Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lance Edward V. Lumahan"'
Publikováno v:
Cells, Vol 13, Iss 2, p 191 (2024)
Androgen receptor (AR) transcriptional activity significantly influences prostate cancer (PCa) progression. In addition to ligand stimulation, AR transcriptional activity is also influenced by a variety of post-translational modifications (PTMs). A n
Externí odkaz:
https://doaj.org/article/ce603bd0ed9046cea9eda4c31d8322f2
Autor:
Xinzhe Yu, Ping Yi, Anil K. Panigrahi, Lance Edward V. Lumahan, John P. Lydon, David M. Lonard, Steven J. Lutdke, Zhao Wang, Bert W. O’Malley
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105321- (2022)
Summary: We report the quaternary structure of core transcriptional complex for the full-length human progesterone receptor-B (PR-B) homodimer with primary coactivator steroid receptor coactivator-2 (SRC-2) and the secondary coactivator p300/CREB-bin
Externí odkaz:
https://doaj.org/article/f16f61a190c24044a867d72e40402e48
Autor:
Ramesh Singh, Huan Meng, Tao Shen, Lance Edward V. Lumahan, Steven Nguyen, Hong Shen, Subhamoy Dasgupta, Li Qin, Dileep Karri, Bokai Zhu, Feng Yang, Cristian Coarfa, Bert W. O’Malley, Ping Yi
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Castration-resistant prostate cancer (CRPC) poses a major clinical challenge with the androgen receptor (AR) remaining to be a critical oncogenic player. Several lines of evidence indicate that AR induces a distinct transcriptional program after andr