Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lana Harley"'
Autor:
Sezen Meydan, Géssica C. Barros, Vanessa Simões, Lana Harley, Blanche K. Cizubu, Nicholas R. Guydosh, Gustavo M. Silva
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113359- (2023)
Summary: Oxidative stress causes K63-linked ubiquitination of ribosomes by the E2 ubiquitin conjugase Rad6. How Rad6-mediated ubiquitination of ribosomes affects translation, however, is unclear. We therefore perform Ribo-seq and Disome-seq in Saccha
Externí odkaz:
https://doaj.org/article/60c50936146e4876a458eb95a3f76dfc
Autor:
Sezen Meydan, Géssica C. Barros, Vanessa Simões, Lana Harley, Blanche K. Cizubu, Nicholas R. Guydosh, Gustavo M. Silva
SUMMARYOxidative stress causes K63-linked ubiquitination of ribosomes by the E2 ubiquitin conjugase, Rad6. How Rad6-mediated ubiquitination of ribosomes affects global translation, however, is unclear. We therefore performed Ribo-seq and Disome-seq i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87c48565ccf870f707829c0bf72e1fcc
https://doi.org/10.1101/2022.09.27.509727
https://doi.org/10.1101/2022.09.27.509727
Autor:
Vanessa Simões, Blanche K. Cizubu, Lana Harley, Ye Zhou, Joshua Pajak, Nathan A. Snyder, Jonathan Bouvette, Mario J. Borgnia, Gaurav Arya, Alberto Bartesaghi, Gustavo M. Silva
Publikováno v:
Cell reports. 39(8)
Protein ubiquitination is an essential process that rapidly regulates protein synthesis, function, and fate in dynamic environments. Within its non-proteolytic functions, we showed that K63-linked polyubiquitinated conjugates heavily accumulate in ye