Zobrazeno 1 - 10
of 3 381
pro vyhledávání: '"Lan K"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Signal processing by intracellular kinases controls near all biological processes but how signal pathway functions evolve with changed cellular context is poorly understood. Functional specificity of c-Jun N-terminal Kinases (JNK) are partly
Externí odkaz:
https://doaj.org/article/287d2d47a12146408d77c44dc16e7549
Autor:
Hon Yan Kelvin Yip, Sung-Young Shin, Annabel Chee, Ching-Seng Ang, Fernando J. Rossello, Lee Hwa Wong, Lan K. Nguyen, Antonella Papa
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-21 (2024)
Abstract Utility of PI3Kα inhibitors like BYL719 is limited by the acquisition of genetic and non-genetic mechanisms of resistance which cause disease recurrence. Several combination therapies based on PI3K inhibition have been proposed, but a way t
Externí odkaz:
https://doaj.org/article/aa1b44a3480a4139b466b6fbd7dfcf75
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 16, Pp 1041-1053 (2023)
Yuanfeng Zhang,1,* Yang Chen,2,* Zhiming Chen,3 Xinye Zhou,4 Shaochuan Chen,1 Kaijian Lan,1 Zhiping Wang,5 Yonghai Zhang1 1Department of Urology, Shantou Central Hospital, Shantou, People’s Republic of China; 2Department of Nursing, Bishan
Externí odkaz:
https://doaj.org/article/ada522a0e02141a9ab3ac6a648971eec
Autor:
Anh T. Nguyen, Zachary Amigo, Kathleen McDuffie, Victoria C. MacQueen, Lane D. Bell, Lan K. Truong, Gloria Batchi, Sara M. McMillin
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 7, Iss 2, Pp n/a-n/a (2024)
ABSTRACT Background Sodium glucose‐linked transporter 2 (SGLT2) inhibitors promote glucose, and therefore calorie, excretion in the urine. Patients taking SGLT2 inhibitors typically experience mild weight loss, but the amount of weight loss falls s
Externí odkaz:
https://doaj.org/article/ccb11baa871045f0b709f966c9954579
Autor:
Milad Ghomlaghi, Mandy Theocharous, Nhan Hoang, Sung-Young Shin, Alex von Kriegsheim, Eric O’ Neill, Tao Zhang, Lan K. Nguyen
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109031- (2024)
Summary: The transcriptional co-activator YAP forms complexes with distinct transcription factors, controlling cell fate decisions, such as proliferation and apoptosis. However, the mechanisms underlying its context-dependent function are poorly defi
Externí odkaz:
https://doaj.org/article/ac43d1e023b14adeb764bd7c42e1ff0f
Autor:
John F. Cooper, Shadia R. Habbal, Benjamin Boe, Vassilis Angelopoulos, David G. Sibeck, Nikolaos Paschalidis, Edward C. Sittler, Lan K. Jian, Rosemary M. Killen
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 10 (2023)
In the present decade and beyond, now 51 years after the last Apollo landing, the NASA Artemis human exploration program will offer abundant opportunities for heliophysics investigations from, by, and of the Moon from the vantage points of the lunar
Externí odkaz:
https://doaj.org/article/605c9020a1ea48f7a5618280a36c8bbb
Autor:
Sanchita Pal, Luiz F. G. dos Santos, Andreas J. Weiss, Thomas Narock, Ayris Narock, Teresa Nieves-Chinchilla, Lan K. Jian, Simon W. Good
Publikováno v:
The Astrophysical Journal, Vol 972, Iss 1, p 94 (2024)
Detecting large-scale flux ropes (FRs) embedded in interplanetary coronal mass ejections (ICMEs) and assessing their geoeffectiveness are essential, since they can drive severe space weather. At 1 au, these FRs have an average duration of 1 day. Thei
Externí odkaz:
https://doaj.org/article/4fb04f8a352f48ac8808704592125612
Autor:
Tarik Mohammad Salman, Teresa Nieves-Chinchilla, Lan K. Jian, Noé Lugaz, Fernando Carcaboso, Emma E. Davies, Yaireska M. Collado-Vega
Publikováno v:
The Astrophysical Journal, Vol 966, Iss 1, p 118 (2024)
We present a statistical investigation of the radial evolution of 28 interplanetary coronal mass ejections (ICMEs), measured in situ by the Parker Solar Probe spacecraft from 2018 October to 2022 August. First, by analyzing the radial distribution of
Externí odkaz:
https://doaj.org/article/17e086afd9a34a8e9d4b4819033c0be5
Autor:
Jia Huang, J. C. Kasper, Davin E. Larson, Michael D. McManus, P. Whittlesey, Roberto Livi, Ali Rahmati, Orlando Romeo, K. G. Klein, Weijie Sun, Bart van der Holst, Zhenguang Huang, Lan K. Jian, Adam Szabo, J. L. Verniero, C. H. K. Chen, B. Lavraud, Mingzhe Liu, Samuel T. Badman, Tatiana Niembro, Kristoff Paulson, M. Stevens, A. W. Case, Marc Pulupa, Stuart D. Bale, J. S. Halekas
Publikováno v:
The Astrophysical Journal Supplement Series, Vol 271, Iss 2, p 66 (2024)
Externí odkaz:
https://doaj.org/article/8995e94648014064a97c5badb79c61d9
Autor:
Elizabeth A. Jensen, Nat Gopalswamy, Lynn B. Wilson, Lan K. Jian, Shing F. Fung, Teresa Nieves-Chinchilla, Marta Shelton, Lihua Li, Manohar Deshpande, Lloyd Purves, Joseph Lazio, Ward B. Manchester, Brian E. Wood, Jason E. Kooi, David B. Wexler, Stuart Bale, Alexei Pevtsov, Bernard V. Jackson, Megan N. Kenny
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 10 (2023)
There continue to be open questions regarding the solar wind and coronal mass ejections (CMEs). For example: how do magnetic fields within CMEs and corotating/stream interaction regions (CIRs/SIRs) evolve in the inner heliosphere? What is the radiall
Externí odkaz:
https://doaj.org/article/3f143b2b35364dbba9f23cc3df356581