Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Lampson GP"'
Publikováno v:
The Journal of General Physiology
A discussion of factors considered influential in making a polynucleotide an efficient inducer of interferon was presented. These factors were double-strandedness of the polynucleotides, the sugar moiety of the polynucleotides, thermal stability, res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93535de1d5811aa8e21697e4e267c722
https://pubmed.ncbi.nlm.nih.gov/19873677
https://pubmed.ncbi.nlm.nih.gov/19873677
Publikováno v:
JAMA: The Journal of the American Medical Association. 276:1793
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d60a50904f274635e4910ddd9d23b2e
https://doi.org/10.1001/jama.1996.03540220017010
https://doi.org/10.1001/jama.1996.03540220017010
Autor:
Robert R. Roehm, Alexander U. Bertland, Maurice R. Hilleman, Lampson Gp, Eugene B. Buynak, Alfred A. Tytell
Publikováno v:
Experimental Biology and Medicine. 151:694-700
Highly purified hepatitis B virus surface antigen (Australia antigen) purified by physical and chemical procedures from infected human plasma was used to prepare hepatitis B vaccine. The purified antigen was treated with formalin and the vaccine was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a8e3da33856170a8adde5447bc475d
https://doi.org/10.3181/00379727-151-39288
https://doi.org/10.3181/00379727-151-39288
Publikováno v:
Journal of Interferon Research. 1:539-549
A soluble complex of poly I:C and poly-L-lysine (poly I:C/poly-L-lysine) has been prepared that induces high titers of circulating interferon in monkeys. By limiting the molar ratio of lysine to nucleotide to 0.5, a complex was formed that was solubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd957c0412993910ac0e43d77be2fd3f
https://doi.org/10.1089/jir.1981.1.539
https://doi.org/10.1089/jir.1981.1.539
Publikováno v:
Experimental Biology and Medicine. 135:911-916
SummaryPreparations of high molecular weight rIn:rCn were exposed to sonic radiation. A decrease in the average molecular weight of the polynucleotide complexes after treatment was accompanied by an exponential decrease in viscosity of the preparatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad6650187ff4098aeba6a995d746b25
https://doi.org/10.3181/00379727-135-35169
https://doi.org/10.3181/00379727-135-35169
Publikováno v:
Experimental Biology and Medicine. 132:776-783
SummaryStudies were conducted in mice and chicks to measure the prophylactic and therapeutic efficacy of poly I:C in a variety of infections by both DNA and RNA viruses. Drug and virus were given by a variety of routes in a number of different regime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc5522a90243e38166f87cc362aaaac
https://doi.org/10.3181/00379727-132-34308
https://doi.org/10.3181/00379727-132-34308
Publikováno v:
Experimental Biology and Medicine. 132:212-218
SummaryCertain basic polyamines, such as neomycin, neamine, kanamycin, streptomycin, and spermine, added to poly I:C increased the Tm. The degree of termal stabilization was influenced by the molecular ratio of polyamine to poly I:C and by the ionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed51df0592ddc85dbe098cefd8532b4d
https://doi.org/10.3181/00379727-132-34182
https://doi.org/10.3181/00379727-132-34182
Publikováno v:
Experimental Biology and Medicine. 141:440-444
SummaryNucleic acid preparations from unpurified concentrates of Newcastle disease virus, Sindbis virus and Semliki Forest virus were found to contain up to 2% double-stranded RNA. Double-stranded RNA was identified by reaction with antisera specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97db9d5449c40ce6a4c493c69555ed3
https://doi.org/10.3181/00379727-141-36793
https://doi.org/10.3181/00379727-141-36793
Comparison of Neutralization and Hemagglutination-Inhibition Techniques for Measuring Mumps Antibody
Autor:
Robert R. Roehm, Maurice R. Hilleman, Lampson Gp, J. E. Whitman, Eugene B. Buynak, David H. Morton
Publikováno v:
Experimental Biology and Medicine. 125:1068-1071
SummaryMumps hemagglutinating antigen treated with Tween 80 and ether showed 2- to 4-fold enhancement of hemagglutinin titer. The hemagglutinating activity of the treated antigen was stable on free...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bc4f339a801afaa4518a6e9d26d3e1
https://doi.org/10.3181/00379727-125-32278
https://doi.org/10.3181/00379727-125-32278
Autor:
D. P. Metzgar, Alfred A. Tytell, A. F. Woodhour, Maurice R. Hilleman, Lampson Gp, R. A. Machlowittz
Publikováno v:
Experimental Biology and Medicine. 123:778-782
SummaryThe development and animal testing of a bivalent influenza virus vaccine in immunologic adjuvant 65 employing a new highly purified viral antigen is described. The enhancement of serologic response to the highly purified viral antigen in adjuv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f4ca1ab7639c011b4acf7d1182d2dd
https://doi.org/10.3181/00379727-123-31601
https://doi.org/10.3181/00379727-123-31601