Výsledky vyhledávání - "Lan-Ying Gou"

Akademický článek

Blockade of Hedgehog Signaling Synergistically Increases Sensitivity to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Cell Lines.

Autor: Xiao-Yan Bai, Xu-Chao Zhang, Su-Qing Yang, She-Juan An, Zhi-Hong Chen, Jian Su, Zhi Xie, Lan-Ying Gou, Yi-Long Wu

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0149370 (2016)

Aberrant activation of the hedgehog (Hh) signaling pathway has been implicated in the epithelial-to-mesenchymal transition (EMT) and cancer stem-like cell (CSC) maintenance; both processes can result in tumor progression and treatment resistance in s

Externí odkaz: https://doaj.org/article/6bd7ab1b9fac4b9b9af988acec6a93d0

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Stromal PD-L1–Positive Regulatory T cells and PD-1–Positive CD8-Positive T cells Define the Response of Different Subsets of Non–Small Cell Lung Cancer to PD-1/PD-L1 Blockade Immunotherapy

Autor: Zhong-Yi Dong, Xu-Chao Zhang, Wen-Jun Wang, Yi-Long Wu, Ri-Qiang Liao, Si-Pei Wu, Hui-Wen Sun, Wei-Bang Guo, Lan-Ying Gou, Wen-Zhao Zhong, Jin-Ji Yang, Zhi Xie, Hai-Yan Tu, Shu-Mei Huang, Qi Zhang, Li-Xu Yan, Jian Su

Publikováno v: Journal of Thoracic Oncology. 13:521-532

Introduction Inhibition of programmed cell death-1 (PD-1) and its ligand programmed death ligand 1 (PD-L1) by using an immune checkpoint inhibitor has emerged as a promising immunotherapy for NSCLC. The correlation of PD-L1 expression in tumor cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f82cde583c7f1e540e1e6734ed07e67
https://doi.org/10.1016/j.jtho.2017.11.132

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Acquired MET Y1248H and D1246N Mutations Mediate Resistance to MET Inhibitors in Non–Small Cell Lung Cancer

Publikováno v: Clinical Cancer Research. 23:4929-4937

Purpose: MET amplification, responsible for 20% of acquired resistance to EGFR tyrosine kinase inhibitor (TKI) in patients with advanced non–small cell lung cancer (NSCLC), presents an attractive target. Numerous studies have conferred susceptibili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::775a8243a6dba71fc5cd29e5fc3f260f
https://doi.org/10.1158/1078-0432.ccr-16-3273

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The Unique Characteristics of MET Exon 14 Mutation in Chinese Patients with NSCLC

Autor: Si-Yang Liu, Qing Zhou, Xu-Chao Zhang, Hong-Fei Gao, Lan-Ying Gou, Yi-Long Wu, Zhong-Yi Dong, Wen-Zhao Zhong, Yang Shao, A. Li, Jian Su, Jin-Ji Yang, Na-Na Lou

Publikováno v: Journal of Thoracic Oncology. 11:1503-1510

Predictive biomarkers of mesenchymal-to-epithelial transition factor (MET)-targeted therapy remain elusive. Since the discovery of the MNNG HOS Transforming gene (MET) exon 14 mutation, it has been found to have the best potential to become one preci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a09d156c993aa100e774ff667b14193
https://doi.org/10.1016/j.jtho.2016.05.016

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The coexistence of MET over-expression and an EGFR T790M mutation is related to acquired resistance to EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer

Autor: Xu-Chao Zhang, Jian Su, Zhi Xie, Hong-Hong Yan, Yi-Long Wu, Hong-Fei Gao, Chong-Rui Xu, Zhong-Yi Dong, Jin-Ji Yang, A. Li, Wen-Zhao Zhong, Si-Yang Liu, Qing Zhou, Lan-Ying Gou, Na-Na Lou

Publikováno v: Oncotarget

// Lan-Ying Gou 1, 2, * , An-Na Li 2, * , Jin-Ji Yang 2, * , Xu-Chao Zhang 2 , Jian Su 2 , Hong-Hong Yan 2 , Zhi Xie 2 , Na-Na Lou 2 , Si-Yang Liu 2 , Zhong-Yi Dong 2 , Hong-Fei Gao 2 , Qing Zhou 2 , Wen-Zhao Zhong 2 , Chong-Rui Xu 2 , Yi-Long Wu 2 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f1f20aa8ec470b1ee0b6902febe090
https://doi.org/10.18632/oncotarget.9697

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