Zobrazeno 1 - 4
of 4
pro vyhledávání: '"LanHsin Liu"'
Autor:
Rintaro Tsukahara, LanHsin Liu, Henry J. Kaplan, Kazuhiko Umazume, Kevin McDonald, Juan P. Fernandez de Castro, Shigeo Tamiya
Publikováno v:
The American journal of pathology. 184(5)
Proliferative vitreoretinopathy is caused by the contraction of fibrotic membranes on the epiretinal surface of the neurosensory retina, resulting in a traction retinal detachment and loss of visual acuity. Retinal pigment epithelial (RPE) cells play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693fcb8afde936e89c86d6ab96e7add7
https://pubmed.ncbi.nlm.nih.gov/24656918
https://pubmed.ncbi.nlm.nih.gov/24656918
Publikováno v:
Investigative ophthalmologyvisual science. 53(8)
Purpose To develop a large animal model of proliferative vitreoretinopathy (PVR) in the swine to eventually study disease pathophysiology, as well as novel therapies. Methods PVR was induced in domestic swine by creation of a posterior vitreous detac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae75537799f8f240d5e7e6e2d6f94bf
https://pubmed.ncbi.nlm.nih.gov/22729438
https://pubmed.ncbi.nlm.nih.gov/22729438
Publikováno v:
Investigative ophthalmologyvisual science. 51(5)
Purpose Molecular mechanisms that initiate epithelial-mesenchymal transition (EMT) involved in ocular fibrotic complications remain elusive. Studies were conducted to examine the role of cell-cell contact in regulating EMT and proliferation of retina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ac5655b65ccaef24eb9162a250a233
https://pubmed.ncbi.nlm.nih.gov/20042656
https://pubmed.ncbi.nlm.nih.gov/20042656
Autor:
Shigeo Tamiya, Henry J. Kaplan, LanHsin Liu, Kevin McDonald, Juan P. Fernandez de Castro, Kazuhiko Umazume, Patrick A. Scott
Publikováno v:
Investigative Opthalmology & Visual Science. 54:1150
PURPOSE. We tested the efficacy of dasatinib, a Food and Drug Administration (FDA)-approved tyrosine kinase inhibitor, to prevent proliferative vitreoretinopathy (PVR). METHODS. The effect of dasatinib on RPE sheet growth was determined by measuring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c826add85fbab21f9996545dcda2f33e
https://doi.org/10.1167/iovs.12-10418
https://doi.org/10.1167/iovs.12-10418