Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Landon G Vom Steeg"'
Autor:
Landon G Vom Steeg, Santosh Dhakal, Yishak A Woldetsadik, Han-Sol Park, Kathleen R Mulka, Emma C Reilly, David J Topham, Sabra L Klein
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008506 (2020)
Circulating androgens can modulate immune cell activity, but the impact of androgens on viral pathogenesis remains unclear. Previous data demonstrate that testosterone reduces the severity of influenza A virus (IAV) infection in male mice by mitigati
Externí odkaz:
https://doaj.org/article/89744cb61790481ab2a3a0f23f56794d
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Since CD4+ T cells are essential for regulating adaptive immune responses and for long lasting mucosal protection, changes in CD4+ T cell numbers and function are likely to affect protective immunity. What remains unclear is whether CD4+ T cell compo
Externí odkaz:
https://doaj.org/article/d5ec72daeb384a47b9b3b5980534d739
Autor:
Landon G vom Steeg, Sabra L Klein
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005374 (2016)
Externí odkaz:
https://doaj.org/article/fe4736f8f9ec4269813bc5e5f64a4209
Autor:
Meghan S. Vermillion, Rebecca L. Ursin, Denise I. T. Kuok, Landon G. vom Steeg, Nicholas Wohlgemuth, Olivia J. Hall, Ashley L. Fink, Eric Sasse, Andrew Nelson, Roland Ndeh, Sharon McGrath-Morrow, Wayne Mitzner, Michael C. W. Chan, Andrew Pekosz, Sabra L. Klein
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-12 (2018)
Abstract Background Amphiregulin (AREG) is an epidermal growth factor that is a significant mediator of tissue repair at mucosal sites, including in the lungs during influenza A virus (IAV) infection. Previous research illustrates that males of repro
Externí odkaz:
https://doaj.org/article/4597e7cc17e9456eaaa7c5abe1b54238
Publikováno v:
Vaccine
In both preclinical animal studies and human clinical trials, adult females tend to develop greater adaptive immune responses than males following receipt of either viral or bacterial vaccines. While there is currently no approved malaria vaccine, se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb15061172fea8d30f3ae26abab122ef
https://doi.org/10.1016/j.vaccine.2019.06.075
https://doi.org/10.1016/j.vaccine.2019.06.075
Autor:
Landon G. vom Steeg, Sabra L. Klein
Publikováno v:
Seminars in Immunopathology. 41:189-194
Males and females differ in the outcome of influenza A virus (IAV) infections, which depends significantly on age. During a typical seasonal influenza epidemic, young children (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8547b3f7032a8c29171119d788f08cc1
https://doi.org/10.1007/s00281-018-0718-5
https://doi.org/10.1007/s00281-018-0718-5
Publikováno v:
Cell Immunol
The severity of influenza increases with age, with worse disease in aged males than females. Testosterone concentrations decline with age in males, which may impact influenza pathogenesis. Aged male mice were treated with testosterone or placebo and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe62167cbb3a99a9ee7a5a518ffdbf6
https://europepmc.org/articles/PMC6876866/
https://europepmc.org/articles/PMC6876866/
Autor:
Sabra L. Klein, Harish Narasimhan, Landon G. vom Steeg, Tanvi Potluri, Santosh Dhakal, Meghan S. Vermillion, Sharvari Deshpande, Ashley L. Fink, Kristyn E. Sylvia
Publikováno v:
npj Vaccines, Vol 4, Iss 1, Pp 1-12 (2019)
NPJ Vaccines
NPJ Vaccines
Vaccine-induced immunity declines with age, which may differ between males and females. Using human sera collected before and 21 days after receipt of the monovalent A/Cal/09 H1N1 vaccine, we evaluated cytokine and antibody responses in adult (18–4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229ba40aa89777a700d8b513b2a00edf
https://doi.org/10.1038/s41541-019-0124-6
https://doi.org/10.1038/s41541-019-0124-6
Autor:
Santosh Dhakal, Landon G. vom Steeg, Kathleen R. Mulka, Sabra L. Klein, Yishak A. Woldetsadik, Han Sol Park, David J. Topham, Emma C. Reilly
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008506 (2020)
PLoS Pathogens
PLoS Pathogens
Circulating androgens can modulate immune cell activity, but the impact of androgens on viral pathogenesis remains unclear. Previous data demonstrate that testosterone reduces the severity of influenza A virus (IAV) infection in male mice by mitigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d002952925f59b19b45a1474c2c47e89
https://doi.org/10.1371/journal.ppat.1008506
https://doi.org/10.1371/journal.ppat.1008506
Autor:
Denise I. T. Kuok, Meghan S. Vermillion, Nicholas Wohlgemuth, Andrew Nelson, Olivia J. Hall, Ashley L. Fink, Roland Ndeh, Sharon A. McGrath-Morrow, Wayne Mitzner, Landon G. vom Steeg, Michael C. W. Chan, Eric Sasse, Andrew Pekosz, Sabra L. Klein, Rebecca L. Ursin
Publikováno v:
Biology of Sex Differences
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-12 (2018)
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-12 (2018)
Background Amphiregulin (AREG) is an epidermal growth factor that is a significant mediator of tissue repair at mucosal sites, including in the lungs during influenza A virus (IAV) infection. Previous research illustrates that males of reproductive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba9e98649dbe4f47c9e018377f2437b
https://doi.org/10.1186/s13293-018-0184-8
https://doi.org/10.1186/s13293-018-0184-8