Výsledky vyhledávání - "Lan T. M. Dao"

Akademický článek

Epromoters function as a hub to recruit key transcription factors required for the inflammatory response

Autor: David Santiago-Algarra, Charbel Souaid, Himanshu Singh, Lan T. M. Dao, Saadat Hussain, Alejandra Medina-Rivera, Lucia Ramirez-Navarro, Jaime A. Castro-Mondragon, Nori Sadouni, Guillaume Charbonnier, Salvatore Spicuglia

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Some promoters, termed Epromoters, can display enhancer activity and regulate distal genes in their endogenous context. Here the authors report the broad involvement of Epromoters in the coordinated activation of interferon (IFN) response. They show

Externí odkaz: https://doaj.org/article/2a838a6dac1c4a42aac0c04facbcf0f8

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Akademický článek

Editorial: Computational and Experimental Approaches in Exploring the Role of Genetics and Genomics in Multifactorial Diseases

Autor: Duc-Hau Le, Quang-Huy Nguyen, Lan T. M. Dao

Publikováno v: Frontiers in Genetics, Vol 13 (2022)

Externí odkaz: https://doaj.org/article/0ee440821ed149afa023b3b368ec97cc

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Akademický článek

Integration of high-throughput reporter assays identify a critical enhancer of the Ikzf1 gene.

Autor: Jaafar Alomairi, Anne M Molitor, Nori Sadouni, Saadat Hussain, Magali Torres, Wiam Saadi, Lan T M Dao, Guillaume Charbonnier, David Santiago-Algarra, Jean Christophe Andrau, Denis Puthier, Tom Sexton, Salvatore Spicuglia

Publikováno v: PLoS ONE, Vol 15, Iss 5, p e0233191 (2020)

The Ikzf1 locus encodes the lymphoid specific transcription factor Ikaros, which plays an essential role in both T and B cell differentiation, while deregulation or mutation of IKZF1/Ikzf1 is involved in leukemia. Tissue-specific and cell identity ge

Externí odkaz: https://doaj.org/article/c6babbb5c5134b56b0768caedee2e919

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Short tandem repeats are important contributors to silencer elements in T cells

Autor: Saadat Hussain, Nori Sadouni, Dominic van Essen, Lan T M Dao, Quentin Ferré, Guillaume Charbonnier, Magali Torres, Frederic Gallardo, Charles-Henri Lecellier, Tom Sexton, Simona Saccani, Salvatore Spicuglia

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2023, 51 (10), pp.4845-4866. ⟨10.1093/nar/gkad187⟩

The action of cis-regulatory elements with either activation or repression functions underpins the precise regulation of gene expression during normal development and cell differentiation. Gene activation by the combined activities of promoters and d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f251cd5a4a94c26385ec4ca6a5de3b35
https://cnrs.hal.science/hal-04044391

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Akademický článek

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[Functions of lncRNA in development and diseases]

Autor: Eve-Lyne, Mathieu, Mohamed, Belhocine, Lan T M, Dao, Denis, Puthier, Salvatore, Spicuglia

Publikováno v: Medecine sciences : M/S. 30(8-9)

The transcription of essentially the entire eukaryotic genome generates a myriad of non-coding RNA species that show complex overlapping patterns of expression and regulation. In the last decade, several large scale genomic analyses have shed light o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e61a1547fadee9c0d97aba75a0f5832f
https://pubmed.ncbi.nlm.nih.gov/25174757

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