Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Lance L. Munn"'
Autor:
Gabriel Gruionu, James Baish, Sean McMahon, David Blauvelt, Lucian G. Gruionu, Mara Onita Lenco, Benjamin J. Vakoc, Timothy P. Padera, Lance L. Munn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Overly dense microvascular networks are treated by selective reduction of vascular elements. Inappropriate manipulation of microvessels could result in loss of host tissue function or a worsening of the clinical problem. Here, experimental,
Externí odkaz:
https://doaj.org/article/74e1fc27144d46779a5d8f1a2d848d30
Publikováno v:
Advanced Science, Vol 10, Iss 36, Pp n/a-n/a (2023)
Abstract Effective anti‐cancer immune responses require activation of one or more naïve T cells. If the correct naïve T cell encounters its cognate antigen presented by an antigen presenting cell, then the T cell can activate and proliferate. Her
Externí odkaz:
https://doaj.org/article/d5fbc98e2d0542fe95abdabc696c7864
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6 (2023)
Implementation of effective cancer treatment strategies requires consideration of how the spatiotemporal heterogeneities within the tumor microenvironment (TME) influence tumor progression and treatment response. Here, we developed a multi-scale thre
Externí odkaz:
https://doaj.org/article/bfb4e1fd2ec14124bd21f7d16c0e4b7b
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Edema in the limbs can arise from pathologies such as elevated capillary pressures due to failure of venous valves, elevated capillary permeability from local inflammation, and insufficient fluid clearance by the lymphatic system. The most c
Externí odkaz:
https://doaj.org/article/b035c8446d594c8cac422e5ce8a2de18
Autor:
Sonu Subudhi, Ashish Verma, Ankit B. Patel, C. Corey Hardin, Melin J. Khandekar, Hang Lee, Dustin McEvoy, Triantafyllos Stylianopoulos, Lance L. Munn, Sayon Dutta, Rakesh K. Jain
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-7 (2021)
Abstract As predicting the trajectory of COVID-19 is challenging, machine learning models could assist physicians in identifying high-risk individuals. This study compares the performance of 18 machine learning algorithms for predicting ICU admission
Externí odkaz:
https://doaj.org/article/05e8f4be9b9244a0bd5e8c0dcae77ba7
Autor:
Nisha Gupta, Hiroki Ochiai, Yoshinori Hoshino, Sebastian Klein, Jozef Zustin, Rakesh R. Ramjiawan, Shuji Kitahara, Nir Maimon, Despina Bazou, Sarah Chiang, Sen Li, Daniel H. Schanne, Rakesh. K. Jain, Lance L. Munn, Peigen Huang, Sergey V. Kozin, Dan G. Duda
Publikováno v:
Cancers, Vol 15, Iss 4, p 1021 (2023)
Radiotherapy (RT) is a standard treatment for patients with advanced prostate cancer (PCa). Previous preclinical studies showed that SDF1α/CXCR4 axis could mediate PCa metastasis (most often to the bones) and cancer resistance to RT. We found high l
Externí odkaz:
https://doaj.org/article/d57f6001bace48e78201d2fea1a96079
Autor:
Heriberto Moran, Limary M. Cancel, Peigen Huang, Sylvie Roberge, Tuoye Xu, John M. Tarbell, Lance L. Munn
Publikováno v:
Matrix Biology Plus, Vol 13, Iss , Pp 100100- (2022)
Mammalian cells, including cancer cells, are covered by a surface layer containing cell bound proteoglycans, glycoproteins, associated glycosaminoglycans and bound proteins that is commonly referred to as the glycocalyx. Solid tumors also have a dyna
Externí odkaz:
https://doaj.org/article/b4fe6281e97a4dd98c8aedea5bb97eff
Autor:
Sonu Subudhi, Chrysovalantis Voutouri, C. Corey Hardin, Mohammad Reza Nikmaneshi, Ankit B. Patel, Ashish Verma, Melin J. Khandekar, Sayon Dutta, Triantafyllos Stylianopoulos, Rakesh K. Jain, Lance L. Munn
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103809- (2022)
Summary: Background: Mathematical modelling may aid in understanding the complex interactions between injury and immune response in critical illness. Methods: We utilize a system biology model of COVID-19 to analyze the effect of altering baseline pa
Externí odkaz:
https://doaj.org/article/fcb0daa2adf24ad280347e1792d5f361
Autor:
Mohammad Souri, M. Soltani, Farshad Moradi Kashkooli, Mohammad Kiani Shahvandi, Mohsen Chiani, Fatemeh Sadat Shariati, Mohammad Reza Mehrabi, Lance L. Munn
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100208- (2022)
Nanotechnology in medical applications, especially in oncology as drug delivery systems, has recently shown promising results. However, although these advances have been promising in the pre-clinical stages, the clinical translation of this technolog
Externí odkaz:
https://doaj.org/article/0a1c8dee9ff84e248f794e57c3e0480d
Publikováno v:
Applied Sciences, Vol 7, Iss 12, p 1275 (2017)
This paper describes the effects of low intensity continuous ultrasound (LICU) on the inflammatory response of mouse pancreatic tumor explants. While there are many reports focusing on the application of low-intensity pulsed ultrasound (LIPUS) on cel
Externí odkaz:
https://doaj.org/article/6d4d63ea79e94a77b926ad88b419cd2d