Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lance E. Keller"'
Autor:
Courtney D. Thompson, Jessica L. Bradshaw, Wesley S. Miller, Ana G. Jop Vidal, Jorge E. Vidal, Jason W. Rosch, Larry S. McDaniel, Lance E. Keller
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Streptococcus pneumoniae colonizes the human nasopharynx and causes several diseases. Pneumococcal vaccines target the polysaccharide capsule and prevent most serious disease, but there has been an increase in the prevalence of nonencapsulat
Externí odkaz:
https://doaj.org/article/af120e3881874dc086e0fbc86e56abbd
Autor:
Jessica L. Bradshaw, Haley R. Pipkins, Lance E. Keller, James K. Pendarvis, Larry S. McDaniel
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Nonencapsulated Streptococcus pneumoniae (NESp) is an emerging human pathogen that colonizes the nasopharynx and is associated with noninvasive diseases such as otitis media (OM), conjunctivitis, and nonbacteremic pneumonia. Since capsule ex
Externí odkaz:
https://doaj.org/article/c9ed92d5c10549fa84a94ccad8eb8e26
Autor:
Cheshil Dixit, Lance E. Keller, Jessica L. Bradshaw, D. Ashley Robinson, Edwin Swiatlo, Larry S. McDaniel
Publikováno v:
IDCases, Vol 4, Iss C, Pp 56-58 (2016)
Streptococcus pneumoniae is an important human pathogen. To cause disease, it must first colonize the nasopharynx. The widespread use of pneumococcal-conjugate vaccines which target the capsular polysaccharide has led to decreased nasopharyngeal carr
Externí odkaz:
https://doaj.org/article/015c60898c054b8aa63d85f5690a91de
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT While significant protection from pneumococcal disease has been achieved by the use of polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent protection has been limited by serotype replacement along with disease c
Externí odkaz:
https://doaj.org/article/c1d55837a95e46fb85b15f55309543a9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Streptococcus pneumoniae infections result in a range of human diseases and are responsible for almost one million deaths annually. Pneumococcal disease is mediated in part through surface structures and an anti-phagocytic capsule. Recent studies hav
Externí odkaz:
https://doaj.org/article/8f96354a77234542912428ec6681fce2
Autor:
Martín Alcorlo, Mohammed R Abdullah, Leif Steil, Francisco Sotomayor, Laura López-de Oro, Sonia de Castro, Sonsoles Velázquez, Thomas P Kohler, Elisabet Jiménez, Ana Medina, Isabel Usón, Lance E Keller, Jessica L Bradshaw, Larry S McDaniel, María-José Camarasa, Uwe Völker, Sven Hammerschmidt, Juan A Hermoso
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1011883 (2024)
ATP-binding cassette (ABC) transport systems are crucial for bacteria to ensure sufficient uptake of nutrients that are not produced de novo or improve the energy balance. The cell surface of the pathobiont Streptococcus pneumoniae (pneumococcus) is
Externí odkaz:
https://doaj.org/article/b962a379033346788836c4582103dd80
Publikováno v:
The Journal of Infectious Diseases. 217:1637-1644
Background Current Streptococcus pneumoniae vaccines selectively target capsular polysaccharide of specific serotypes, leading to an increase in nonencapsulated S. pneumoniae (NESp). Cocolonization by encapsulated pneumococci and NESp increases the o
Here we describe the creation of three integration vectors, pPEPX, pPEPY and pPEPZ, for use with the opportunistic human pathogenStreptococcus pneumoniae. The constructed vectors, named PEP for Pneumococcal Engineering Platform, employ an IPTG-induci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1238dae1506bba16fdfdb71b04532408
https://doi.org/10.1101/594697
https://doi.org/10.1101/594697
Autor:
D. Ashley Robinson, Lance E. Keller, Justin A. Thornton, Keun-Seok Seo, Larry S. McDaniel, Bo Youn Moon, Xiao Luo
Publikováno v:
Clinical and Vaccine Immunology. 22:1146-1153
Current vaccinations are effective against encapsulated strains of Streptococcus pneumoniae , but they do not protect against nonencapsulated Streptococcus pneumoniae (NESp), which is increasing in colonization and incidence of pneumococcal disease.
Autor:
Jérémie Voumard, Marc Robinson-Rechavi, Michel Schneider, Lance E. Keller, Emanuel Schmid-Siegert, Michel Jaboyedoff, Sandra Calderon, Christian S. Hardtke, Laurent Farinelli, Caroline Gouhier-Darimont, Pietro Cattaneo, Christian Fankhauser, John R. Pannell, Alexandre Reymond, Frédéric Schütz, Marco Pagni, Namrata Sarkar, Christian Iseli, Ioannis Xenarios, Philippe Reymond, Jacqueline Chrast
Publikováno v:
Nature plants. 3(12)
Because plants do not possess a defined germline, deleterious somatic mutations can be passed to gametes, and a large number of cell divisions separating zygote from gamete formation may lead to many mutations in long-lived plants. We sequenced the g