Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Granzyme B cleaves tenascin-C to release its C-terminal domain in rheumatoid arthritis.

Autor: Aubert A; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Liu A; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Kao M; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Goeres J; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Richardson KC; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Nierves L; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Michael Cuccione Childhood Cancer Research Program and the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada., Jung K; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and., Nabai L; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Zhao H; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Orend G; The Tumor Microenvironment Laboratory, INSERM U1109, Hôpital Civil, Institut d'Hématologie et d'Immunologie, Fédération de Médecine Translationnelle de Strasbourg, Strasbourg, France., Krawetz R; McCaig Institute for Bone and Joint Health, Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Lange PF; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Michael Cuccione Childhood Cancer Research Program and the BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada., Younger A; Department of Orthopaedics, Foot & Ankle Research, St. Paul's Hospital, Vancouver, British Columbia, Canada., Chan J; Department of Medicine, Division of Rheumatology, University of British Columbia, Vancouver, British Columbia, Canada.; Arthritis Research Canada, Vancouver, British Columbia, Canada., Granville DJ; International Collaboration on Repair Discoveries (ICORD) Centre, British Columbia Professional Firefighters' Burn and Wound Healing Group, Vancouver Coastal Health Research Institute, and.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Publikováno v: JCI insight [JCI Insight] 2024 Oct 30; Vol. 9 (23). Date of Electronic Publication: 2024 Oct 30.

The Eμ-Ret mouse is a novel model of hyperdiploid B-cell acute lymphoblastic leukemia.

Autor: Farrokhi A; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Atre T; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Rever J; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Fidanza M; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Duey W; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Salitra S; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Myung J; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Guo M; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Jo S; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Uzozie A; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Baharvand F; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Rolf N; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada., Auer F; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, Munich, Germany., Hauer J; Department of Pediatrics, Children's Cancer Research Center, Kinderklinik München Schwabing, School of Medicine, Technical University of Munich, Munich, Germany., Grupp SA; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA., Eydoux P; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Lange PF; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Seif AE; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA., Maxwell CA; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Reid GSD; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada. gregor.reid@ubc.ca.; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada. gregor.reid@ubc.ca.

Publikováno v: Leukemia [Leukemia] 2024 May; Vol. 38 (5), pp. 969-980. Date of Electronic Publication: 2024 Mar 22.

Shift of the insoluble content of the proteome in the aging mouse brain.

Autor: Molzahn C; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.; Edward Leong Center for Healthy Aging, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Kuechler ER; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Zemlyankina I; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Nierves L; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.; Michael Cuccione Childhood Cancer Research Program, British Columbia Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada., Ali T; Faculty of Veterinary Medicine and Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 4Z6, Canada., Cole G; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.; British Columbia Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada., Wang J; Division of Neurology and Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Albu RF; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Zhu M; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Cashman NR; Division of Neurology and Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Gilch S; Faculty of Veterinary Medicine and Hotchkiss Brain Institute, University of Calgary, Calgary, AB T2N 4Z6, Canada., Karsan A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.; British Columbia Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada., Lange PF; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.; Michael Cuccione Childhood Cancer Research Program, British Columbia Children's Hospital Research Institute, Vancouver, BC V5Z 4H4, Canada.; British Columbia Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada., Gsponer J; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Mayor T; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.; Edward Leong Center for Healthy Aging, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Nov 07; Vol. 120 (45), pp. e2310057120. Date of Electronic Publication: 2023 Oct 31.

Positional proteomics: is the technology ready to study clinical cohorts?

Autor: Lange PF; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.; Michael Cuccione Childhood Cancer Research Program, BC Children's Hospital Research Institute, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada., Schilling O; Institute of Surgical Pathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany., Huesgen PF; Central Institute for Engineering, Electronics and Analytics, ZEA-3, Forschungszentrum Jülich, Jülich, Germany.; Cologne Excellence Cluster on Stress Responses in Ageing-Associated Diseases, CECAD, Medical Faculty and University Hospital, University of Cologne, Cologne, Germany.; Institute of Biochemistry, Department for Chemistry, University of Cologne, Cologne, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.

Publikováno v: Expert review of proteomics [Expert Rev Proteomics] 2023 Jul-Dec; Vol. 20 (12), pp. 309-318. Date of Electronic Publication: 2023 Dec 30.