In vitro study of the role of thrombin in platelet rich plasma (PRP) preparation: utility for gel formation and impact in growth factors release

Autor: Huber SC, Cunha JL, Montalvão SAL, da Silva LQ, Paffaro AU, da Silva FAR, Rodrigues BL, Lana JFSD, Annichino-Bizzacchi JM

Publikováno v: Journal of Stem Cells and Regenerative Medicine, Vol 12, Iss 1, Pp 2-9 (2016)

Introduction: The use of PRP has been studied for different fields, with promising results in regenerative medicine. Until now, there is no study in the literature evaluating thrombin levels in serum, used as autologous thrombin preparation. Therefor

Externí odkaz: https://doaj.org/article/947f0b4b779b43bcad9e3ea78497f6c1

SDIMMMER: A Proposed Clinical Approach to Optimize Cellular Physiology in Regenerative Medicine.

Autor: Lana JV; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil., Lana JF; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil.; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Clinical Research, Anna Vitória Lana Institute (IAVL), Indaiatuba 13334-170, SP, Brazil.; Medical School, Jaguariúna University Center (UniFAJ), Jaguariúna 13820-000, SP, Brazil., Melo G; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil., Azzini GOM; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Santos GS; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Mosaner T; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Jorge DMF; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., da Fonseca LF; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Kruel A; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Costa FR; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Department of Orthopedics, FC Sports Traumatology, Salvador 40296-210, BA, Brazil., Jeyaraman M; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Department of Orthopedics, ACS Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai 600077, Tamil Nadu, India., de Macedo AP; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Santos N; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Pires L; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Tambeli CH; Institute of Biology, State University of Campinas (UNICAMP), Campinas 13083-852, SP, Brazil.

Publikováno v: Life (Basel, Switzerland) [Life (Basel)] 2024 Oct 11; Vol. 14 (10). Date of Electronic Publication: 2024 Oct 11.

Evolution and Innovations in Bone Marrow Cellular Therapy for Musculoskeletal Disorders: Tracing the Historical Trajectory and Contemporary Advances.

Autor: Lana JF; Department of Orthopaedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil.; Clinical Research, Anna Vitória Lana Institute (IAVL), Indaiatuba 13334-170, SP, Brazil.; Medical School, Jaguariúna University Center (UniFAJ), Jaguariúna 13820-000, SP, Brazil., de Brito GC; Department of Orthopaedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil., Kruel A; Department of Orthopaedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil., Brito B; Department of Orthopaedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil., Santos GS; Department of Orthopaedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil., Caliari C; Cell Therapy, In Situ Terapia Celular, Ribeirão Preto 14056-680, SP, Brazil., Salamanna F; Surgical Sciences and Technologies, IRCCS Instituto Ortopedizo Rizzoli, 40136 Bologna, Italy., Sartori M; Surgical Sciences and Technologies, IRCCS Instituto Ortopedizo Rizzoli, 40136 Bologna, Italy., Barbanti Brodano G; Spine Surgery Unit, IRCCS Instituto Ortopedizo Rizzoli, 40136 Bologna, Italy., Costa FR; Department of Orthopaedics, FC Sports Traumatology, Salvador 40296-210, BA, Brazil., Jeyaraman M; Department of Orthopaedics, ACS Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai 600077, Tamil Nadu, India.; Orthopaedic Research Group, Coimbatore 641045, Tamil Nadu, India.; Clinical Research Scientist, Virginia Tech India, Chennai 600095, Tamil Nadu, India., Dallo I; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil.; Orthopedics, SportMe Medical Center, 41013 Seville, Spain., Bernaldez P; Orthopedics, SportMe Medical Center, 41013 Seville, Spain., Purita J; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil., Andrade MAP; Department of the Locomotor Apparatus, Federal University of Minas Gerais, Belo Horizonte 31270-901, MG, Brazil., Everts PA; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil.; Gulf Coast Biologics, Fort Myers, FL 33916, USA.

Publikováno v: Bioengineering (Basel, Switzerland) [Bioengineering (Basel)] 2024 Sep 28; Vol. 11 (10). Date of Electronic Publication: 2024 Sep 28.

ViSCNOVAS: A Novel Classification System for Hyaluronic Acid-Based Gels in Orthobiologic Products and Regenerative Medicine.

Autor: Costa FR; Department of Orthopedics, FC Sports Traumatology, Salvador 40296-210, BA, Brazil., Pires L; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Martins RA; Medical School, Tiradentes University Center, Maceió 57038-000, AL, Brazil., Costa BR; Medical School, Zarns College, Salvador 41720-200, BA, Brazil., Santos GS; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil., Lana JF; Department of Orthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, SP, Brazil.; Regenerative Medicine, Orthoregen International Course, Indaiatuba 13334-170, SP, Brazil.; Clinical Research, Anna Vitória Lana Institute (IAVL), Indaiatuba 13334-170, SP, Brazil.; Medical School, Max Planck University Center (UniMAX), Indaiatuba 13343-060, SP, Brazil.; Medical School, Jaguariúna University Center (UniFAJ), Jaguariúna 13911-094, SP, Brazil.

Publikováno v: Gels (Basel, Switzerland) [Gels] 2024 Aug 02; Vol. 10 (8). Date of Electronic Publication: 2024 Aug 02.

Profound Properties of Protein-Rich, Platelet-Rich Plasma Matrices as Novel, Multi-Purpose Biological Platforms in Tissue Repair, Regeneration, and Wound Healing.

Autor: Everts PA; Gulf Coast Biologics, A Non-Profit Organization, Fort Myers, FL 33916, USA.; OrthoRegen Group, Max-Planck University, Indaiatuba 13334-170, SP, Brazil., Lana JF; OrthoRegen Group, Max-Planck University, Indaiatuba 13334-170, SP, Brazil., Alexander RW; Regenevita Biocellular Aesthetic & Reconstructive Surgery, Cranio-Maxillofacial Surgery, Regenerative and Wound Healing, Hamilton, MT 59840, USA.; Department of Surgery & Maxillofacial Surgery, School of Medicine & Dentistry, University of Washington, Seattle, WA 98195, USA., Dallo I; Unit of Biological Therapies and MSK Interventionism, Department of Orthopaedic Surgery and Sports Medicine, Sport Me Medical Center, 41013 Seville, Spain., Kon E; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, 20072 Milan, Italy.; IRCCS Humanitas Research Hospital, Rozzano, 20089 Milan, Italy., Ambach MA; BioEvolve, San Diego Orthobiologics and Sports Center, San Diego, CA 92024, USA., van Zundert A; Department of Anaesthesia and Perioperative Medicine, Royal Brisbane and Women's Hospital, Brisbane and The University of Queensland, Brisbane 4072, Australia., Podesta L; Bluetail Medical Group & Podesta Orthopedic Sports Medicine, Naples, FL 34109, USA.; Physical Medicine & Rehabilitation Orlando College of Osteopathic Medicine, Orlando, FL 32806, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 19; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 19.