A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity.

Autor: Colon-Moran W; Division of Cellular and Gene Therapies, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Baer A; Division of Cellular and Gene Therapies, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Lamture G; Division of Cellular and Gene Therapies, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA.; Adicet Bio, Inc., Menlo Park, CA, USA., Stapleton JT; Research Service, Iowa City Veterans Affairs Medical Center, Iowa City, IA, USA.; Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, IA, USA., Fischer JW; Division of Cellular and Gene Therapies, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA.; AstraZeneca, Gaithersburg, MD, USA., Bhattarai N; Division of Cellular and Gene Therapies, Office of Tissues and Advanced Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA. nirjal.bhattarai@fda.hhs.gov.

Publikováno v: Gene therapy [Gene Ther] 2022 Nov; Vol. 29 (10-11), pp. 616-623. Date of Electronic Publication: 2021 Nov 11.

Synthesis of Tetrahydrocarbazole-Tethered Triazoles as Compounds Targeting Telomerase in Human Breast Cancer Cells.

Autor: Uppar, Pradeep M.¹ (AUTHOR) pradeepmu5@gmail.com, Ravish, Akshay¹ (AUTHOR) akshayrv533@gmail.com, Xi, Zhang² (AUTHOR) zhangxi@szbl.ac.cn, Kumar Harish, Keshav³ (AUTHOR) keshavkumar@physics.uni-mysore.ac.in, Kumar, Arun M.¹ (AUTHOR) arunmysore3@gmail.com, Poonacha, Lisha K.⁴ (AUTHOR) lishakuppanda@gmail.com, Swaroop, Toreshettahally R.¹ (AUTHOR) swarooptr@gmail.com, Somu, Chaithanya⁵ (AUTHOR) chaithanyas268@gmail.com, Gaonkar, Santosh L.⁶ (AUTHOR) sl.gaonkar@manipal.edu, Madegowda, Mahendra³ (AUTHOR) mahendra@physics.uni-mysore.ac.in, Lobie, Peter E.^2,7,8 (AUTHOR) pelobie@sz.tsinghua.edu.cn, Pandey, Vijay^7,8 (AUTHOR) vijay.pandey@sz.tsinghua.edu.cn, Basappa, Basappa¹ (AUTHOR) vijay.pandey@sz.tsinghua.edu.cn

Publikováno v: Catalysts (2073-4344). Oct2024, Vol. 14 Issue 10, p726. 17p.

Actinomycin-D and dimethylamino-parthenolide synergism in treating human pancreatic cancer cells.

Autor: Lamture G; University of Arkansas for Medical Sciences, Little Rock, Arkansas., Crooks PA; University of Arkansas for Medical Sciences, Little Rock, Arkansas., Borrelli MJ; University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Publikováno v: Drug development research [Drug Dev Res] 2018 Sep; Vol. 79 (6), pp. 287-294. Date of Electronic Publication: 2018 Sep 17.

Synthesis and anti-cancer screening of novel heterocyclic-(2 H )-1,2,3-triazoles as potential anti-cancer agents.

Autor: Penthala NR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Madhukuri L; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205-7199, U.S.A., Thakkar S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Madadi NR; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Lamture G; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Eoff RL; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205-7199, U.S.A., Crooks PA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

Publikováno v: MedChemComm [Medchemcomm] 2015 Aug 01; Vol. 6 (8), pp. 1535-1543. Date of Electronic Publication: 2015 Jun 30.

Recent Advances of Tubulin Inhibitors Targeting the Colchicine Binding Site for Cancer Therapy.

Autor: Hawash, Mohammed¹ (AUTHOR) mohawash@najah.edu

Publikováno v: Biomolecules (2218-273X). Dec2022, Vol. 12 Issue 12, p1843. 22p.