Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lampouguin Yenkoidiok-Douti"'
Autor:
Lampouguin Yenkoidiok-Douti, Gaspar E. Canepa, Ana Beatriz F. Barletta, Carolina Barillas-Mury
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
An effective vaccine to reduce malaria transmission is central to control and ultimately achieve disease eradication. Recently, we demonstrated that antibodies targeting the Plasmodium falciparum surface protein P47 (Pfs47) reduce parasite transmissi
Externí odkaz:
https://doaj.org/article/55817fd01c9b4ca0a5e781c4c3f5aff4
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Extracellular vesicles (EVs), such as exosomes, have been identified as regulators of vascular remodeling and have promise as therapeutics for vascularization applications. Towards development of EVs as therapeutics, it has been demonstrated
Externí odkaz:
https://doaj.org/article/b0e1adb5d70d429f8324fe85298d360b
Autor:
Eric Calvo, Alvaro Molina-Cruz, John F. Andersen, Carolina Barillas-Mury, Adeline E. Williams, Thiago Luiz Alves e Silva, Lampouguin Yenkoidiok-Douti, Bianca M. Nagata, Gaspar E. Canepa, Martin J. Boulanger, Simardeep Nagyal
Publikováno v:
Proceedings of the National Academy of Sciences. 117:2597-2605
The surface protein Pfs47 allows Plasmodium falciparum parasites to survive and be transmitted by making them "undetectable" to the mosquito immune system. P. falciparum parasites express Pfs47 haplotypes compatible with their sympatric vectors, whil
Autor:
Carolina Barillas-Mury, Fabio M. Gomes, Gaspar E. Canepa, Lampouguin Yenkoidiok-Douti, Alvaro Molina-Cruz, Banhisikha Saha, Miles D W Tyner, Ana Beatriz F. Barletta
Publikováno v:
Proc Natl Acad Sci U S A
Significance A previous Plasmodium infection enhances the mosquito immune response to subsequent infections. Priming is mediated by a hemocyte differentiation factor (HDF) consisting of lipoxin A 4 (LXA 4 ) bound to Evokin, a lipid carrier. Insects p
Autor:
Carolina Barillas-Mury, Lampouguin Yenkoidiok-Douti, Gaspar E. Canepa, Adeline E. Williams, Alvaro Molina-Cruz
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
We recently characterized Pfs47, a protein expressed on the surface of sexual stages and ookinetes of Plasmodium falciparum, as a malaria transmission-blocking vaccine (TBV) target. Mice immunization induced antibodies that conferred strong transmiss
Publikováno v:
ACS Biomater Sci Eng
The development of effective malaria vaccines remains a global health priority. In addition to an effective vaccine, there is urgent demand for effective delivery technologies that can be easily deployed. The need for effective vaccine delivery tools
Publikováno v:
ACS Biomater Sci Eng
Despite the success of vaccines in preventing many infectious diseases, effective vaccines against pathogens with ongoing challenges - such as HIV, malaria, and tuberculosis - remain unavailable. The emergence of new pathogen variants, the continued
Autor:
Gaspar E. Canepa, Ana Beatriz F. Barletta, Carolina Barillas-Mury, Lampouguin Yenkoidiok-Douti
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology
An effective vaccine to reduce malaria transmission is central to control and ultimately achieve disease eradication. Recently, we demonstrated that antibodies targeting the Plasmodium falciparum surface protein P47 (Pfs47) reduce parasite transmissi
Autor:
Carolina Barillas-Mury, Eric Calvo, Fangni Peng, Gaspar E. Canepa, Alvaro Molina-Cruz, David L. Narum, Martin J. Boulanger, Adeline E. Williams, Lampouguin Yenkoidiok-Douti, Martin Burkhardt, Jesus G. Valenzuela
Publikováno v:
npj Vaccines, Vol 3, Iss 1, Pp 1-9 (2018)
Transmission-blocking vaccines are based on eliciting antibody responses in the vertebrate host that disrupt parasite development in the mosquito vector and prevent malaria transmission. The surface protein Pfs47 is present in Plasmodium falciparum g
Autor:
Gaspar E, Canepa, Alvaro, Molina-Cruz, Lampouguin, Yenkoidiok-Douti, Eric, Calvo, Adeline E, Williams, Martin, Burkhardt, Fangni, Peng, David, Narum, Martin J, Boulanger, Jesus G, Valenzuela, Carolina, Barillas-Mury
Publikováno v:
NPJ Vaccines
Transmission-blocking vaccines are based on eliciting antibody responses in the vertebrate host that disrupt parasite development in the mosquito vector and prevent malaria transmission. The surface protein Pfs47 is present in Plasmodium falciparum g