Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Lane J, Wallace"'
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1002953 (2013)
The basal ganglia is a brain region critically involved in reinforcement learning and motor control. Synaptic plasticity in the striatum of the basal ganglia is a cellular mechanism implicated in learning and neuronal information processing. Therefor
Externí odkaz:
https://doaj.org/article/f11bd862ec2441ab87361e76743ccc3c
Publikováno v:
Synapse (New York, N.Y.)REFERENCES. 73(12)
Published behavioral experiments document that amphetamine-induced increases in locomotor activity are preserved or enhanced in animals with major depletions of stored dopamine but intact dopamine synthesis. Conversely, amphetamine effects are substa
Autor:
Lane J. Wallace, Katherine E. Rooney
Publikováno v:
Synapse. 69:515-525
Dopamine in the striatum signals the saliency of current environmental input and is involved in learned formation of appropriate responses. The regular baseline-firing rate of dopaminergic neurons suggests that baseline dopamine is essential for prop
Autor:
Lane J. Wallace
Full and partial agonists at trace amine-related receptor 1 (TAAR1) have been evaluated in rodent models of stimulant drug use and relapse. Such drugs attenuate the expression of locomotor sensitization to cocaine and methamphetamine and expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d297d375881ebdaa1e6899d2596222cd
https://doi.org/10.1016/b978-0-12-803603-7.00023-9
https://doi.org/10.1016/b978-0-12-803603-7.00023-9
Autor:
Rachel M. Hughes, Lane J. Wallace
Publikováno v:
Synapse. 62:909-919
Results from several experiments monitoring extracellular dopamine (DA) after stimulating axons at high frequencies have been interpreted as evidence for release from two populations of vesicles in dopaminergic varicosities. In addition, these experi
Autor:
Laura E. Connell, Lane J. Wallace
Publikováno v:
Synapse. 62:370-378
Computer simulations of dopamine (DA) and amphetamine interactions associated with dopaminergic storage vesicles were developed in order to better explain how amphetamine causes redistribution of DA out of the vesicles. In the model, DA can be transp
Autor:
Lane J. Wallace
Publikováno v:
Synapse. 61:715-723
Computer simulations of dopamine (DA) regulation at a striatal varicosity were developed to determine basic principles that explain the pattern of changes in level of neurotransmitter and its rate of synthesis and metabolism when DA neuron firing is
Autor:
Katherine E, Rooney, Lane J, Wallace
Publikováno v:
Synapse (New York, N.Y.). 69(11)
Dopamine in the striatum signals the saliency of current environmental input and is involved in learned formation of appropriate responses. The regular baseline-firing rate of dopaminergic neurons suggests that baseline dopamine is essential for prop
Publikováno v:
Behavioural Brain Research. 114:167-174
We have been studying sensitization of psychostimulant-induced stereotyped behavior in mice using both a context-dependent and a context-independent paradigm. In the present study, we tested whether N-methyl-D-aspartate (NMDA) receptor antagonists pr
Publikováno v:
Pharmacology Biochemistry and Behavior. 63:263-269
The present study was designed to determine whether the environmental context in which amphetamine is administered plays a role in the development of sensitization to the stereotyped behavioral effects of amphetamine in mice. In male CF-1 mice, the d