Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Landon M Keele"'
Autor:
Suneel Gupta, Michael K. Fink, Duraisamy Kempuraj, Nishant R. Sinha, Lynn M. Martin, Landon M. Keele, Prashant R. Sinha, Elizabeth A. Giuliano, Nathan P. Hesemann, Sudhanshu P. Raikwar, Shyam S. Chaurasia, Rajiv R. Mohan
Publikováno v:
Mol Ther
Previously we found that inhibitor of differentiation 3 (Id3) gene, a transcriptional repressor, efficiently inhibits corneal keratocyte differentiation to myofibroblasts in vitro. This study evaluated the potential of adeno-associated virus 5 (AAV5)
Autor:
Jason T. Rodier, Landon M Keele, Nathan P. Hesemann, Prashant R Sinha, Suneel Gupta, Lynn M Martin, James R Landreneau, Rajiv R. Mohan, Nishant Sinha
Publikováno v:
Translational Vision Science & Technology
Purpose Tissue-targeted localized BMP7+HGF genes delivered into the stroma via nanoparticle effectively treats corneal fibrosis and rehabilitates transparency in vivo without acute toxicity. This study evaluated the long-term safety and tolerability