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Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro

Autor: Hsia, K, Yang, M-J, Chen, W-M, Yao, C-L, Lin, C-H, Loong, C-C, Huang, Y-L, Lin, Y-T, Lander, AD, Lee, H, Lu, J-H

Publikováno v: Hsia, K; Yang, M-J; Chen, W-M; Yao, C-L; Lin, C-H; Loong, C-C; et al.(2017). Sphingosine-1-phosphate improves endothelialization with reduction of thrombosis in recellularized human umbilical vein graft by inhibiting syndecan-1 shedding in vitro. ACTA BIOMATERIALIA, 51, 341-350. doi: 10.1016/j.actbio.2017.01.050. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9ts7q9k6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::76c77cc889aaf2c2e3ef2ec0e29180e1
http://www.escholarship.org/uc/item/9ts7q9k6

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Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: Abstracts from the 2014 Scientific and Educational Symposium

Publikováno v: Kline, AD; Calof, AL; Lander, AD; Gerton, JL; Krantz, ID; Dorsett, D; et al.(2015). Clinical, developmental and molecular update on Cornelia de Lange syndrome and the cohesin complex: Abstracts from the 2014 Scientific and Educational Symposium. American Journal of Medical Genetics, Part A, 167(6), 1179-1192. doi: 10.1002/ajmg.a.37056. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6d17547n

© 2015 Wiley Periodicals, Inc. Cornelia de Lange Syndrome (CdLS) is the most common example of disorders of the cohesin complex, or cohesinopathies. There are a myriad of clinical issues facing individuals with CdLS, particularly in the neurodevelop

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The Role of NIPBL in Cornelia de Lange Syndrome

Autor: Newkirk, DA, Chen, YY, Flowers, E, Zeng, X, Kong, X, Yao, C, Ball, A, Kawauchi, S, Santos, R, Calof, AL, Lander, AD, Shi, Y, Xie, X, Yokomori, K

Publikováno v: Newkirk, DA; Chen, YY; Flowers, E; Zeng, X; Kong, X; Yao, C; et al.(2015). The Role of NIPBL in Cornelia de Lange Syndrome. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4qk83049

Cornelia de Lange Syndrome (CdLS) is a severe developmental disorder frequently associated with heterozygous loss-of-function NIPBL mutations. NIPBL loads cohesin onto chromatin. Cohesin mediates sister chromatid cohesion important for mitosis, but i

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Abnormalities of Limb Development in Vertebrate Animal Models of CdLS

Autor: Calof, AL, Muto, A, Lopez-Burks, ME, Schilling, T, Lander, AD

Publikováno v: Calof, AL; Muto, A; Lopez-Burks, ME; Schilling, T; & Lander, AD. (2015). Abnormalities of Limb Development in Vertebrate Animal Models of CdLS. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/95f47511

Recent studies implicate the cohesin complex in transcriptional control, potentially through influences on long-distance communication between DNA elements. Animal models of Cornelia de Lange Syndrome (CdLS), the most common “cohesinopathy,” prov

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Generation, differentiation, and maturation of olfactory receptor neurons in vitro

Autor: Calof, AL, Adusumalli, MD, DeHamer, MK, Guevara, JL, Mumm, JS, Whitehead, SJ, Lander, AD

Publikováno v: Calof, AL; Adusumalli, MD; DeHamer, MK; Guevara, JL; Mumm, JS; Whitehead, SJ; et al.Kurihara, K; Suzuki, N; & Ogawa, H eds. (2013). Generation, differentiation, and maturation of olfactory receptor neurons in vitro. In Olfaction and Taste XI Proceedings of the 11th International Symposium on Olfaction and Taste and of the 27th Japanese Symposium on Taste and Smell Joint Meeting held at Kosei-nenkin Kaikan, Sapporo, Japan, July 12–16, 1993. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8f12632z

Proceedings of the 11th International Symposium on Olfaction and Taste and of the 27th Japanese Symposium on Taste ... In compiling the proceedings of this conference into the book entitled “Olfaction and Taste XI”, the papers presented at...

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Elaboration of a multispecies model of solid tumor growth with tumor-host interactions

Autor: Konstorum, A, Sprowl, SA, Waterman, ML, Lander, AD, Lowengrub, JS

Publikováno v: Lander, AD; Konstorum, A; Sprowl, SA; Waterman, ML; & Lowengrub, JS. (2013). Elaboration of a multispecies model of solid tumor growth with tumor-host interactions. Proc. 3rd Int. Conf. Appl. Nonlinear Dynamics. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/62p9847h

There has been increasing evidence of the critical effects of microenvironmental influence on tumor growth and metastasis. In this report, we extend a multispecies continuum model of solid tumor growth to include interaction of the tumor with its mic

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Genetic interactions of cell intrinsic factors and secreted signals regulate neurogenesis in olfactory epithelium / 細胞内因子と分泌シグナル因子の反作用による嗅覚上皮神経発生の制御

Autor: Muto, A, Shimako, K, Santos, R, Kim, J, Gokoffski, KK, Wu, HH, Lander, AD, Calof, AL

Publikováno v: Muto, A; Shimako, K; Santos, R; Kim, J; Gokoffski, KK; Wu, HH; et al.(2012). Genetic interactions of cell intrinsic factors and secreted signals regulate neurogenesis in olfactory epithelium / 細胞内因子と分泌シグナル因子の反作用による嗅覚上皮神経発生の制御. Nihon Aji to Nioi Gakkai.: Journal for the Japanese Association for Study of Taste and Smell, 19(1), 57-62. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6891p5gj

我々はこれまでに、TGF 一βファミリーの分泌因子である Gdf11 や Activinβ B が嗅覚上皮の発生を負に制御することを見出した。さらに、転写因了一Foxg1 が TGF 一βフ �

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Adhesion of B lymphoid (MPC-11) cells to type I collagen is mediated by integral membrane proteoglycan, syndecan

Autor: Sanderson, RD, Sneed, TB, Young, LA, Sullivan, GL, Lander, AD

Publikováno v: Sanderson, RD; Sneed, TB; Young, LA; Sullivan, GL; & Lander, AD. (1992). Adhesion of B lymphoid (MPC-11) cells to type I collagen is mediated by integral membrane proteoglycan, syndecan.. Journal of immunology (Baltimore, Md. : 1950), 148(12), 3902-3911. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/07b3647k

Differentiating B lymphocytes undergo changes in cell-cell and cell-matrix adhesion that control their movement through a series of distinct microenvironments. The integral membrane proteoglycan, syndecan, is a candidate for mediating B lymphocyte-ma

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https://doi.org/10.4049/jimmunol.148.12.3902

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Distributed individual-based simulation

Autor: Liu, J, Dillencourt, MB, Bic, LF, Gillen, D, Lander, AD

Publikováno v: Liu, J; Dillencourt, MB; Bic, LF; Gillen, D; & Lander, AD. (2009). Distributed individual-based simulation. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 5704 LNCS, 590-601. doi: 10.1007/978-3-642-03869-3_56. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/34b5g76g

Individual-based simulations are an important class of applications where a complex system is modeled as a collection of autonomous entities, each having its own identify and behavior in the underlying simulated space. The main drawback of such simul

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