Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Lana Fani"'
Autor:
Lana Fani, Marios K. Georgakis, M. Arfan Ikram, M. Kamran Ikram, Rainer Malik, Martin Dichgans
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The aim of this study was to explore the association between genetically predicted circulating levels of immunity and inflammation, and the risk of Alzheimer’s disease (AD) and hippocampal volume, by conducting a two-sample Mendelian Rando
Externí odkaz:
https://doaj.org/article/ca4e4ac5705f4dd18aa7561a0e321a60
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Herpes simplex virus 1 (HSV1) is a neuroinvasive virus capable of entering the brain which makes it a candidate pathogen for increasing risk of dementia. Previous studies are inconsistent in their findings regarding the link between HSV1 and
Externí odkaz:
https://doaj.org/article/23764de55bc6447aa2f82d32e924c624
Publikováno v:
PLoS Medicine, Vol 19, Iss 3 (2022)
Background Apart from blood pressure level itself, variation in blood pressure has been implicated in the development of stroke in subgroups at high cardiovascular risk. We determined the association between visit-to-visit blood pressure variability
Externí odkaz:
https://doaj.org/article/1538621502804e528210e51a5a3af165
Autor:
Lana Fani, Alis Heshmatollah, M Kamran Ikram, Maryam Kavousi, Kan Wang, Fariba Ahmadizar, Elif Aribas
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/cffb552fe6dc49b89475af46af396a25
Autor:
Kimberly D. van der Willik, Lana Fani, Dimitris Rizopoulos, Silvan Licher, Jesse Fest, Sanne B. Schagen, M. Kamran Ikram, M. Arfan Ikram
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background Immunity has been suggested to be important in the pathogenesis of dementia. However, the contribution of innate versus adaptive immunity in the development of dementia is not clear. In this study, we aimed to investigate (1) the
Externí odkaz:
https://doaj.org/article/59fc9b3c7e3e49378ce6f746dd085bb0
Autor:
Vikram Venkatraghavan, Stefan Klein, Lana Fani, Leontine S. Ham, Henri Vrooman, M. Kamran Ikram, Wiro J. Niessen, Esther E. Bron
Publikováno v:
NeuroImage, Vol 227, Iss , Pp 117646- (2021)
Alzheimer’s disease (AD) is the most common form of dementia and is phenotypically heterogeneous. APOE is a triallelic gene which correlates with phenotypic heterogeneity in AD. In this work, we determined the effect of APOE alleles on the disease
Externí odkaz:
https://doaj.org/article/90da3ae9bbf144d9bc5d78754d50ed07
Autor:
Lana Fani, Kimberly D van der Willik, Daniel Bos, Maarten J G Leening, Peter J Koudstaal, Dimitris Rizopoulos, Rikje Ruiter, Bruno H C Stricker, Maryam Kavousi, M Arfan Ikram, M Kamran Ikram
Publikováno v:
PLoS Medicine, Vol 17, Iss 5, p e1003115 (2020)
BackgroundAtherosclerotic cardiovascular disease (ASCVD) is driven by multifaceted contributions of the immune system. However, the dysregulation of immune cells that leads to ASCVD is poorly understood. We determined the association of components of
Externí odkaz:
https://doaj.org/article/1016d42f04194cfdb2203d26b8685ad2
Autor:
Lana Fani, Daniel Bos, Unal Mutlu, Marileen L.P. Portegies, Hazel I. Zonneveld, Peter J. Koudstaal, Meike W. Vernooij, M. Arfan Ikram, M. Kamran Ikram
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 7 (2019)
Background The role of subtle disturbances of brain perfusion in the risk of transient ischemic attack (TIA) or ischemic stroke remains unknown. We examined the association between global brain perfusion and risk of TIA and ischemic stroke in the gen
Externí odkaz:
https://doaj.org/article/71c72fa9d984471ea630dc0d957bc5ed
Autor:
Silvan Licher, Alis Heshmatollah, Kimberly D van der Willik, Bruno H Ch Stricker, Rikje Ruiter, Emmely W de Roos, Lies Lahousse, Peter J Koudstaal, Albert Hofman, Lana Fani, Guy G O Brusselle, Daniel Bos, Banafsheh Arshi, Maryam Kavousi, Maarten J G Leening, M Kamran Ikram, M Arfan Ikram
Publikováno v:
PLoS Medicine, Vol 16, Iss 2, p e1002741 (2019)
BACKGROUND:Non-communicable diseases (NCDs) are leading causes of premature disability and death worldwide. However, the lifetime risk of developing any NCD is unknown, as are the effects of shared common risk factors on this risk. METHODS AND FINDIN
Externí odkaz:
https://doaj.org/article/aca00a14f3134519ba286e4ac73956de
Autor:
Alis Heshmatollah, Lana Fani, Peter J. Koudstaal, Mohsen Ghanbari, M. Arfan Ikram, M. Kamran Ikram
Publikováno v:
Neurology, 98(17), E1729-E1737. Lippincott Williams & Wilkins
Background and ObjectivesTo unravel whether Alzheimer disease–related pathology or neurodegeneration plays a role in stroke etiology, we determined the effect of plasma levels β-amyloid (Aβ), total-tau, and neurofilament light chain (NfL) on risk