Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Lana M. Chahine"'
Autor:
Tien Dam, Gennaro Pagano, Michael C. Brumm, Caroline Gochanour, Kathleen L. Poston, Daniel Weintraub, Lana M. Chahine, Christopher Coffey, Caroline M. Tanner, Catherine M. Kopil, Yuge Xiao, Sohini Chowdhury, Luis Concha-Marambio, Peter DiBiaso, Tatiana Foroud, Mark Frasier, Danna Jennings, Karl Kieburtz, Kalpana Merchant, Brit Mollenhauer, Thomas J. Montine, Kelly Nudelman, John Seibyl, Todd Sherer, Andrew Singleton, Diane Stephenson, Matthew Stern, Claudio Soto, Eduardo Tolosa, Andrew Siderowf, Billy Dunn, Tanya Simuni, Kenneth Marek, the Parkinson’s Progression Markers Initiative
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The Neuronal alpha-Synuclein Disease (NSD) biological definition and Integrated Staging System (NSD-ISS) provide a research framework to identify individuals with Lewy body pathology and stage them based on underlying biology and increasing
Externí odkaz:
https://doaj.org/article/bcf123a33df949f9999736ef3c3dd94e
Autor:
Lana M. Chahine, Thomas G. Beach, Charles H. Adler, Monica Hepker, Anumantha Kanthasamy, Scott Appel, Sandra Pritzkow, Michelle Pinho, Sherri Mosovsky, Geidy E. Serrano, Christopher Coffey, Michael C. Brumm, Luis M. A. Oliveira, Jamie Eberling, Brit Mollenhauer, For the Systemic Synuclein Sampling Study
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 696-705 (2023)
Abstract Objectives Detection of α‐synuclein aggregates by seed amplification is a promising Parkinson disease biomarker assay. Understanding intraindividual relationships of α‐synuclein measures could inform optimal biomarker development. The
Externí odkaz:
https://doaj.org/article/55394691e8324b6891e055c38a0be7d4
Autor:
Tanya Simuni, Kalpana Merchant, Michael C. Brumm, Hyunkeun Cho, Chelsea Caspell-Garcia, Christopher S. Coffey, Lana M. Chahine, Roy N. Alcalay, Kelly Nudelman, Tatiana Foroud, Brit Mollenhauer, Andrew Siderowf, Caroline Tanner, Hirotaka Iwaki, Todd Sherer, Kenneth Marek, Parkinson’s Progression Marker Initiative Authors
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract We examined 2-year longitudinal change in clinical features and biomarkers in LRRK2 non-manifesting carriers (NMCs) versus healthy controls (HCs) enrolled in the Parkinson’s Progression Markers Initiative (PPMI). We analyzed 2-year longitu
Externí odkaz:
https://doaj.org/article/e1d372d98f1946328be0eae48783c3df
Autor:
Maxim Signaevsky, Bahram Marami, Marcel Prastawa, Nabil Tabish, Megan A. Iida, Xiang Fu Zhang, Mary Sawyer, Israel Duran, Daniel G. Koenigsberg, Clare H. Bryce, Lana M. Chahine, Brit Mollenhauer, Sherri Mosovsky, Lindsey Riley, Kuldip D. Dave, Jamie Eberling, Chris S. Coffey, Charles H. Adler, Geidy E. Serrano, Charles L. White, John Koll, Gerardo Fernandez, Jack Zeineh, Carlos Cordon-Cardo, Thomas G. Beach, John F. Crary
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract The diagnosis of Parkinson’s disease (PD) is challenging at all stages due to variable symptomatology, comorbidities, and mimicking conditions. Postmortem assessment remains the gold standard for a definitive diagnosis. While it is well re
Externí odkaz:
https://doaj.org/article/0a6596c1690b41888b8e6df98e40c352
Autor:
Lana M. Chahine, Lakshmi Arbatti, Abhishek Hosamath, Amy Amara, Karen E. Anderson, Jennifer Purks, Shirley Eberly, Daniel Kinel, Sneha Mantri, Soania Mathur, David Oakes, David G. Standaert, Daniel Weintraub, Ira Shoulson, Connie Marras
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100229- (2023)
Introduction: Internal tremor (IT) occurs in > 30 % of people with Parkinson’s Disease (PwPD), but remains largely uninvestigated. Our objective was to describe demographic characteristics and associated symptoms in PwPD who reported IT. Methods: T
Externí odkaz:
https://doaj.org/article/0d5f2748e94a4aff839c358b9ae67ab3
Autor:
Sneha Mantri, Madeline Lepore, Briana Edison, Margaret Daeschler, Catherine M. Kopil, Connie Marras, Lana M. Chahine
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 8, Iss 3, Pp 232-238 (2021)
Purpose: Wearing off of Parkinson’s disease medication is common, but triggers and coping strategies for this transient phenomenon are poorly understood. We aimed to assess the lived experience of OFF periods for people with Parkinson’s disease.
Externí odkaz:
https://doaj.org/article/0f69f74f97aa469c83d2d02df3dd5fc8
Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease
Autor:
Daniel Weintraub, Chelsea Caspell‐Garcia, Tanya Simuni, Hyunkeun R. Cho, Christopher S. Coffey, Dag Aarsland, Roy N. Alcalay, Matthew J. Barrett, Lana M. Chahine, Jamie Eberling, Alberto J. Espay, Jamie Hamilton, Keith A. Hawkins, James Leverenz, Irene Litvan, Irene Richard, Liana S. Rosenthal, Andrew Siderowf, Michele York, Parkinson’s Progression Markers Initiative
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 4, Pp 449-461 (2020)
Abstract Objective To determine the evolution of numerous neuropsychiatric symptoms and cognitive abilities in Parkinson disease from disease onset. Methods Prospectively collected, longitudinal (untreated, disease onset to year 5), observational dat
Externí odkaz:
https://doaj.org/article/1733fdc8d0954e2d9d18b60b48a839a0
Autor:
Cynthia Felix, Lana M. Chahine, James Hengenius, Honglei Chen, Andrea L. Rosso, Xiaonan Zhu, Zichun Cao, Caterina Rosano
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Objectives: To compare gray matter microstructural characteristics of higher-order olfactory regions among older adults with and without hyposmia.Methods: Data from the Brief Smell Identification Test (BSIT) were obtained in 1998–99 for 265 dementi
Externí odkaz:
https://doaj.org/article/b1200d0aa03848059577aeb1418f16d5
Autor:
Sneha Mantri, Briana Edison, Lamees Alzyoud, Steven M. Albert, Margaret Daeschler, Catherine Kopil, Connie Marras, Lana M. Chahine
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Introduction: Care partners (CPs) of individuals with Parkinson disease psychosis (PDP) experience increased strain and rely on informal support networks. The objective of this study was to characterize CP responsibilities, sources of support, and pe
Externí odkaz:
https://doaj.org/article/331990a514e341eda8b6438f491924cf
Autor:
Kristine A. Wilckens, Lana M. Chahine
Publikováno v:
Neurobiology of Disease, Vol 145, Iss , Pp 105075- (2020)
Externí odkaz:
https://doaj.org/article/ea42977bbd5c46a78933c05def61b7f7