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Autor:
Junqiao Jia, Tarek Hilal, Katherine E. Bohnsack, Aleksandar Chernev, Ning Tsao, Juliane Bethmann, Aruna Arumugam, Lane Parmely, Nicole Holton, Bernhard Loll, Nima Mosammaparast, Markus T. Bohnsack, Henning Urlaub, Markus C. Wahl
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
ASCC3 is a multi-functional helicase that contains two consecutive Ski2-like helicase units. Here, the authors show that ASCC3 can unwind DNA by threading one strand of a substrate duplex through both helicase units, supported by the TRIP4 protein.
Externí odkaz:
https://doaj.org/article/0ee2586a4c9f44dfb7f3b09d1b9bc981
Autor:
Junqiao Jia, Tarek Hilal, Katherine Bohnsack, Aleksandar Chernev, Ning Tsao, Juliane Schwarz, Aruna Arumugam, Lane Parmely, Nicole Holton, Bernhard Loll, Nima Mosammaparast, Markus Bohnsack, Henning Urlaub, Markus Wahl
Activating signal co-integrator complex (ASCC) supports diverse genome maintenance and gene expression processes. Its ASCC3 subunit is an unconventional nucleic acid helicase, harboring tandem Ski2-like NTPase/helicase cassettes crucial for ASCC func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5b8229d45dddc856d34de5ec3db0875
https://doi.org/10.21203/rs.3.rs-2007381/v1
https://doi.org/10.21203/rs.3.rs-2007381/v1