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Akademický článek

Analysis of positional candidate genes in the AAA1 susceptibility locus for abdominal aortic aneurysms on chromosome 19

Autor: Ferrell Robert E, Sakalihasan Natzi, Igo Robert P, Lu Qing, Li Ming, Lenk Guy M, Tromp Gerard, Kyo Yoshiki, Lillvis John H, Schworer Charles M, Gatalica Zoran, Land Susan, Kuivaniemi Helena

Publikováno v: BMC Medical Genetics, Vol 12, Iss 1, p 14 (2011)

Abstract Background Abdominal aortic aneurysm (AAA) is a complex disorder with multiple genetic risk factors. Using affected relative pair linkage analysis, we previously identified an AAA susceptibility locus on chromosome 19q13. This locus has been

Externí odkaz: https://doaj.org/article/0728e94b465d46dd8f0100a393a92d47

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Akademický článek

Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures

Autor: Studzinski Diane, Nedelkoska Liljana, Bealmear Beverly, Benjamins Joyce A, Lisak Robert P, Retland Ernest, Yao Bin, Land Susan

Publikováno v: Journal of Neuroinflammation, Vol 6, Iss 1, p 4 (2009)

Abstract Background Cytokines secreted by immune cells and activated glia play central roles in both the pathogenesis of and protection from damage to the central nervous system (CNS) in multiple sclerosis (MS). Methods We have used gene array analys

Externí odkaz: https://doaj.org/article/698dec5efd4147959ac2ebdfc0be6d7b

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Akademický článek

Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for glial and neural-related molecules in central nervous system mixed glial cell cultures: neurotrophins, growth factors and structural proteins

Autor: Nedelkoska Liljana, Bealmear Beverly, Benjamins Joyce A, Lisak Robert P, Yao Bin, Land Susan, Studzinski Diane

Publikováno v: Journal of Neuroinflammation, Vol 4, Iss 1, p 30 (2007)

Abstract Background In multiple sclerosis, inflammatory cells are found in both active and chronic lesions, and it is increasingly clear that cytokines are involved directly and indirectly in both formation and inhibition of lesions. We propose that

Externí odkaz: https://doaj.org/article/7db18da0b0f64aea885d681341221f31

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