Long-term effects of patiromer for hyperkalaemia treatment in patients with mild heart failure and diabetic nephropathy on angiotensin-converting enzymes/angiotensin receptor blockers: results from AMETHYST-DN

Autor: Lance Berman, Martha Mayo, Bertram Pitt, Mitja Lainscak, George L. Bakris, Matthew R. Weir, Rezi Zawadzki, Mason W. Freeman, David A. Bushinsky, Dahlia Garza

Publikováno v: ESC Heart Failure. 5:592-602

Aims Chronic kidney disease (CKD) in heart failure (HF) increases the risk of hyperkalaemia (HK), limiting angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin receptor blocker (ARB) use. Patiromer is a sodium-free, non-absorbed potassium b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b692f84eb2d7e0172ab604a7585d902f
https://doi.org/10.1002/ehf2.12292

Effectiveness of patiromer in the treatment of hyperkalemia in chronic kidney disease patients with hypertension on diuretics

Autor: Martha Mayo, Susan Arthur, Murray Epstein, Matthew R. Weir, Lance Berman, Dahlia Garza, David A. Bushinsky, Daniel J. Wilson

Publikováno v: Journal of Hypertension

Objective: Recurrent hyperkalemia frequently limits use of renin–angiotensin–aldosterone system inhibitors (RAASi) in chronic kidney disease (CKD) patients with hypertension, diabetes, and/or heart failure. Patiromer is a sodium-free, nonabsorbed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987b2f62e73da50d70878a48d9820a14
https://doi.org/10.1097/hjh.0000000000001278

Mechanism of Action and Pharmacology of Patiromer, a Nonabsorbed Cross-Linked Polymer That Lowers Serum Potassium Concentration in Patients With Hyperkalemia

Autor: M. Jamie T.V. Cope, Lawrence Lee, Faleh Salaymeh, Stephen D. Harrison, Lance Berman, Jerry M. Buysse, Craig Park, Wade W. Benton, Lingyun Li, Deidre Madsen

Publikováno v: Journal of Cardiovascular Pharmacology and Therapeutics

Hyperkalemia is a potentially life-threatening condition, and patients who have chronic kidney disease, who are diabetic, or who are taking renin–angiotensin–aldosterone system inhibitors are at increased risk. Therapeutic options for hyperkalemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ef43ec4defeba8f8afeace65669dd9
https://doi.org/10.1177/1074248416629549

Effect of patiromer on reducing serum potassium and preventing recurrent hyperkalaemia in patients with heart failure and chronic kidney disease onRAASinhibitors

Autor: Heidi Christ-Schmidt, David A. Bushinsky, Lance Berman, Yuri Stasiv, Bertram Pitt, Martha Mayo, Dahlia Garza, Matthew R. Weir, George L. Bakris

Publikováno v: European Journal of Heart Failure. 17:1057-1065

Aims We evaluated the effects of patiromer, a potassium (K+)-binding polymer, in a pre-specified analysis of hyperkalaemic patients with heart failure (HF) in the OPAL-HK trial. Methods and results Chronic kidney disease (CKD) patients on renin–ang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78ec90321130e7ed5f5fa65ea45b0610
https://doi.org/10.1002/ejhf.402

New approaches to hyperkalemia in patients with indications for renin angiotensin aldosterone inhibitors: Considerations for trial design and regulatory approval

Autor: Mikhail Kosiborod, Maria Angeles Alonso Garcia, Norman Stockbridge, Henrik S. Rasmussen, Javed Butler, Aliza Thompson, Bertram Pitt, Murray Epstein, Lance Berman, Alexandre Mebazaa, Faiez Zannad, George L. Bakris, Janet Wittes, Patrick Rossignol, Luis M. Ruilope, Wendy Gattis Stough

Publikováno v: International Journal of Cardiology
International Journal of Cardiology, Elsevier, 2016, 216, pp.46-51. ⟨10.1016/j.ijcard.2016.04.127⟩

International audience; Hyperkalemia is a common clinical problem, especially in patients with chronic kidney disease, diabetes mellitus, or heart failure. Treatment with renin angiotensin aldosterone system inhibitors exacerbates the risk of hyperka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac4a020faacccca71325f2fd5518d6f
https://pubmed.ncbi.nlm.nih.gov/27140336