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Akademický článek
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The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen.
Autor:
McCarthy KA; FORMA Therapeutics, Watertown, MA, USA., Franklin GJ; FORMA Therapeutics, Watertown, MA, USA., Lancia DR Jr; FORMA Therapeutics, Watertown, MA, USA., Olbrot M; FORMA Therapeutics, Watertown, MA, USA., Pardo E; FORMA Therapeutics, Watertown, MA, USA.; Relay Therapeutics, Cambridge, MA, USA., O'Connell JC; FORMA Therapeutics, Watertown, MA, USA., Kollmann CS; FORMA Therapeutics, Watertown, MA, USA.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2020 Jun; Vol. 25 (5), pp. 515-522. Date of Electronic Publication: 2020 Feb 28.
Autor:
Su L; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China., Feng J; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China., Peng T; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China., Wan J; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China., Fan J; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China., Li J; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China., O'Connell J; FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Lancia DR Jr; FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Franklin GJ; FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Liu G; Discovery Chemistry Unit , HitGen Inc. , Building 6, No. 8 Huigu First East Road , Tianfu International Bio-Town, Shuangliu District, Chengdu 610200 , Sichuan , People's Republic of China.
Publikováno v:
Organic letters [Org Lett] 2020 Feb 21; Vol. 22 (4), pp. 1290-1294. Date of Electronic Publication: 2020 Jan 30.
Autor:
Lin J; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Lu W; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Caravella JA; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Campbell AM; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Diebold RB; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Ericsson A; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Fritzen E; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Gustafson GR; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Lancia DR Jr; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Shelekhin T; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Wang Z; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Castro J; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Clarke A; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Gotur D; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Josephine HR; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Katz M; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Diep H; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Kershaw M; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Yao L; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Kauffman G; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Hubbs SE; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Luke GP; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Toms AV; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Wang L; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Bair KW; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Barr KJ; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Dinsmore C; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Walker D; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Ashwell S; Forma Therapeutics, Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2019 Jul 25; Vol. 62 (14), pp. 6575-6596. Date of Electronic Publication: 2019 Jul 08.
Autor:
Martin MW; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA. Electronic address: mmartin@formatherapeutics.com., Lancia DR Jr; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Li H; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., Schiller SER; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Toms AV; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Wang Z; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Bair KW; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Castro J; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Fessler S; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Gotur D; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Hubbs SE; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., Kauffman GS; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., Kershaw M; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., Luke GP; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., McKinnon C; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Yao L; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., Lu W; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Millan DS; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Apr 15; Vol. 29 (8), pp. 1001-1006. Date of Electronic Publication: 2019 Feb 11.
Autor:
Faver JC, Riehle K, Lancia DR Jr; FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Milbank JBJ; FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Kollmann CS; FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States., Simmons N, Yu Z, Matzuk MM
Publikováno v:
ACS combinatorial science [ACS Comb Sci] 2019 Feb 11; Vol. 21 (2), pp. 75-82. Date of Electronic Publication: 2019 Jan 23.
Autor:
Martin MW; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA. Electronic address: mmartin@formatherapeutics.com., Lee JY; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Lancia DR Jr; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Ng PY; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Han B; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Thomason JR; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Lynes MS; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Marshall CG; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Conti C; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Collis A; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Morales MA; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Doshi K; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Rudnitskaya A; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA., Yao L; FORMA Therapeutics, 35 Northeast Industrial Road, Branford, CT 06405, USA., Zheng X; FORMA Therapeutics, 500 Arsenal Street, Suite 100, Watertown, MA 02472, USA.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Jul 01; Vol. 28 (12), pp. 2143-2147. Date of Electronic Publication: 2018 May 09.
Autor:
Turnbull AP; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Ioannidis S; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Krajewski WW; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Heride C; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Martin ACL; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Tonkin LM; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Townsend EC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Buker SM; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Lancia DR; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Caravella JA; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Toms AV; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Charlton TM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Lahdenranta J; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Wilker E; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Follows BC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Evans NJ; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Stead L; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Alli C; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Zarayskiy VV; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Talbot AC; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Buckmelter AJ; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Wang M; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., McKinnon CL; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Saab F; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., McGouran JF; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Century H; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Gersch M; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK., Pittman MS; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Marshall CG; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Raynham TM; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Simcox M; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Stewart LMD; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., McLoughlin SB; CRUK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Escobedo JA; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Bair KW; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Dinsmore CJ; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Hammonds TR; CRUK Therapeutic Discovery Laboratories, London Bioscience Innovation Centre, London NW1 0NH, UK., Kim S; FORMA Therapeutics, Arsenal Street, Watertown, Massachusetts 02472, USA., Urbé S; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Clague MJ; Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3BX, UK., Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK., Komander D; Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK.
Publikováno v:
Nature [Nature] 2017 Oct 26; Vol. 550 (7677), pp. 481-486. Date of Electronic Publication: 2017 Oct 18.
Autor:
Kerres N; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Steurer S; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Schlager S; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Bader G; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Berger H; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Caligiuri M; FORMA Therapeutics, Watertown, MA 02472, USA., Dank C; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Engen JR; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA., Ettmayer P; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Fischerauer B; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Flotzinger G; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Gerlach D; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Gerstberger T; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Gmaschitz T; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Greb P; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Han B; FORMA Therapeutics, Watertown, MA 02472, USA., Heyes E; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Iacob RE; Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA., Kessler D; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Kölle H; Boehringer Ingelheim, MedChem, Structural Research, Birkendorfer Str. 65, 88397 Biberach, Germany., Lamarre L; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Lancia DR; FORMA Therapeutics, Watertown, MA 02472, USA., Lucas S; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Mayer M; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Mayr K; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Mischerikow N; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Mück K; Boehringer Ingelheim, MedChem, Structural Research, Birkendorfer Str. 65, 88397 Biberach, Germany., Peinsipp C; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Petermann O; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Reiser U; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Rudolph D; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Rumpel K; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Salomon C; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Scharn D; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Schnitzer R; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Schrenk A; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Schweifer N; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Thompson D; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Traxler E; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Varecka R; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Voss T; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Weiss-Puxbaum A; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Winkler S; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Zheng X; FORMA Therapeutics, Watertown, MA 02472, USA., Zoephel A; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Kraut N; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., McConnell D; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Pearson M; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria., Koegl M; Boehringer Ingelheim RCV GmbH & Co KG, 1221 Vienna, Austria. Electronic address: manfred.koegl@boehringer-ingelheim.com.
Publikováno v:
Cell reports [Cell Rep] 2017 Sep 19; Vol. 20 (12), pp. 2860-2875.