Comparison of the CYP3A Selective Inhibitors CYP3cide, Clobetasol, and Azamulin for Their Potential to Distinguish CYP3A7 Activity in the Presence of CYP3A4/5.

Autor: Work HM; Department of Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado (H.M.W., S.E.K., J.N.L.)., Kandel SE; Department of Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado (H.M.W., S.E.K., J.N.L.)., Lampe JN; Department of Pharmaceutical Sciences, University of Colorado, Anschutz Medical Campus, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado (H.M.W., S.E.K., J.N.L.) jed.lampe@cuanschutz.edu.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 Oct 16; Vol. 52 (11), pp. 1224-1233. Date of Electronic Publication: 2024 Oct 16.

HCV Antiviral Drugs Have the Potential to Adversely Perturb the Fetal-Maternal Communication Axis through Inhibition of CYP3A7 DHEA-S Oxidation.

Autor: Work HM; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, Colorado (H.M.W., J.N.L.); and Biomolecular Sciences Institute & Department of Chemistry & Biochemistry, School of Integrated Science & Humanity, College of Arts, Sciences, & Education, Florida International University, Miami, Florida (J.C.H.)., Hackett JC; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, Colorado (H.M.W., J.N.L.); and Biomolecular Sciences Institute & Department of Chemistry & Biochemistry, School of Integrated Science & Humanity, College of Arts, Sciences, & Education, Florida International University, Miami, Florida (J.C.H.)., Lampe JN; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, Colorado (H.M.W., J.N.L.); and Biomolecular Sciences Institute & Department of Chemistry & Biochemistry, School of Integrated Science & Humanity, College of Arts, Sciences, & Education, Florida International University, Miami, Florida (J.C.H.) jed.lampe@cuanschutz.edu.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 May 16; Vol. 52 (6), pp. 516-525. Date of Electronic Publication: 2024 May 16.

Correction: Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate.

Autor: Liu J, Kandel SE, Lampe JN, Scott EE

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Oct; Vol. 299 (10), pp. 105283. Date of Electronic Publication: 2023 Sep 30.

Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims.

Autor: Malachowska B; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Yang WL; Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Qualman A; Department of Surgery; Division of G.I., Trauma, and Endocrine Surgery, University of Colorado, Aurora, CO, 80045, USA., Muro I; Department of Surgery; Division of G.I., Trauma, and Endocrine Surgery, University of Colorado, Aurora, CO, 80045, USA., Boe DM; Department of Surgery; Division of G.I., Trauma, and Endocrine Surgery, University of Colorado, Aurora, CO, 80045, USA.; Graduate Program in Immunology, University of Colorado, Aurora, CO, 80045, USA., Lampe JN; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado, Aurora, CO, 80045, USA., Kovacs EJ; Department of Surgery; Division of G.I., Trauma, and Endocrine Surgery, University of Colorado, Aurora, CO, 80045, USA.; Graduate Program in Immunology, University of Colorado, Aurora, CO, 80045, USA.; Molecular Biology Program, University of Colorado, Aurora, CO, 80045, USA., Idrovo JP; Department of Surgery; Division of G.I., Trauma, and Endocrine Surgery, University of Colorado, Aurora, CO, 80045, USA. juan.idrovo@cuanschutz.edu.

Publikováno v: Communications biology [Commun Biol] 2023 Jun 02; Vol. 6 (1), pp. 597. Date of Electronic Publication: 2023 Jun 02.

Cefadroxil Comparable to Cephalexin: Minimum Inhibitory Concentrations among Methicillin-Susceptible Staphylococcus aureus Isolates from Pediatric Musculoskeletal Infections.

Autor: Haynes AS; Children's Hospital Colorado, Department of Pediatrics, Section of Pediatric Infectious Diseases, Aurora, Colorado, USA.; University of Colorado Anschutz Medical Campusgrid.430503.1, School of Medicine, Aurora, Colorado, USA., Prinzi A; Children's Hospital Colorado, Department of Pediatrics, Section of Pediatric Infectious Diseases, Aurora, Colorado, USA.; University of Colorado Anschutz Medical Campusgrid.430503.1, Graduate School, Aurora, Colorado, USA., Silveira LJ; University of Colorado Anschutz Medical Campusgrid.430503.1, School of Medicine, Aurora, Colorado, USA., Parker SK; Children's Hospital Colorado, Department of Pediatrics, Section of Pediatric Infectious Diseases, Aurora, Colorado, USA.; University of Colorado Anschutz Medical Campusgrid.430503.1, School of Medicine, Aurora, Colorado, USA., Lampe JN; University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA., Kavanaugh JS; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA., Horswill AR; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.; Department of Veterans Affairs, Eastern Colorado Healthcare System, Aurora, Colorado, USA., Fish D; University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado, USA.

Publikováno v: Microbiology spectrum [Microbiol Spectr] 2022 Aug 31; Vol. 10 (4), pp. e0103922. Date of Electronic Publication: 2022 Jun 22.