Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lance Kaleta"'
Autor:
Luis E. Rodriguez, Gail Bukofzer, Joann P. Palma, Yi-Chun Wang, Keith B. Glaser, Daniel M. Albert, Junling Li, Lance Kaleta, Michael R. Michaelides, Jerry Clarin, Sally Schlessinger, Paul Ellis, Chris Tse, Cherrie K. Donawho
Publikováno v:
Cancer Research. 72:858-858
The Aurora kinases are a family of serine/threonine kinases that mediate essential functions in cell division. Aurora A depletion results in accumulation of cells in the G2/M phase and apoptosis. Inhibition of Aurora B/C results in abnormal cell divi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd1e858d7eeab805bc434a12345177a9
https://doi.org/10.1158/1538-7445.am2012-858
https://doi.org/10.1158/1538-7445.am2012-858
Autor:
Yi-Chun Wang, Debra Montgomery, Jerry Clarin, Sally Schlessinger, Baole Wang, Chris Tse, David Frost, Daniel M. Albert, Paul E. Ellis, Keith B. Glaser, Luis E. Rodriguez, Jennifer J. Bouska, Joann P. Palma, Lance Kaleta, Cherrie K. Donawho, Michael R. Michaelides, Gail Bukofzer
Publikováno v:
Molecular Cancer Therapeutics. 10:B231-B231
The Aurora kinases are a family of serine/threonine kinases that mediate multiple essential functions in cell division. Aurora A depletion results in accumulation of cells in the G2/M phase and apoptosis. Inhibition of Aurora B/C results in abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffe8c09e6c12dfa823d6df0b212e79e5
https://doi.org/10.1158/1535-7163.targ-11-b231
https://doi.org/10.1158/1535-7163.targ-11-b231
Autor:
Paul Ellis, Fritz G. Buchanan, Vincent L. Giranda, Kenneth B. Idler, Robert A. Carr, Gail Bukofzer, Lance Kaleta, Joann P. Palma, Jennifer J. Bouska, Luis E. Rodriguez, Velitchka Bontcheva-Diaz, Alexander R. Shoemaker, Xuesong Liu, David Frost, Cherrie K. Donawho, Thomas D. Penning, Gui-Dong Zhu
Publikováno v:
Molecular Cancer Therapeutics. 10:B62-B62
PARP's role in DNA damage recognition/repair makes PARP inhibition an attractive cancer therapeutic target. Veliparib (ABT-888) is a potent PARP inhibitor with excellent oral bioavailability that readily crosses the blood-brain barrier and is current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ac05c932a6e39baeb46ee46dc7f5997
https://doi.org/10.1158/1535-7163.targ-11-b62
https://doi.org/10.1158/1535-7163.targ-11-b62