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Akademický článek

Artificial intelligence assisted diagnosis of early tc markers and its application

Autor: Laney Zhang, Chinting Wong, Yungeng Li, Tianyi Huang, Jiawen Wang, Chenghe Lin

Publikováno v: Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Thyroid cancer (TC) is a common endocrine malignancy with an increasing incidence worldwide. Early diagnosis is particularly important for TC patients, because it allows patients to receive treatment as early as possible. Artificial intellig

Externí odkaz: https://doaj.org/article/48ef5609ca694d9c9de25f6f13160f6e

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Akademický článek

Application of thyroglobulin and anti-thyroglobulin antibody combined with emission computed tomography in the adjuvant diagnosis of differentiated thyroid carcinoma

Autor: Nan Jiang, Benzheng Jiao, Laney Zhang, Jialong Li, Yungeng Li, Chenghe Lin

Publikováno v: Annals of Medicine, Vol 55, Iss 1 (2023)

AbstractPurpose Thyroid nodules are a kind of common endocrine system disease, with approximately 5% of them developing into malignant lesions, the most common of which belong to differentiated thyroid carcinoma (DTC). Accurate differential diagnosis

Externí odkaz: https://doaj.org/article/32b46384f5ed4923a12e9abeee39b64c

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Akademický článek

Identification of HMMR as a prognostic biomarker for patients with lung adenocarcinoma via integrated bioinformatics analysis

Autor: Zhaodong Li, Hongtian Fei, Siyu Lei, Fengtong Hao, Lijie Yang, Wanze Li, Laney Zhang, Rui Fei

Publikováno v: PeerJ, Vol 9, p e12624 (2021)

Background Lung adenocarcinoma (LUAD) is the most prevalent tumor in lung carcinoma cases and threatens human life seriously worldwide. Here we attempt to identify a prognostic biomarker and potential therapeutic target for LUAD patients. Methods Dif

Externí odkaz: https://doaj.org/article/775be24988ba425bb17c84f228c87702

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Exosomal circular RNA hsa_circ_007293 promotes proliferation, migration, invasion, and epithelial–mesenchymal transition of papillary thyroid carcinoma cells through regulation of the microRNA-653-5p/paired box 6 axis

Autor: Qiuyu Lin, Qianle Qi, Sen Hou, Zhen Chen, Nan Jiang, Laney Zhang, Chenghe Lin

Publikováno v: Bioengineered, Vol 12, Iss 2, Pp 10136-10149 (2021)
Bioengineered
article-version (VoR) Version of Record

Circular RNAs (circRNAs) or exosomes have been reported to exert key regulatory and/or communication functions in human cancer. Nevertheless, current literature on the effects of exosomal circRNAs on tumor invasion and metastasis in thyroid cancer is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cd5de7ab58c43bd81af3badfa00dbe
https://doaj.org/article/8d9ac17267514524a0181bca56311092

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Activation of the TGF-β1/Smad signaling by KIF2C contributes to the malignant phenotype of thyroid carcinoma cells

Autor: Qiuyu Lin, Chenghe Lin, Qian-Le Qi, Nan Jiang, Zhen Chen, Laney Zhang, Sen Hou

Publikováno v: Tissuecell. 73

Kinesin family member 2C (KIF2C) has been identified as a potential oncogene in various types of human cancers; however, the role of KIF2C in thyroid cancer has not yet been elucidated. Quantitative real-time polymerase chain reaction and western blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08acaaa67f4b7a3e668b94319187ecc8
https://pubmed.ncbi.nlm.nih.gov/34624565

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Silencing of AHNAK2 restricts thyroid carcinoma progression by inhibiting the Wnt/β-catenin pathway

Autor: Sen Hou, Chenghe Lin, Qian-Le Qi, Nan Jiang, Qiuyu Lin, Laney Zhang, Zhen Chen

Publikováno v: Neoplasma. 68(5)

AHNAK nucleoprotein 2 (AHNAK2) has been proposed to have an oncogenic role in various human cancers. However, the functional role of AHNAK2 in thyroid carcinoma (TC) progression has never been explored. In this study, quantitative real-time polymeras

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e21c76dac85ba36c3973500f234da09
https://pubmed.ncbi.nlm.nih.gov/34374294

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LncRNA PVT1 Acts as a Tumor Promoter in Thyroid Cancer and Promotes Tumor Progression by Mediating miR-423-5p-PAK3

Autor: Chenghe Lin, Hongguang Zhao, Qiuyu Lin, Qian-Le Qi, Sen Hou, Laney Zhang, Zhen Chen

Publikováno v: Cancer Management and Research

Qiu-Yu Lin,1,* Qian-Le Qi,1,* Sen Hou,1 Zhen Chen,2 Laney Zhang,3 Hong-Guang Zhao,1 Cheng-He Lin1 1Nuclear Medicine Department, The First Hospital of Jilin University, Changchun City 130000, Jilin Province, People’s Republic of China; 2Chengdu Xink

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c70aea457fd60434cf9822e70623bf5
https://www.dovepress.com/lncrna-pvt1-acts-as-a-tumor-promoter-in-thyroid-cancer-and-promotes-tu-peer-reviewed-article-CMAR

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Overexpression of serum lncRNA-ABHD11-AS1 as poor prognosis of patients with papillary thyroid carcinoma

Autor: Laney Zhang, Chenghe Lin, Sen Hou, Qiuyu Lin, Hongguang Zhao, Yu-Ying Zhuang, Zhen Chen

Publikováno v: Experimental and Molecular Pathology. 121:104658

This paper was aimed at exploring the correlation of long non-coding RNA (lncRNA)-ABHD11 Antisense RNA1 (ABHD11-AS1) with the poor prognosis of patients with papillary thyroid carcinoma (PTC) and at investigating its effects on the survival of PTC ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3682ec091e39529e350d9077fde4f500
https://doi.org/10.1016/j.yexmp.2021.104658

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Akademický článek

Silencing of AHNAK2 restricts thyroid carcinoma progression by inhibiting the Wnt/β-catenin pathway.

Autor: Qiu-Yu LIN, Qian-Le QI, Sen HOU, Zhen CHEN, Nan JIANG, Laney ZHANG, Cheng-He LIN

Publikováno v: Neoplasma; 2021, Vol. 68 Issue 5, p1063-1071, 9p

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