Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows

Autor: Lampignano , R., Neumann, M., Weber, S., Kloten, V., Herdean, A., Voss, T., Groelz, D., Babayan, A., Tibbesma, M., Schlumpberger, M., Chemi, F., Rothwell, D., Wikman, H., Galizzi, J., Bergheim, I., Russnes, H., Mussolin, B., Bonin, S., Voigt, C., Musa, H., Pinzani, P., Lianidou, E., Brady, G., Speicher, M., Pantel, K., Betsou, F., Schuuring, E., Kubista, M., Ammerlaan, W., Sprenger-Haussels, M., Schlange, T., Heitzer, E., Lehrach, H., Yaspo, M.

Publikováno v: Clinical Chemistry : International Journal of Molecular Diagnostics and Laboratory Medicine
Clinical Chemistry
Clinical Chemistry, 66(1), 149-160. AMER ASSOC CLINICAL CHEMISTRY

BACKGROUNDIn cancer patients, circulating cell-free DNA (ccfDNA) can contain tumor-derived DNA (ctDNA), which enables noninvasive diagnosis, real-time monitoring, and treatment susceptibility testing. However, ctDNA fractions are highly variable, whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49907e8af53f9610c711a42c26a883cb
https://hdl.handle.net/10453/145203

Multicenter Evaluation of Circulating Plasma MicroRNA Extraction Technologies for the Development of Clinically Feasible Reverse Transcription Quantitative PCR and Next-Generation Sequencing Analytical Work Flows

Autor: Kloten, V, Neumann, MHD, Di Pasquale, F, Sprenger-Haussels, M, Shaffer, JM, Schlumpberger, M, Herdean, A, Betsou, F, Ammerlaan, W, Af Hällström, T, Serkkola, E, Forsman, T, Lianidou, E, Sjöback, R, Kubista, M, Bender, S, Lampignano, R, Krahn, T, Schlange, T, CANCER-ID consortium

BACKGROUND: In human body fluids, microRNA (miRNA) can be found as circulating cell-free miRNA (cfmiRNA), as well as secreted into extracellular vesicles (EVmiRNA). miRNAs are being intensively evaluated as minimally invasive liquid biopsy biomarkers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::edac7485d9038541f18db95d49f46423
https://hdl.handle.net/10453/160225

Isolation of circulating tumor cells from diagnostic leukapheresis

Autor: Andree, Kiki Carlijn, Mentink-Leusink, Anouk, Scholz, M., Kirchner, R., Neves, R.P., Driemel, C., Lampignano, R., Neubauer, H., Niederacher, D., Fischer, J.C., Stoecklein, N.H., Terstappen, Leonardus Wendelinus Mathias Marie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0b228446d9ca7a6370df5996543f489d
https://research.utwente.nl/en/publications/46982371-df06-4ed5-9a51-7d48a6a99493

597 - Genomic characterization of putative CTCs isolated from CellSearch® discarded fractions by Parsortix system and Cellcelector micromanipulator

Autor: Nini, A., Lampignano, R., Behrens, B., Yang, L., Steinau, L., Fehm, T., Niegisch, G., Lorch, A., Hoffmann, M., Große Siemer, R., Albers, P., Schulz, W., Stoecklein, N., Neubauer, H.

Publikováno v: In European Urology Supplements March 2018 17(2):e859-e859

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