Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lance E Keller"'
Autor:
Martín Alcorlo, Mohammed R Abdullah, Leif Steil, Francisco Sotomayor, Laura López-de Oro, Sonia de Castro, Sonsoles Velázquez, Thomas P Kohler, Elisabet Jiménez, Ana Medina, Isabel Usón, Lance E Keller, Jessica L Bradshaw, Larry S McDaniel, María-José Camarasa, Uwe Völker, Sven Hammerschmidt, Juan A Hermoso
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1011883 (2024)
ATP-binding cassette (ABC) transport systems are crucial for bacteria to ensure sufficient uptake of nutrients that are not produced de novo or improve the energy balance. The cell surface of the pathobiont Streptococcus pneumoniae (pneumococcus) is
Externí odkaz:
https://doaj.org/article/b962a379033346788836c4582103dd80
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179159 (2017)
Streptococcus pneumoniae is commonly found in the human nasopharynx and is the causative agent of multiple diseases. Since invasive pneumococcal infections are associated with encapsulated pneumococci, the capsular polysaccharide is the target of lic
Externí odkaz:
https://doaj.org/article/0fd35a7c9a8c4f27968d6a865da6b444
Autor:
Lindsey R Brown, Steven M Gunnell, Adam N Cassella, Lance E Keller, Lisa A Scherkenbach, Beth Mann, Matthew W Brown, Rebecca Hill, Nicholas C Fitzkee, Jason W Rosch, Elaine I Tuomanen, Justin A Thornton
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146785 (2016)
Across bacterial species, metal binding proteins can serve functions in pathogenesis in addition to regulating metal homeostasis. We have compared and contrasted the activities of zinc (Zn2+)-binding lipoproteins AdcA and AdcAII in the Streptococcus
Externí odkaz:
https://doaj.org/article/18f79d6ba8cb4e208105c3e00e09ee3e
Autor:
Courtney D. Thompson, Jessica L. Bradshaw, Wesley S. Miller, Ana G. Jop Vidal, Jorge E. Vidal, Jason W. Rosch, Larry S. McDaniel, Lance E. Keller
Publikováno v:
mBio. 14
Streptococcus pneumoniae (pneumococcus) can cause a range of diseases. Although there is a robust pneumococcal vaccination program that reduces invasive pneumococcal disease by targeting various polysaccharide capsules, there has been an increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::403f21ce97d7d1ec807fadaf370c3beb
https://doi.org/10.1128/mbio.03325-22
https://doi.org/10.1128/mbio.03325-22
Autor:
Jessica L. Bradshaw, Haley R. Pipkins, Lance E. Keller, James K. Pendarvis, Larry S. McDaniel
Publikováno v:
mBio, Vol 9, Iss 1 (2018)
ABSTRACT Nonencapsulated Streptococcus pneumoniae (NESp) is an emerging human pathogen that colonizes the nasopharynx and is associated with noninvasive diseases such as otitis media (OM), conjunctivitis, and nonbacteremic pneumonia. Since capsule ex
Externí odkaz:
https://doaj.org/article/c9ed92d5c10549fa84a94ccad8eb8e26
Autor:
Cheshil Dixit, Lance E. Keller, Jessica L. Bradshaw, D. Ashley Robinson, Edwin Swiatlo, Larry S. McDaniel
Publikováno v:
IDCases, Vol 4, Iss C, Pp 56-58 (2016)
Streptococcus pneumoniae is an important human pathogen. To cause disease, it must first colonize the nasopharynx. The widespread use of pneumococcal-conjugate vaccines which target the capsular polysaccharide has led to decreased nasopharyngeal carr
Externí odkaz:
https://doaj.org/article/015c60898c054b8aa63d85f5690a91de
Publikováno v:
mBio, Vol 7, Iss 2 (2016)
ABSTRACT While significant protection from pneumococcal disease has been achieved by the use of polysaccharide and polysaccharide-protein conjugate vaccines, capsule-independent protection has been limited by serotype replacement along with disease c
Externí odkaz:
https://doaj.org/article/c1d55837a95e46fb85b15f55309543a9
Publikováno v:
The Journal of Infectious Diseases. 217:1637-1644
Background Current Streptococcus pneumoniae vaccines selectively target capsular polysaccharide of specific serotypes, leading to an increase in nonencapsulated S. pneumoniae (NESp). Cocolonization by encapsulated pneumococci and NESp increases the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f726bdc6304f5b2cd6c909e46a01bc
https://doi.org/10.1093/infdis/jiy058
https://doi.org/10.1093/infdis/jiy058
Here we describe the creation of three integration vectors, pPEPX, pPEPY and pPEPZ, for use with the opportunistic human pathogenStreptococcus pneumoniae. The constructed vectors, named PEP for Pneumococcal Engineering Platform, employ an IPTG-induci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1238dae1506bba16fdfdb71b04532408
https://doi.org/10.1101/594697
https://doi.org/10.1101/594697
Autor:
D. Ashley Robinson, Lance E. Keller, Justin A. Thornton, Keun-Seok Seo, Larry S. McDaniel, Bo Youn Moon, Xiao Luo
Publikováno v:
Clinical and Vaccine Immunology. 22:1146-1153
Current vaccinations are effective against encapsulated strains of Streptococcus pneumoniae , but they do not protect against nonencapsulated Streptococcus pneumoniae (NESp), which is increasing in colonization and incidence of pneumococcal disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d251d5ad29cad0a4848b0750c6daa3
https://doi.org/10.1128/cvi.00456-15
https://doi.org/10.1128/cvi.00456-15