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Mannose metabolism normalizes gut homeostasis by blocking the TNF-α-mediated proinflammatory circuit.

Autor: Xiao P; Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. tulipxp@zju.edu.cn.; Department of Pathology and Pathophysiology, and Department of Gastroenterology at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. tulipxp@zju.edu.cn.; Immunological Disease Research Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. tulipxp@zju.edu.cn.; Key Laboratory for Immunity and Inflammatory Diseases of Zhejiang Province, Hangzhou, China. tulipxp@zju.edu.cn., Hu Z; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China., Lang J; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China., Pan T; Department of General Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Mertens RT; Department of Immunology, Harvard Medical School, Boston, MA, USA., Zhang H; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China., Guo K; Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.; Immunological Disease Research Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China., Shen M; Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.; Immunological Disease Research Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China., Cheng H; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China., Zhang X; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China., Cao Q; Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. caoq@zju.edu.cn.; Immunological Disease Research Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. caoq@zju.edu.cn., Ke Y; Department of Pathology and Pathophysiology, and Department of Gastroenterology at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China. yke@zju.edu.cn.; Department of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China. yke@zju.edu.cn.; Zhejiang Laboratory for Systems and Precision Medicine, Zhejiang University Medical Center, Hangzhou, China. yke@zju.edu.cn.

Publikováno v: Cellular & molecular immunology [Cell Mol Immunol] 2023 Feb; Vol. 20 (2), pp. 119-130. Date of Electronic Publication: 2022 Dec 05.