Destabilization of chromosome structure by histone H3 lysine 27 methylation.

Autor: Mareike Möller, Klaas Schotanus, Jessica L Soyer, Janine Haueisen, Kathrin Happ, Maja Stralucke, Petra Happel, Kristina M Smith, Lanelle R Connolly, Michael Freitag, Eva H Stukenbrock

Publikováno v: PLoS Genetics, Vol 15, Iss 4, p e1008093 (2019)

Chromosome and genome stability are important for normal cell function as instability often correlates with disease and dysfunction of DNA repair mechanisms. Many organisms maintain supernumerary or accessory chromosomes that deviate from standard ch

Externí odkaz: https://doaj.org/article/c058d309a16c4ae3b8ba6dcc358d662a

The Fusarium graminearum histone H3 K27 methyltransferase KMT6 regulates development and expression of secondary metabolite gene clusters.

Autor: Lanelle R Connolly, Kristina M Smith, Michael Freitag

Publikováno v: PLoS Genetics, Vol 9, Iss 10, p e1003916 (2013)

The cereal pathogen Fusarium graminearum produces secondary metabolites toxic to humans and animals, yet coordinated transcriptional regulation of gene clusters remains largely a mystery. By chromatin immunoprecipitation and high-throughput DNA seque

Externí odkaz: https://doaj.org/article/e2c8db3731dc4c2a9a0e666ea141e6f9

Destabilization of chromosome structure by histone H3 lysine 27 methylation

Autor: Petra Happel, Janine Haueisen, Kristina M. Smith, Maja Stralucke, Lanelle R. Connolly, Jessica L Soyer, Klaas Schotanus, Michael Freitag, Mareike Möller, Eva H. Stukenbrock, Kathrin Happ

Publikováno v: PLoS Genetics, Vol 15, Iss 4, p e1008093 (2019)
PLoS Genetics
Plos Genetics 4 (15), . (2019)
PLoS Genetics, Public Library of Science, 2019, 15 (4), ⟨10.1371/journal.pgen.1008093⟩

Chromosome and genome stability are important for normal cell function as instability often correlates with disease and dysfunction of DNA repair mechanisms. Many organisms maintain supernumerary or accessory chromosomes that deviate from standard ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6231bbf09e820b44601fb774a282b5df
https://doaj.org/article/c058d309a16c4ae3b8ba6dcc358d662a

Application of the Cre/lox System to Construct Auxotrophic Markers for Quantitative Genetic Analyses in Fusarium graminearum

Autor: Lanelle R, Connolly, Allyson A, Erlendson, Corinne M, Fargo, Kendra K, Jackson, Morgan M G, Pelker, Jacob W, Mazzola, Mark S, Geisler, Michael, Freitag

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1848

The bacteriophage P1 Cre/lox system has been utilized in diverse fungi for marker recycling and exchange, generation of targeted chromosome translocations, and targeted deletion of interstitial chromosome segments. Here we show the application of thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::195430f430aa1852e8be13c4d127701b
https://pubmed.ncbi.nlm.nih.gov/30182239

Structural reorganization of the fungal endoplasmic reticulum upon induction of mycotoxin biosynthesis

Autor: Karen Broz, Samuel O. Purvine, Marike Johanne Boenisch, Lanelle R. Connolly, Carrie D. Nicora, H. C. Kistler, William B. Chrisler, Scott E. Baker, Michael Freitag

Publikováno v: Scientific Reports

Compartmentalization of metabolic pathways to particular organelles is a hallmark of eukaryotic cells. Knowledge of the development of organelles and attendant pathways under different metabolic states has been advanced by live cell imaging and organ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9595ec7d4e241dde743116335d9a261c
https://pubmed.ncbi.nlm.nih.gov/28287158