Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Lang-Chong He"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 2, Pp 115-120 (2011)
The epidermal growth factor receptors (EGFRs) in some tumor cells are significant targets for drug discovery. In this work, we have developed an EGFR cell membrane chromatography and online high performance liquid chromatography/mass spectrometry sys
Externí odkaz:
https://doaj.org/article/76ad92386c36434ead0b04cd0bb78c17
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 1, Iss 2, Pp 81-91 (2011)
In China, traditional Chinese medicines (TCMs) have been used in clinical applications for thousands of years. The successful hyphenation of high-Performance liquid chromatography (HPLC) and mass spectrometry (MS) has been applied widely in TCMs and
Externí odkaz:
https://doaj.org/article/e19e9994be284c2d84d9ac05ee773143
Autor:
Bo Li, Hong-Yu Jin, Fei-Ya Luo, Shu-xia Xing, Lei Sun, Lang-chong He, Tian-Tian Zuo, Fei Gao, Shuang-Cheng Ma, Huai-Zhen He
Publikováno v:
Environmental Science and Pollution Research. 29:26513-26523
In the present study, the oral bioavailability of cadmium (Cd) in earthworms and leeches was investigated through in vitro physiologically based extraction test (PBET) digestion/Caco2 and MDKC cell models. We are the first to create an innovative ass
Autor:
Shuang-Cheng Ma, Hong-Yu Jin, Yuanjun Shen, Tian-Tian Zuo, Qi Wang, Huai-Zhen He, Lang-chong He, Yao-Lei Li, Lei Zhang, Lei Sun, Fei Gao
Publikováno v:
Environmental Monitoring and Assessment. 191
Little is known about the extent of heavy metal accumulation in traditional Chinese medicines (TCMs). In this study, the levels of lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) in traditional animal medicines were monitored using inductivel
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 107:976-981
Caulophine is a novel fluorenone alkaloid isolated from the radix of Caulophyllum robustum Maxim. Caulophine showed high affinity for the rat myocardial cell membrane as assessed by cell membrane chromatography, suggesting that the compound may exert
Publikováno v:
European Journal of Pharmacology. 647:126-131
Store-operated Ca(2+) entry (SOCE) has recently been proposed to contribute to Ca(2+) influx in vascular smooth muscle cells (VSMCs). Imperatorin is known for its potent vasodilatory effects as a dietary furanocoumarin. The study was designed to exam
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 46:170-176
Taspine is a bioactive aporphine alkaloid, which has many potent pharmacological effects. A simple, rapid HPLC method to quantify taspine in mouse plasma and tissue homogenates containing either taspine solution or liposome was developed and validate
Publikováno v:
Life Sciences. 78:128-133
Effective components, ligustilide and butylidenephthalide, from Ligusticum Chuanxiong (Ligusticum wallichii Franchat, Umbelliferae) were screened and identified by using a cell membrane chromatography (CMC) and a gas chromatography/mass spectrometry
Publikováno v:
Basic Toxicology. 96:282-288
5-Hydroxytryptamine (5-HT) has been found to elicit enhanced contractile effects in some vascular disorders. The present study was designed to examine if vascular 5-HT 2A receptors are up-regulated during organ culture and if the extracellular signal
Publikováno v:
Journal of separation science. 36(13)
The epidermal growth factor receptors (EGFRs) are significant targets for screening active compounds. In this work, an analytical method was established for rapid screening, separation, and identification of EGFRs antagonists from Curcuma longa. Huma