighted in bold, are pan or A1 reactive astrocyte genes. (DOCX 17 kb)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1083021bbcf7841d438da6ccd1dec584

Control of NMDA receptor activity via D-serine : role of the astrocytic EphB3 and CB1 receptors

Autor: Langlais, Valentin

Publikováno v: Neurosciences [q-bio.NC]. Université de Bordeaux, 2016. Français. ⟨NNT : 2016BORD0211⟩

Astrocytes are key partners of neurons. In the hippocampus, and more particularly at CA3-CA1 synapses, by releasing D-serine, these glial cells regulate the activity of synaptic Nmethyl-D-aspartate (NMDA) receptors and thus synaptic memory, also know

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::50508f9c27ae08e575a50cb4e7e2c503
https://tel.archives-ouvertes.fr/tel-01502888/document

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