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Akademický článek

Worldwide distribution of NAT2 diversity: Implications for NAT2 evolutionary history

Autor: Gérard Nathalie, Darlu Pierre, Langaney André, Sabbagh Audrey, Krishnamoorthy Rajagopal, Poloni Estella S

Publikováno v: BMC Genetics, Vol 9, Iss 1, p 21 (2008)

Abstract Background The N-acetyltransferase 2 (NAT2) gene plays a crucial role in the metabolism of many drugs and xenobiotics. As it represents a likely target of population-specific selection pressures, we fully sequenced the NAT2 coding region in

Externí odkaz: https://doaj.org/article/21dd8232f8874ee2aa2461e67b7d7326

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Akademický článek

Génétique formelle des pigmentations humaines à variations continues: beaucoup d'hypothèses, peu de conclusions

Autor: Bonaiti Catherine, Langaney A

Publikováno v: Genetics Selection Evolution, Vol 13, Iss 1, Pp 37-42 (1981)

Externí odkaz: https://doaj.org/article/6545f362c3b9427196a9ffa355df485c

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Akademický článek

Haplotype tagging efficiency and tagSNP sets portability in worldwide populations in NAT2 gene

Autor: Audrey Sabbagh, Pierre Darlu, André Langaney, Estella S. Poloni

Publikováno v: Bulletins et Mémoires de la Société d’Anthropologie de Paris, Vol 19, Iss 4, Pp 233-241 (2007)

Genetic polymorphism in the NAT2 gene is responsible for pronounced interindividual differences in the acetylation activity of the N-acetyltransferase 2 (NAT2) enzyme, which plays a crucial role in the metabolism of many clinically useful drugs and e

Externí odkaz: https://doaj.org/article/ad18af4a7b7e4da8add3f2ed48dbe860

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