Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Lanbo Shi"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Innate immune cells, such as macrophages, mount an immune response upon exposure to antigens and pathogens. Emerging evidence shows that macrophages exposed to an antigen can generate a “memory-like” response (a.k.a. trained immunity), w
Externí odkaz:
https://doaj.org/article/0f87e52fdedf4779bd3c811a4c598d7e
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0b95bf3abb2a43efbc5dc87882f41bb1
Autor:
Saiaditya Badeti, Qingkui Jiang, Alireza Naghizadeh, Hsiang-chi Tseng, Yuri Bushkin, Salvatore A. E. Marras, Annuurun Nisa, Sanjay Tyagi, Fei Chen, Peter Romanienko, Ghassan Yehia, Deborah Evans, Moises Lopez-Gonzalez, David Alland, Riccardo Russo, William Gause, Lanbo Shi, Dongfang Liu
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Background An animal model that can mimic the SARS-CoV-2 infection in humans is critical to understanding the rapidly evolving SARS-CoV-2 virus and for development of prophylactic and therapeutic strategies to combat emerging mutants. Studie
Externí odkaz:
https://doaj.org/article/cfa6484b283a404981d9a83beb24bf3b
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Recent work indicates that male fertility is compromised by SARS-CoV-2 infection. Direct effects derive from the presence of viral entry receptors (ACE2 and/or CD147) on the surface of testicular cells, such as spermatocytes, Sertoli cells,
Externí odkaz:
https://doaj.org/article/5bbfab8b73da4d3486e12e747a20485b
Autor:
Qingkui Jiang, Yunping Qiu, Irwin J. Kurland, Karl Drlica, Selvakumar Subbian, Sanjay Tyagi, Lanbo Shi
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT In response to Mycobacterium tuberculosis infection, macrophages mount proinflammatory and antimicrobial responses similar to those observed in M1 macrophages activated by lipopolysaccharide (LPS) and interferon gamma (IFN-γ). A metabolic r
Externí odkaz:
https://doaj.org/article/23475556c712462c94db85b48b4cf5bf
Autor:
Qingkui Jiang, Lanbo Shi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Macrophage polarization to the M1-like phenotype, which is critical for the pro-inflammatory and antimicrobial responses of macrophages against intracellular pathogens, is associated with metabolic reprogramming to the Warburg effect and a high outpu
Externí odkaz:
https://doaj.org/article/3315410c0de14fd199faedcdd234c208
Autor:
Minh Tuyet Ma, Saiaditya Badeti, Chih-Hsiung Chen, James Kim, Alok Choudhary, Bill Honnen, Charles Reichman, David Calianese, Abraham Pinter, Qingkui Jiang, Lanbo Shi, Renping Zhou, Huanbin Xu, Qingsheng Li, William Gause, Dongfang Liu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is highly contagious and presents a significant public health issue. Current therapies used to treat coronavirus disease 2019 (COVID-19) include monoclonal antibody cocktail, convalescent p
Externí odkaz:
https://doaj.org/article/bed4d20d522a4d9d80692c410188687e
Autor:
Qingkui Jiang, Constanze C. Maresch, Sebastian Friedrich Petry, Agnieszka Paradowska-Dogan, Sudhanshu Bhushan, Yongsheng Chang, Christine Wrenzycki, Hans-Christian Schuppe, Petr Houska, Michaela F. Hartmann, Stefan A. Wudy, Lanbo Shi, Thomas Linn
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Metabolic syndrome (MetS), which is associated with chronic inflammation, predisposes males to hypogonadism and subfertility. The underlying mechanism of these pathologies remains poorly understood. Homozygous leptin-resistant obese db/db mice are ch
Externí odkaz:
https://doaj.org/article/ddf223fd27204181bfff8c75dbf25043
Autor:
Ranjeet Kumar, Pooja Singh, Afsal Kolloli, Lanbo Shi, Yuri Bushkin, Sanjay Tyagi, Selvakumar Subbian
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) remains as a leading killer among infectious diseases worldwide. The nature of the host immune response dictates whether the initial Mtb infection is cleared or progresses toward active di
Externí odkaz:
https://doaj.org/article/af3f8e9a3b5141ccb6ac38736e3e619c
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Macrophages are the primary targets of Mycobacterium tuberculosis infection; the early events of macrophage interaction with M. tuberculosis define subsequent progression and outcome of infection. M. tuberculosis can alter the innate immunit
Externí odkaz:
https://doaj.org/article/7656e054cd27456dbf81e74fb6058250