Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Lane R Bushman"'
Autor:
Xinhui Chen, Sharon M Seifert, Jose R Castillo-Mancilla, Lane R Bushman, Jia-Hua Zheng, Jennifer J Kiser, Samantha MaWhinney, Peter L Anderson
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165505 (2016)
The coformulation of the nucleos(t)ide analogs (NA) tenofovir (TFV) disoproxil fumarate (TDF) and emtricitabine (FTC) is approved for HIV-infection treatment and prevention. Plasma TFV and FTC undergo complicated hybrid processes to form, accumulate,
Externí odkaz:
https://doaj.org/article/abbc1059f5d64279949d8227827d78cc
Autor:
Andrea R. Thurman, Louise A. Ouattara, Nazita Yousefieh, Peter L. Anderson, Lane R. Bushman, Xi Fang, Homaira Hanif, Meredith Clark, Onkar Singh, Gustavo F. Doncel
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundNew multi-purpose prevention technology (MPT) products are needed to prevent human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV2). In this study, we evaluated a fast-dissolve insert that may be used vaginally or rectall
Externí odkaz:
https://doaj.org/article/a9cd0edaab2c403583152c032fe80051
Autor:
Fernanda P. Pons-Faudoa, Nicola Di Trani, Simone Capuani, Nathanael Hernandez, Anthony M. Wood, Bharti Nehete, Jean Niles, Kathryn A. Shelton, Sarah Kezar, Lane R. Bushman, Corrine Ying Xuan Chua, Michael M. Ittmann, Peter L. Anderson, Pramod N. Nehete, Roberto C. Arduino, Joan E. Nichols, Alessandro Grattoni
Publikováno v:
Journal of Controlled Release. 358:116-127
Autor:
Mark A. Marzinke, Jessica M. Fogel, Zhe Wang, Estelle Piwowar-Manning, Ryan Kofron, Amber Moser, Pradip Bhandari, Ryann Gollings, Lane R. Bushman, Lei Weng, Elias K. Halvas, John Mellors, Peter L. Anderson, Deborah Persaud, Craig W. Hendrix, Marybeth McCauley, Alex R. Rinehart, Marty St Clair, Susan L. Ford, James F. Rooney, Adeola Adeyeye, Suwat Chariyalertsak, Kenneth Mayer, Roberto C. Arduino, Myron S. Cohen, Beatriz Grinsztejn, Brett Hanscom, Raphael J. Landovitz, Susan H. Eshleman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
HPTN 083 demonstrated that injectable cabotegravir (CAB) was superior to oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for HIV prevention in cisgender men and transgender women who have sex with men. We previously analyzed 58 infections
Autor:
Fernanda P. Pons-Faudoa, Nicola Di Trani, Simone Capuani, Jocelyn Nikita Campa-Carranza, Bharti Nehete, Suman Sharma, Kathryn A. Shelton, Lane R. Bushman, Farah Abdelmawla, Martin Williams, Laura Roon, David Nerguizian, Corrine Ying Xuan Chua, Michael M. Ittmann, Joan E. Nichols, Jason T. Kimata, Peter L. Anderson, Pramod N. Nehete, Roberto C. Arduino, Alessandro Grattoni
The impact of pre-exposure prophylaxis (PrEP) on slowing the global human immunodeficiency virus (HIV) epidemic hinges on effective drugs and delivery platforms. Oral regimens have represented the pillar of HIV PrEP for years. However, variable adher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc6f5977b5e5160d73f8c398006cf28
https://doi.org/10.1101/2022.12.15.520646
https://doi.org/10.1101/2022.12.15.520646
Autor:
Fernanda P. Pons-Faudoa, Nicola Di Trani, Antons Sizovs, Kathryn A. Shelton, Zoha Momin, Lane R. Bushman, Jiaqiong Xu, Dorothy E. Lewis, Sandra Demaria, Trevor Hawkins, James F. Rooney, Mark A. Marzinke, Jason T. Kimata, Peter L. Anderson, Pramod N. Nehete, Roberto C. Arduino, K. Jagannadha Sastry, Alessandro Grattoni
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 981 (2020)
HIV-1 is a chronic disease managed by strictly adhering to daily antiretroviral therapy (ART). However, not all people living with HIV-1 have access to ART, and those with access may not adhere to treatment regimens increasing viral load and disease
Externí odkaz:
https://doaj.org/article/bc54b683a78a4c54871a1a7b1e376c61
Autor:
Cricket Nemkov, Mary Morrow, Jenna Yager, Kristina M Brooks, Jose R Castillo-Mancilla, Jennifer J. Kiser, Peter L. Anderson, Mustafa E Ibrahim, Samantha MaWhinney, Lane R. Bushman, Skyler Peterson
Publikováno v:
AIDS. 35:2481-2487
OBJECTIVE Tenofovir alafenamide (TAF) preferentially loads peripheral blood mononuclear cells (PBMC), resulting in higher PBMC tenofovir-diphosphate (TFV-DP) vs. tenofovir disoproxil fumarate (TDF). No studies have yet compared TFV-DP in PBMC from lo
Autor:
Eitan Grinsteiner, Mary Morrow, Samantha Mawhinney, Ryan P. Coyle, Stacey S. Coleman, Jia-Hua Zheng, Lucas Ellison, Lane R. Bushman, Jennifer J. Kiser, Peter L. Anderson, Jose R. Castillo-Mancilla
Publikováno v:
AIDS research and human retroviruses.
The potency of modern antiretroviral therapy (ART) allows for greater forgiveness to missed doses while still achieving, and maintaining, viral suppression. However, imperfect ART adherence, even if sufficient to maintain viral suppression, has been
Autor:
Peter L. Anderson, Laura Saba, Jenna Yager, Lane R. Bushman, Samantha MaWhinney, Jose R Castillo-Mancilla, Jennifer J. Kiser, Mustafa E Ibrahim, Kristina M Brooks
Publikováno v:
AIDS Res Hum Retroviruses
Tenofovir diphosphate (TFV-DP) concentrations measured with dried blood spots (DBS) can be used to classify adherence to emtricitabine/tenofovir disoproxil fumarate (F/TDF) for HIV pre-exposure prophylaxis (PrEP). A TFV-DP of 700 fmol/punch was previ
Publikováno v:
Journal of Chromatography B. 1223:123725