Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lana M. Pollock"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Microglia are resident immune cells in the central nervous system, including the retina that surveil the environment for damage and infection. Following retinal damage, microglia undergo morphological changes, migrate to the site of damage,
Externí odkaz:
https://doaj.org/article/71d953ff464245aaaf5b086720c5e197
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0225351 (2020)
Endothelial cilia are found in a variety of tissues including the cranial vasculature of zebrafish embryos. Recently, endothelial cells in the developing mouse retina were reported to also possess primary cilia that are potentially involved in vascul
Externí odkaz:
https://doaj.org/article/8b32c075e90648abb941dc628f5b13e8
ADAMTS1, MPDZ, MVD, and SEZ6:candidate genes for autosomal recessive nonsyndromic hearing impairment
Autor:
Saima Riazuddin, Sakina Rehman, Liz M Nouel-Saied, Muhammad Ansar, Anushree Acharya, Shaoyuan Zhu, Lana M. Pollock, Ghazanfar Ali, Regie Lyn P. Santos-Cortez, Wasim Ahmad, Thashi Bharadwaj, Jenna L. Everard, Asmat Ullah, Khurram Liaqat, Michael J. Bamshad, Suzanne M. Leal, Isabelle Schrauwen, Brian M. McDermott, Raja Hussain Ali, Abdul Nasir, Abdul Wali, Arnaud P. J. Giese, Deborah A. Nickerson, Zubair M. Ahmed
Publikováno v:
Bharadwaj, T, Schrauwen, I, Rehman, S, Liaqat, K, Acharya, A, Giese, A P J, Nouel-Saied, L M, Nasir, A, Everard, J L, Pollock, L M, Zhu, S, Bamshad, M J, Nickerson, D A, Ali, R H, Ullah, A, Wali, A, Ali, G, Santos-Cortez, R L P, Ahmed, Z M, McDermott, B M, Ansar, M, Riazuddin, S, Ahmad, W & Leal, S M 2022, ' ADAMTS1, MPDZ, MVD, and SEZ6 : candidate genes for autosomal recessive nonsyndromic hearing impairment ', European Journal of Human Genetics, vol. 30, pp. 22-33 . https://doi.org/10.1038/s41431-021-00913-x
Hearing impairment (HI) is a common disorder of sensorineural function with a highly heterogeneous genetic background. Although substantial progress has been made in the understanding of the genetic etiology of hereditary HI, many genes implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b3797ece0eb90be2e775eda90491d2
https://curis.ku.dk/ws/files/289458884/s41431_021_00913_x.pdf
https://curis.ku.dk/ws/files/289458884/s41431_021_00913_x.pdf
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158349 (2016)
The organ of Corti has evolved a panoply of cells with extraordinary morphological specializations to harness, direct, and transduce mechanical energy into electrical signals. Among the cells with prominent apical specializations are hair cells and n
Externí odkaz:
https://doaj.org/article/fea6ed4bc76e4ec492ad78ef613f0dc0
Autor:
Jessica C Price, Lana M Pollock, Meghan L Rudd, Sarah K Fogoros, Hassan Mohamed, Christin L Hanigan, Matthieu Le Gallo, NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program, Suiyuan Zhang, Pedro Cruz, Praveen F Cherukuri, Nancy F Hansen, Kirk J McManus, Andrew K Godwin, Dennis C Sgroi, James C Mullikin, Maria J Merino, Philip Hieter, Daphne W Bell
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e63313 (2014)
Most endometrial cancers can be classified histologically as endometrioid, serous, or clear cell. Non-endometrioid endometrial cancers (NEECs; serous and clear cell) are the most clinically aggressive of the three major histotypes and are characteriz
Externí odkaz:
https://doaj.org/article/3e6912cd2b044f93a13ec39d39f4d8c9
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0225351 (2020)
PLoS ONE, Vol 15, Iss 7, p e0225351 (2020)
Endothelial cilia are found in a variety of tissues including the cranial vasculature of zebrafish embryos. Recently, endothelial cells in the developing mouse retina were reported to also possess primary cilia that are potentially involved in vascul
Publikováno v:
The FASEB Journal. 32:5674-5684
The predominant function of the blood-retinal barrier (BRB) is to maintain retinal homeostasis by regulating the influx and efflux between the blood and retina. Breakdown of the BRB occurs in a number of ocular diseases that result in vision loss. Un
Autor:
Daphne W Bell, Nilabja Sikdar, Kyoo-Young Lee, Jessica C Price, Raghunath Chatterjee, Hee-Dong Park, Jennifer Fox, Masamichi Ishiai, Meghan L Rudd, Lana M Pollock, Sarah K Fogoros, Hassan Mohamed, Christin L Hanigan, NISC Comparative Sequencing Program, Suiyuan Zhang, Pedro Cruz, Gabriel Renaud, Nancy F Hansen, Praveen F Cherukuri, Bhavesh Borate, Kirk J McManus, Jan Stoepel, Payal Sipahimalani, Andrew K Godwin, Dennis C Sgroi, Maria J Merino, Gene Elliot, Abdel Elkahloun, Charles Vinson, Minoru Takata, James C Mullikin, Tyra G Wolfsberg, Philip Hieter, Dae-Sik Lim, Kyungjae Myung
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002245 (2011)
ATAD5, the human ortholog of yeast Elg1, plays a role in PCNA deubiquitination. Since PCNA modification is important to regulate DNA damage bypass, ATAD5 may be important for suppression of genomic instability in mammals in vivo. To test this hypothe
Externí odkaz:
https://doaj.org/article/f77e2c0ad98744ec84cad927ff742253
Autor:
Shih-Wei Chou, Philsang Hwang, Gustavo Gomez, Carol A Fernando, Megan C West, Lana M Pollock, Jennifer Lin-Jones, Beth Burnside, Brian M McDermott
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e14807 (2011)
Stereocilia are actin-filled protrusions that permit mechanotransduction in the internal ear. To identify proteins that organize the cytoskeleton of stereocilia, we scrutinized the hair-cell transcriptome of zebrafish. One promising candidate encodes
Externí odkaz:
https://doaj.org/article/499b9417dd124ad383fe836cee125988
Autor:
Brian M. McDermott, Lana M. Pollock
Publikováno v:
Birth Defects Research Part C: Embryo Today: Reviews. 105:126-139
The mechanosensitive hair cells of the inner ear are crucial to hearing and vestibular function. Each hair cell detects the mechanical stimuli associated with sound or head movement with a hair bundle at the apical surface of the cell, consisting of